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Novo Nordisk reports adjusted operating profit of DKK 33,389 million for Q2 2026 and raises full-year outlook

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Novo Nordisk (NYSE:NVO) reported Q2 2026 net sales of DKK 78,488 million, up 3% at constant exchange rates (CER), while reported operating profit fell 16% at CER to DKK 27,061 million, impacted by prior-year US 340B rebate provision reversals and DKK 6.3 billion non-cash impairments to intangible pipeline assets, including DKK 4.0 billion for monlunabant.

Q2 2026 adjusted sales rose 7% at CER and adjusted operating profit increased 11% at CER to DKK 33,389 million, driven by GLP-1 volume growth and favourable US rebate adjustments. Wegovy pill has surpassed 5 million prescriptions in the US, with weekly prescriptions above 265,000, and has launched in the UAE and UK. EMA approved Wegovy 7.2 mg pen and Wegovy pill based on data showing up to 20.7% and 16.6% mean weight loss, respectively. The ZEUS phase 3 trial with ziltivekimab did not meet its primary endpoint. Full-year 2026 adjusted sales and adjusted operating profit growth are now guided to 0% to -6% at CER.

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Positive

  • Q2 2026 adjusted sales DKK 78,488 million, +7% at CER
  • Q2 2026 adjusted operating profit DKK 33,389 million, +11% at CER
  • H1 2026 reported operating profit DKK 86,679 million, +27% at CER
  • Wegovy pill US uptake over 5 million prescriptions and 265,000 weekly scripts
  • EMA approvals for Wegovy 7.2 mg pen and Wegovy pill with up to 20.7% and 16.6% mean weight loss
  • 2026 guidance raised for adjusted sales and adjusted operating profit to growth of 0% to -6% at CER

Negative

  • Q2 2026 reported operating profit down 16% at CER to DKK 27,061 million
  • Non-cash impairments DKK 6.3 billion on intangible pipeline assets, including DKK 4.0 billion for monlunabant
  • H1 2026 adjusted operating profit DKK 66,247 million, down 5% in DKK and up only 2% at CER
  • ZEUS phase 3 trial with ziltivekimab did not meet the primary endpoint
  • 2026 adjusted sales and operating profit outlook implies between flat and 6% decline at CER

News Market Reaction – NVO

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-5.97% Session close to close
-10.9% Trough in 50 min
$216.89B Market Cap
4.3x Rel. Volume

In the Aug 4 session, NVO declined 5.97%, reflecting a notable negative market reaction. Argus tracked a trough of -10.9% from its starting point during tracking. Our momentum scanner triggered 30 alerts that day, indicating elevated trading interest and price volatility. Trading volume was very high at 4.3x the daily average, suggesting heavy selling pressure.

Data tracked by StockTitan Argus on the day of publication.

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Bagsværd, 4 August 2026 - Financial report for the period 1 January 2026 to 30 June 2026                                                                                                                                            

Financial performance

  • Q2 2026 reported sales increased by 3% at CER, with growth negatively impacted by a DKK 2.6 billion rebate provision reversal related to the 340B Drug Pricing Program in the US in Q2 2025.
  • Q2 2026 adjusted sales increased by 7% at CER, driven by GLP-1 volume growth across geographies and favourable US rebate adjustments in the quarter.
  • Q2 2026 reported operating profit decreased by 16% at CER, with growth negatively impacted by the US 340B rebate provision reversal in Q2 2025 as well as non-cash impairment charges of DKK 6.3 billion in Q2 2026 related to intangible pipeline assets, including monlunabant (DKK 4.0 billion).
  • Q2 2026 adjusted operating profit increased by 11% at CER.

