Olema Pharmaceuticals, Inc. Stock Price, News & Analysis

Olema Pharmaceuticals, Inc. (Nasdaq: OLMA) announced the grant of stock options to a new employee for 70,000 shares, effective August 1, 2022. This award, approved by the Compensation Committee, is part of the 2022 Inducement Plan. The options vest over four years, starting with 25% on the first anniversary and the rest in monthly installments. The exercise price is $4.95 per share, matching the stock's last reported sale price. Olema focuses on targeted therapies for women’s cancers, with its lead product, OP-1250, currently in clinical trials for ER-positive breast cancer.

Olema Pharmaceuticals, Inc. (Nasdaq: OLMA) announced that the FDA granted Fast Track designation to its drug OP-1250, a novel oral complete estrogen receptor antagonist and selective ER degrader, for treating ER-positive, HER2-negative metastatic breast cancer. This designation aims to expedite development and review processes, allowing for closer communication with the FDA. OP-1250 is currently in a Phase 1/2 clinical trial and being evaluated in combination with palbociclib. Fast Track designation represents a significant milestone for Olema in addressing unmet medical needs in women's cancer treatments.

Olema Pharmaceuticals, Inc. (Nasdaq: OLMA) announced the grant of stock options to three new employees for a total of 32,000 shares, effective July 1, 2022. Approved by the Compensation Committee, the stock options are part of the 2022 Inducement Plan, vesting over four years with a 10-year term and an exercise price of $4.18 per share. The company aims to attract talent critical for its focus on developing targeted therapies for women's cancers, including its lead candidate, OP-1250, currently in clinical trials for treating ER-positive breast cancer.

Olema Pharmaceuticals reported promising clinical advancements for OP-1250, its compound targeting ER+ / HER2- breast cancer. The Phase 1b study demonstrated favorable tolerability with no grade 3/4 neutropenia and early anti-tumor activity. OP-1250's combinability with palbociclib was confirmed, showing no dose limiting toxicities. Olema plans a pivotal study for OP-1250 in 2023, aiming for continued enrollment in clinical trials through 2024. High enthusiasm from investigators contributed to rapid patient recruitment, reflecting confidence in the candidate's potential.

On June 9, 2022, Olema Pharmaceuticals (Nasdaq: OLMA) announced an exclusive global license agreement with Aurigene Discovery Technologies to develop small molecule inhibitors targeting an undisclosed oncology target. Olema will pay an upfront fee of $8 million, with Aurigene eligible for up to $60 million in clinical milestones and $370 million in commercial milestones. Olema aims to enhance its drug discovery portfolio while maintaining adequate funding for research and development through 2024. This collaboration underscores Olema's focus on cancer treatments for women, particularly with its lead candidate, OP-1250.

On June 2, 2022, Olema Pharmaceuticals granted stock options for 25,400 shares to two new employees under its 2022 Inducement Plan. The options have a grant date of June 1, 2022, with a $2.80 exercise price, matching the last reported sale price. Vested over four years, 25% will vest on the first anniversary, followed by monthly installments. This decision complies with Nasdaq Listing Rule 5635(c)(4). Olema, focused on innovative cancer therapies, is currently evaluating OP-1250 in clinical trials for ER+ breast cancer.

Olema Pharmaceuticals, a clinical-stage biopharmaceutical company focused on women’s cancers, announced that CEO Sean P. Bohen will participate in a fireside chat at the Jefferies Healthcare Conference on June 9, 2022, at 8:30 a.m. ET. The event will be accessible through a live webcast on Olema’s website, which will remain available for 14 days post-event.

Olema’s lead candidate, OP-1250, is undergoing clinical trials for treating ER-positive, HER2-negative breast cancer.

Olema Pharmaceuticals (Nasdaq: OLMA) announced its Q1 2022 results, highlighting strong progress in clinical trials for its lead candidate, OP-1250. The Phase 1/2 trial continues to enroll patients, with the recommended Phase 2 dose expected by Q2 2022. The company has $267.9 million in cash, sufficient to fund operations into 2024. Despite a net loss of $23 million for the quarter—up from $15.3 million year-over-year—investments in OP-1250 are pivotal for growth. Olema plans to present updated clinical data later this year.

Olema Pharmaceuticals, Inc. (Nasdaq: OLMA) announced the granting of stock options for 68,700 shares to three new employees, effective May 2, 2022. The options were approved by the Compensation Committee and are part of the Company's 2022 Inducement Plan. They vest over four years, with an exercise price set at $2.68 per share, equal to the stock's last reported sale price. Olema focuses on targeted therapies for women’s cancers, with its lead candidate, OP-1250, currently in clinical trials for treating ER-positive breast cancer.