Welcome to our dedicated page for NeuroBo Pharmaceuticals news (Ticker: NRBO), a resource for investors and traders seeking the latest updates and insights on NeuroBo Pharmaceuticals stock.
NeuroBo Pharmaceuticals, Inc. (NASDAQ: NRBO) is a clinical-stage biotechnology company dedicated to developing and commercializing transformative therapies for cardiometabolic diseases. Headquartered in Boston, Massachusetts, and established in 2017, NeuroBo is at the forefront of innovative solutions aimed at conditions like obesity, metabolic dysfunction-associated steatohepatitis (MASH), and Type 2 Diabetes Mellitus (T2DM).
The company's robust product pipeline includes two primary programs:
- DA-1241: This novel G-Protein-Coupled Receptor 119 (GPR119) agonist aims to treat MASH and T2DM. In preclinical studies, DA-1241 has shown promising results in reducing hepatic steatosis, inflammation, liver fibrosis, and improving glucose control. The Phase 2a clinical trial is currently evaluating its efficacy and safety, with an expected data readout in the second half of 2024.
- DA-1726: A dual oxyntomodulin (OXM) analog functioning as a glucagon-like peptide-1 receptor (GLP1R) and glucagon receptor (GCGR) agonist, designed to address obesity. Preclinical evidence suggests that DA-1726 offers superior weight loss and a better tolerability profile compared to existing GLP-1 agonists. The Phase 1 clinical trial is underway with an anticipated data readout in the first half of 2025.
In addition to its primary programs, NeuroBo continues to advance its legacy therapeutics, including ANA001 for viral diseases, NB-01 for painful diabetic neuropathy, NB-02 for neurodegenerative diseases, and Gemcabene for dyslipidemia. The company's commitment to leveraging advanced biotechnology aims to meet significant unmet medical needs, providing patients with novel, effective treatments.
Recent achievements include FDA clearance for the IND application of DA-1726 and the initiation of Phase 1 clinical trials. NeuroBo also secured Institutional Review Board (IRB) approval to further expedite their research and development processes.
For more comprehensive information, please visit NeuroBo Pharmaceuticals' official website.
NeuroBo Pharmaceuticals (Nasdaq: NRBO) reported its financial results for the year ended December 31, 2021, revealing a net loss of $15.3 million, improving from $29.7 million in 2020. R&D expenses increased to $6.5 million, primarily due to clinical trial costs for its lead drug candidate, ANA001, targeting moderate to severe COVID-19. General and administrative expenses rose to $8.8 million. The company ended 2021 with $16.4 million in cash, projecting sufficient funds for operations into Q4 2022. Clinical progress on ANA001 is anticipated in the upcoming quarters.
NeuroBo Pharmaceuticals (Nasdaq: NRBO) announced the immediate appointment of Danamarie Belpulsi, M.D., to its Scientific Advisory Board as of March 15, 2022. Dr. Belpulsi brings expertise in infectious diseases, cardiology, and neurology, which is expected to enhance clinical trial strategies and advance the company's programs, particularly ANA-001. Currently serving as Medical Director at ICON plc, her extensive background includes consulting for numerous biotech companies and research roles at Columbia University. This addition is anticipated to strengthen NeuroBo's clinical development initiatives.
On January 28, 2022, NeuroBo Pharmaceuticals (Nasdaq: NRBO) announced the appointment of D. Gordon Strickland to its Board of Directors, effective January 27, 2022. Mr. Strickland, an accomplished executive with over 35 years of leadership experience, will serve as Chair of the Audit Committee. His past roles include Chairman and CEO positions at notable firms, contributing valuable expertise as NeuroBo aims for growth and value creation. The announcement comes amid ongoing efforts to enhance the company's strategic direction and operational effectiveness.
NeuroBo Pharmaceuticals (Nasdaq: NRBO) reported its third quarter financial results for 2021, highlighting a net loss of $3.5 million or $0.16 per share, compared to a loss of $3.1 million or $0.19 per share in the previous year. R&D expenses increased to $1.4 million from $1.3 million, while G&A expenses rose to $2.1 million from $1.8 million. The company successfully raised $14 million through a direct offering, extending its cash runway into Q4 2022. NeuroBo is advancing its Phase 2/3 clinical trial for ANA001, targeting COVID-19.
NeuroBo Pharmaceuticals (Nasdaq: NRBO) announced the appointment of Gil Price, M.D. as President and CEO, replacing Dr. Richard J. Kang, who will remain on the Board. This leadership change aims to advance NeuroBo’s clinical strategy, particularly in its COVID-19 program. Dr. Price, with extensive experience in clinical development, previously served at ProPharma Group and MedImmune. An inducement grant was also approved for Dr. Price, allowing him to purchase 616,666 shares at $2.04 each. This transition is expected to strengthen NeuroBo's position in developing disease-modifying therapies.
NeuroBo Pharmaceuticals (Nasdaq: NRBO) announced a positive recommendation from an independent Data Monitoring Committee (DMC) regarding its Phase 2/3 trial of ANA001, an oral niclosamide formulation for COVID-19 treatment. The DMC reviewed safety data from 36 patients and recommended continuing the trial without modifications. This two-part study aims to assess safety, tolerability, and efficacy in hospitalized patients. The company plans to complete the Phase 2 portion by Q4 2021 and initiate Phase 3 shortly thereafter, aiming to address the ongoing need for effective COVID-19 therapies.
NeuroBo Pharmaceuticals (NASDAQ: NRBO) announced the completion of a registered direct offering, selling 4,307,693 shares at $3.25 each, raising approximately $12.7 million in net proceeds. The offering includes unregistered warrants with an exercise price of $3.75, exercisable in six months for three and a half years. The funds will be used for working capital, capital expenditures, and general corporate purposes. NeuroBo focuses on developing therapies for viral and neurodegenerative diseases, with ongoing clinical trials for its drug candidates.
NeuroBo Pharmaceuticals (NRBO) announced a registered direct offering to sell 4,307,693 shares of common stock at $3.25 per share, aiming to raise approximately $14 million in gross proceeds. Concurrently, the company will issue warrants for the same number of shares at an exercise price of $3.75, exercisable after six months for 3.5 years. The net proceeds will support working capital and general corporate purposes. The offering's closing is expected around October 5, 2021.
NeuroBo Pharmaceuticals (NRBO) reported its Q2 2021 financial results, showing a net loss of $3.9 million, or $0.18 per share, widening from a $2.4 million loss in Q2 2020. R&D expenses rose to $2.0 million, reflecting increased clinical activity. Despite cash reserves decreasing to $9.5 million as of June 30, 2021, NeuroBo expects sufficient liquidity to support operations into Q1 2022. Enrollment in the Phase 2/3 trial for its COVID-19 treatment, ANA001, is expected to conclude by Q4 2021, aided by the Delta variant's impact on hospitalization rates.
On July 9, 2021, NeuroBo Pharmaceuticals (Nasdaq: NRBO) held its Annual Meeting of Shareholders, where Hyung Heon Kim and Andrew I. Koven were elected to its Board of Directors. This Board now consists of seven directors, with six independent members. CEO Richard J. Kang expressed optimism about the new members' industry expertise aiding the advancement of NeuroBo's pipeline, including their lead asset, ANA001, for COVID-19. The company is progressing with various drug candidates targeting viral and neurodegenerative diseases, including a promising Phase 2/3 trial for ANA001.
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