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OneMedNet and Navidence Announce Strategic Collaboration: Empowering Pharma with Precision Real-World Data Insights

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OneMedNet (Nasdaq: ONMD) announced a strategic collaboration with Navidence on March 18, 2026 to integrate Navidence Computable Operational Definitions (CODefs) into the OneMedNet iRWD™ platform.

This integration aims to accelerate cohort discovery, improve dataset fitness, and support regulatory‑grade real‑world evidence for pharma and CRO customers.

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News Market Reaction – ONMD

+7.52%
6 alerts
+7.52% News Effect
+7.4% Peak Tracked
-6.2% Trough Tracked
+$3M Valuation Impact
$42M Market Cap
0.0x Rel. Volume

On the day this news was published, ONMD gained 7.52%, reflecting a notable positive market reaction. Argus tracked a peak move of +7.4% during that session. Argus tracked a trough of -6.2% from its starting point during tracking. Our momentum scanner triggered 6 alerts that day, indicating moderate trading interest and price volatility. This price movement added approximately $3M to the company's valuation, bringing the market cap to $42M at that time.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

RWD market size 2025: $1.88 billion RWD market 2034: $6.37 billion RWD market CAGR: 14.54% CAGR
3 metrics
RWD market size 2025 $1.88 billion Global real-world data (RWD) market value in 2025
RWD market 2034 $6.37 billion Projected global RWD market value by 2034
RWD market CAGR 14.54% CAGR Projected 2025–2034 growth rate for RWD market

Market Reality Check

Price: $0.7953 Vol: Volume 423,710 is only 0....
low vol
$0.7953 Last Close
Volume Volume 423,710 is only 0.04x the 20-day average 11,753,613, indicating limited participation. low
Technical Shares at $0.7617 are trading below the 200-day MA of $1.05 and 81.95% under the 52-week high.

Peers on Argus

ONMD fell 5.2% while momentum peers were mixed: two up (e.g., ZCMD +4.89%) and t...
2 Up 2 Down

ONMD fell 5.2% while momentum peers were mixed: two up (e.g., ZCMD +4.89%) and two down (e.g., HCTI -3.36%), suggesting a stock-specific reaction rather than a unified sector move.

Previous Partnership Reports

2 past events · Latest: Feb 24 (Positive)
Same Type Pattern 2 events
Date Event Sentiment Move Catalyst
Feb 24 Strategic partnership Positive +2.4% Neuro data partnership adding EEG/PSG data under multi-year subscription model.
Aug 18 Data partnership Positive +23.7% Circle CVI deal using iRWD™ data under new subscription revenue model.
Pattern Detected

Partnership and collaboration announcements have historically coincided with positive next-day moves for ONMD.

Recent Company History

Over the last year, ONMD has used partnerships to expand its iRWD™ platform and subscription model. Prior deals with Risorius and Circle CVI supported multi‑year subscriptions and access to large imaging datasets from 1,750+ sites and 131 million exams. These partnership headlines saw next‑day gains of 2.42% and 23.68%. Today’s Navidence collaboration continues that strategy, targeting more precise, computable cohort definitions for life‑sciences customers.

Historical Comparison

+13.1% avg move · In the past, ONMD partnership headlines averaged a 13.05% next-day gain. Today’s -5.2% move contrast...
partnership
+13.1%
Average Historical Move partnership

In the past, ONMD partnership headlines averaged a 13.05% next-day gain. Today’s -5.2% move contrasts with that pattern, marking an atypically negative reaction for similar news.

Partnerships have progressively broadened ONMD’s iRWD™ use cases, from cardiovascular and neuro imaging subscriptions to EEG-based biomarkers and now computable cohort definitions with Navidence.

Market Pulse Summary

The stock moved +7.5% in the session following this news. A strong positive reaction aligns with how...
Analysis

The stock moved +7.5% in the session following this news. A strong positive reaction aligns with how ONMD shares historically responded to partnership news, where similar deals around imaging and data subscriptions produced gains averaging 13.05%. Investors have previously rewarded announcements that expand the iRWD™ platform’s scope and recurring revenue potential. However, sustainability would depend on execution, given small-cap fundamentals, past equity offerings, and low typical trading liquidity that can accentuate both upside and subsequent pullbacks.