Commercial highlights

  • Wegovy® pill continues its uptake in the US, and for the week ending 17 July, total weekly prescriptions exceeded 265,000. Measured by new patient starts, the Wegovy® franchise remains the market leader among branded obesity medications in the US.
  • Wegovy® pill was launched in the UAE in June and in the UK in July, with encouraging early uptake observed. In the coming quarters, additional Wegovy® pill launches in other select markets are planned.
  • Wegovy® HD was launched in the US in April, and Wegovy® 7.2 mg single-dose pen in the UK in June. The roll-out of Wegovy® 7.2 mg single-dose pen across the EU is planned in the second half of 2026.

Pipeline progress

  • Within obesity, Wegovy® 7.2 mg single-dose pen received EMA approval in July based on the STEP UP data providing up to 20.7% mean weight loss.
  • Also within obesity, Wegovy® pill received EMA approval in July based on the OASIS 4 data providing up to 16.6% mean weight loss.
  • In cardiovascular disease, the ZEUS phase 3 trial with ziltivekimab did not meet the primary endpoint.

Outlook 

  • Adjusted sales growth for 2026 is now expected to be 0% to -6% at CER and adjusted operating profit growth is now expected to be 0% to -6% at CER. The improved outlook is driven by increased expectations for GLP-1 product sales.

PROFIT AND LOSS
DKK million

Q2 2026Growth
in DKK
Growth
at CER
H1 2026Growth
in DKK
Growth
at CER
       
Net sales        78,488                2%                3%                175,311                13%                18%        
Operating profit        27,061                (19%)        (16%)        86,679                20%                27%        
Adjusted net sales1        78,488                6%                7%                148,551                (2%)        2%        
Adjusted operating profit1,2        33,389                8%                11%                66,247                (5%)        2%        
CER: Constant exchange rates; 1Adjusted sales and adjusted operating profit growth rates exclude the non-recurring impact from the provision reversals related to the 340B Drug Pricing Program in the US. 2Excl. DKK 6.3 billion non-recurring, non-cash impairment charges in Q2 2026 related to intangible pipeline assets, including monlunabant (DKK 4.0 billion).. Further details provided in Appendix 7

“The Wegovy® product portfolio remains a key growth driver for Novo Nordisk in 2026, led by the continued rapid adoption of Wegovy® pill in the US, which has reached more than 5 million prescriptions since its launch, alongside encouraging early uptake in markets outside the US and the rollout of Wegovy® HD (7.2 mg). The increased US GLP-1 momentum, combined with continued growth and new launches in International Operations, has led us to further raise our 2026 guidance for both adjusted sales and adjusted operating profit,” said Mike Doustdar, president and CEO of Novo Nordisk.

On 5 August 2026 at 13.00 CEST, corresponding to 07.00 am EDT, an earnings call will be held. Investors will be able to listen in via a link on novonordisk.com, which can be found under 'Investors' (the contents of the company's website do not form a part of this Form 6-K)


A
bout Novo Nordisk

Novo Nordisk is a leading global healthcare company founded in 1923 and headquartered in Denmark. Our purpose is to drive change to defeat serious chronic diseases built upon our heritage in diabetes. We do so by pioneering scientific breakthroughs, expanding access to our medicines and working to prevent and ultimately cure disease. Novo Nordisk employs about 66,700 people in 80 countries and markets its products in around 170 countries. Novo Nordisk's B shares are listed on Nasdaq Copenhagen (Novo-B). Its ADRs are listed on the New York Stock Exchange (NVO). For more information, visit novonordisk.com, Facebook, X, LinkedIn and YouTube.

Contacts for further information 
Media: 
Ambre James-Brown

+45 3079 9289
globalmedia@novonordisk.com
Liz Skrbkova (US)

+1 609 917 0632
usmediarelations@novonordisk.com

   
Investors: 
Michael Novod
+45 3075 6050
nvno@novonordisk.com
Sina Meyer
+45 3079 6656
azey@novonordisk.com
Alex Bruce
+45 3444 2613
axeu@novonordisk.com
Ida Schaap Melvold
+45 3077 5649
idmg@novonordisk.com
Christoffer Togo Solgaard-Tullin
+45 3079 1471
cftu@novonordisk.com
Mads Berner Bruun
+45 3075 2936
mbbz@novonordisk.com
Frederik Taylor Pitter (US)
+1 609 613 0568
fptr@novonordisk.com
 