Key Terms

real-world data (rwd), computable operational definitions (codefs), multimodal datasets, health economics and outcomes research (heor), +1 more
5 terms
real-world data (rwd) technical
"a leading provider of regulatory decision-grade, AI-ready Real-World Data (RWD)"
Real-world data are health and clinical information collected outside controlled clinical trials — from sources such as electronic health records, insurance claims, patient registries, wearable devices and pharmacy records. Investors care because this evidence shows how treatments or medical products actually perform in everyday use, informing market demand, regulatory decisions, reimbursement and commercial forecasts; think of it as street-level traffic data that complements lab tests and reduces uncertainty about real-market performance.
computable operational definitions (codefs) technical
"Navidence’s platform enables precise definition of health data needs via Computable Operational Definitions (CODefs)"
Computable operational definitions (codefs) are precise, machine-readable rules that tell software exactly how to identify and measure clinical events, outcomes, or data elements in electronic records. Like a recipe or a checklist for a computer, they ensure different teams and systems count the same thing the same way, improving consistency, comparability and speed of analysis—factors that affect the reliability of trial results, regulatory review and the valuation of health-data and biotech investments.
multimodal datasets technical
"rapid discovery of fit-for-purpose multimodal datasets, streamlining study design"
Multimodal datasets are collections of information that combine different types of data — such as text, images, audio, and sensor readings — about the same subjects or events, like a photo with a caption and accompanying sound. Think of it as a mixed-media scrapbook that lets algorithms see more of the whole picture. Investors care because these richer datasets can enable more accurate AI-driven products, better customer insights and faster decision-making, which may translate into competitive advantages, higher growth potential and different risk profiles for companies.
health economics and outcomes research (heor) medical
"Health economics and outcomes research (HEOR)Regulatory-grade evidence generation"
Health economics and outcomes research (HEOR) studies how well medical treatments work in the real world and what they cost, combining clinical results, patient experiences, and economic analysis to judge value. For investors, HEOR is like a product report card and price guide: it helps predict whether insurers, hospitals and doctors will adopt and pay for a therapy, influencing sales, pricing power and long-term revenue potential.
real-world evidence technical
"pressure to integrate high-quality RWD for regulatory submissions, post-market surveillance, and AI model training ... actionable real-world evidence"
Real-world evidence is information gathered from everyday sources like patient records, insurance claims, or everyday experiences, rather than controlled experiments or clinical trials. It helps investors understand how products or policies perform in real life, providing a more complete picture of their effectiveness and value beyond official tests. This type of evidence can influence decision-making by offering insights based on actual, everyday outcomes.

AI-generated analysis. Not financial advice.

MINNEAPOLIS, March 18, 2026 (GLOBE NEWSWIRE) -- OneMedNet Corporation (Nasdaq: ONMD) (the “OneMedNet,” the “Company,” “we,” “us” or “our”), a leading provider of regulatory decision-grade, AI-ready Real-World Data (RWD), today announced a strategic collaboration with Navidence to help research organizations transform rapidly expanding healthcare data into clear, actionable real-world evidence.

What This Collaboration Means for the Pharma Market

Pharmaceutical companies face growing pressure to integrate high-quality RWD for regulatory submissions, post-market surveillance, and AI model training. Navidence’s platform enables precise definition of health data needs via Computable Operational Definitions (CODefs)—standardized, executable queries that translate complex study criteria (e.g., patient cohorts by diagnosis, treatment, or outcome) into consistent, computable form across datasets.

This collaboration integrates Navidence’s CODefs with the OneMedNet iRWD™ platform powered by Palantir Foundry.

Key integration elements of the collaboration include:

  • OneMedNet incorporating Navidence CODefs, to enable consistent cohort, endpoint, and criteria definitions.
  • Navidence being integrated with the OneMedNet iRWD™ platform for life sciences, to enable rapid discovery of fit-for-purpose multimodal datasets, streamlining study design regulatory / commercial evidence generation.

Key Potential Benefits of the Collaboration to Our Products and Stakeholders

  • Efficiency Gains: Align CODefs with available RWD in near real-time to accelerate study ideation-to-execution and reduce mismatches / rework.
  • Cost Savings: Expected to enable precise data matching to avoid over-procuring data sets or pursuing infeasible studies, optimizing R&D budgets.
  • Regulatory and Compliance Edge: Combine OneMedNet’s de-identification expertise and Navidence’s standardized definitions to better meet FDA, EMA, and payer requirements for RWE.
  • Innovation in Therapeutic Areas: Particularly valuable in complex fields like precision medicine, where imaging RWD (e.g., MRIs, CT scans) combined with CODefs can reveal nuanced insights into disease progression or treatment efficacy.

Expanding Commercial Opportunity

Real-World Data has long been available, but missing efficient, standardized, and scalable access to Real-World Data.

This collaboration is intended to directly advance OneMedNet’s life sciences strategy by addressing core industry demands of faster, more precise and usable data for pharmaceutical and CRO customers, along with expanded opportunities in the rapidly growing RWD market (valued at approximately $1.88 billion in 2025 and projected to reach $6.37 billion by 2034 at 14.54% CAGR),1 enabling access to precisely defined, fit for purpose datasets across:

  • Drug development and Life sciences research
  • AI model training and validation
  • Health economics and outcomes research (HEOR)
  • Regulatory-grade evidence generation
  • Value-based healthcare analytics

As regulators and payers increasingly require robust real-world evidence, we believe that combining large-scale multimodal data infrastructure with computable definitions positions both companies—and their customers—at the forefront of data transformation.

“Healthcare organizations today have access to more data than ever before and turning that data into reliable evidence requires both scale and precision,” said Aaron Green, CEO & President of OneMedNet. “By combining OneMedNet’s multimodal real-world data platform with Navidence’s computable definitions, we can help researchers identify the right data faster and design studies that deliver high impact evidence.”

“Computable Operational Definitions (CODefs) provide the foundation for consistent and reproducible research independent of the data source,” said Aaron Kamauu, Navidence. “By integrating our content with the OneMedNet iRWD™ platform, researchers can discover precisely defined cohorts and datasets that accelerate study development and improve consistency across clinical research.”

  1. https://www.precedenceresearch.com/real-world-data-rwd-market

About Navidence Inc.

Navidence is a technology company that helps healthcare and life sciences organizations design and assess the use of real-world data in clinical research studies and clinical trials. Through its platform and Computable Operational Definitions (CODefs), Navidence enables consistent, transparent, and reproducible analysis of complex real-world data to support smarter research and better patient outcomes. To learn more about Navidence, visit www.navidence.com and follow us on LinkedIn.

About OneMedNet Corporation

OneMedNet is revolutionizing how the world unlocks Real-World Data (RWD), harnessing the untapped potential of over 2,130 healthcare sites through its iRWD™ platform. This isn’t just data—it’s the lifeblood of innovation, from de-identified medical imaging to electronic health records, fueling breakthroughs for drugmakers, medical device pioneers, and AI visionaries. With a network spanning rare diseases, oncology, cardiology, and beyond, OneMedNet delivers precision insights that redefine patient care and power the next wave of healthcare disruption.

Beyond healthcare OneMedNet’s proprietary AI anonymizes data for industries like finance, retail, and telecom, unlocking endless possibilities—rigorously testing production system upgrades, de-risking complex projects, and securely sharing sensitive data by stripping out personal information.

Learn more at www.onemednet.com.

Cautionary Note Regarding Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. All statements other than statements of historical facts contained in this press release are forward-looking statements. These statements include, but are not limited to, statements regarding our products, plans and strategies (including the expected benefits of the collaboration with Navidence), and our ability to achieve our operational strategies.

Forward-looking statements are based on information available at the time those statements are made and were based on current expectations as well as the beliefs and assumptions of management as of that time with respect to future events. These statements are subject to risks and uncertainties, many of which involve factors or circumstances that are beyond our control. These risks and uncertainties include, but are not limited to: our ability to change the direction of OneMedNet; our ability to keep pace with new technology and changing market needs; the competitive environment of our business; risks inherent with investing in Digital Assets, including Digital Asset’s volatility; our ability to implement our Digital Asset treasury strategy and its effects on our business; and the other risks described in our most recent Annual Report on Form 10-K and our subsequent filings with the Securities and Exchange Commission. Except as required by law, we do not undertake any obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future developments, or otherwise.

OneMedNet Contacts:
Michael Wong, VP Marketing
Email: michael.wong@onemednet.com

SOURCE: ONEMEDNET CORPORATION


FAQ

What did OneMedNet (ONMD) announce on March 18, 2026?

OneMedNet announced a strategic collaboration with Navidence to integrate CODefs into its iRWD™ platform. According to the company, the deal links Navidence computable definitions with OneMedNet infrastructure to speed cohort discovery and improve dataset consistency for life sciences customers.

How will Navidence CODefs integration with OneMedNet iRWD affect pharmaceutical study design?

The integration aims to enable consistent, computable cohort and endpoint definitions across datasets for study design. According to the company, CODefs plus iRWD should reduce mismatches, accelerate ideation‑to‑execution and streamline selection of fit‑for‑purpose multimodal data for trials and studies.

What operational benefits does the OneMedNet and Navidence collaboration claim for ONMD customers?

The collaboration is said to deliver efficiency gains and cost savings by improving precise data matching and reducing rework. According to the company, this should optimize R&D budgets and speed access to usable multimodal real‑world datasets like imaging and clinical records.

Does the OneMedNet–Navidence deal affect regulatory‑grade real‑world evidence for ONMD clients?

The companies expect the integration to strengthen regulatory and compliance readiness for RWE submissions. According to the company, combining de‑identification, multimodal data, and CODefs can better meet FDA, EMA and payer requirements for reproducible evidence.

How does the collaboration expand OneMedNet's commercial opportunity and market context for ONMD?

The partnership targets faster, standardized access to RWD across drug development, AI training, HEOR and value‑based analytics. According to the company, the RWD market was about $1.88 billion in 2025 and projected to reach $6.37 billion by 2034, presenting growth opportunities.
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