About Novo Nordisk

Novo Nordisk is a leading global healthcare company founded in 1923 and headquartered in Denmark. Our purpose is to drive change to defeat serious chronic diseases built upon our heritage in diabetes. We do so by pioneering scientific breakthroughs, expanding access to our medicines and working to prevent and ultimately cure disease. Novo Nordisk employs about 66,700 people in 80 countries and markets its products in around 170 countries. Novo Nordisk's B shares are listed on Nasdaq Copenhagen (Novo-B). Its ADRs are listed on the New York Stock Exchange (NVO). For more information, visit novonordisk.com, Facebook, X, LinkedIn and YouTube.

Contacts for further information 
Media: 
Ambre James-Brown

+45 3079 9289
globalmedia@novonordisk.com
Liz Skrbkova (US)

+1 609 917 0632
usmediarelations@novonordisk.com
   
Investors: 
Michael Novod

+45 3075 6050
nvno@novonordisk.com
Sina Meyer

+45 3079 6656
azey@novonordisk.com
Alex Bruce
+45 3444 2613
axeu@novonordisk.com
Ida Schaap Melvold

+45 3077 5649
idmg@novonordisk.com
Christoffer Togo Solgaard-Tullin

+45 3079 1471
cftu@novonordisk.com
Mads Berner Bruun
+45 3075 2936
mbbz@novonordisk.com
Frederik Taylor Pitter (US)
+1 609 613 0568
fptr@novonordisk.com
 

Company announcement No 48 / 2026

Attachment


FAQ

How did Novo Nordisk (NVO) perform financially in Q2 2026?

Novo Nordisk reported Q2 2026 net sales of DKK 78,488 million, up 3% at CER, and reported operating profit of DKK 27,061 million, down 16% at CER. According to Novo Nordisk, adjusted operating profit rose 11% at CER to DKK 33,389 million.

What is Novo Nordisk’s 2026 guidance for adjusted sales and operating profit?

Novo Nordisk now expects 2026 adjusted sales growth of 0% to -6% at CER and adjusted operating profit growth of 0% to -6% at CER. According to Novo Nordisk, this raised outlook is driven by increased expectations for GLP-1 product sales.

How is Wegovy pill contributing to Novo Nordisk (NVO) growth in 2026?

Wegovy pill is a key growth driver, with more than 5 million US prescriptions and weekly prescriptions above 265,000. According to Novo Nordisk, GLP-1 momentum and early uptake in the UAE and UK support higher adjusted sales and profit guidance.

What clinical trial results did Novo Nordisk report for Q2 2026?

Novo Nordisk reported the ZEUS phase 3 trial with ziltivekimab did not meet its primary endpoint. According to Novo Nordisk, Wegovy 7.2 mg pen and Wegovy pill received EMA approval based on data showing up to 20.7% and 16.6% mean weight loss.

How did impairments affect Novo Nordisk’s Q2 2026 operating profit?

Q2 2026 reported operating profit fell partly due to DKK 6.3 billion non-cash impairments on intangible pipeline assets. According to Novo Nordisk, this included a DKK 4.0 billion impairment related to monlunabant, which weighed on reported profit growth.

What were Novo Nordisk’s H1 2026 sales and operating profit figures?

For H1 2026, Novo Nordisk reported net sales of DKK 175,311 million, up 18% at CER, and operating profit of DKK 86,679 million, up 27% at CER. According to Novo Nordisk, adjusted operating profit was DKK 66,247 million, up 2% at CER.

What were the key regulatory milestones for Wegovy in mid-2026?

In July 2026, the EMA approved Wegovy 7.2 mg single-dose pen and Wegovy pill for obesity. According to Novo Nordisk, STEP UP and OASIS 4 data showed up to 20.7% and 16.6% mean weight loss, supporting these approvals and future EU rollout.