Outlook Therapeutics Names Greg DiPasquale Chief Commercial Officer
Outlook plans to make its FDA-approved wet AMD treatment available to eligible U.S. patients before the end of 2026.
Sentiment and the balance of points
Rhea-AI Sentiment reads the wording of the document, how positive or negative its language is on a 1 to 5 scale. The balance of points shown with the takes weighs what the document actually discloses, so the two can disagree, for example when a trial that missed its main goal is described in upbeat language.
Rhea-AI Summary
Outlook Therapeutics (OTLK) named Greg DiPasquale Chief Commercial Officer to lead its commercial functions as it prepares for LYTENAVA’s U.S. launch. The company plans to make LYTENAVA (bevacizumab-vikg), an FDA-approved ophthalmic formulation of bevacizumab for wet age-related macular degeneration, available to eligible U.S. patients before the end of 2026.
DiPasquale joined Outlook in December 2025 as Head of Commercial for LYTENAVA. His responsibilities include market access, commercial operations, marketing, sales and reimbursement. He brings more than 30 years of commercial leadership experience, including nearly two decades in eye care. LYTENAVA will be his fifth retina launch, following BEOVU at Novartis, the EYLEA prefilled syringe and EYLEA HD at Regeneron, and the TRIESENCE relaunch at Harrow.
How this balance works
Rhea-AI gives every point it takes from this document a weight. Minor counts 1, Moderate 3 and Major 9, so one Major point outweighs several Minor ones. The bar adds up the weights on each side, and when neither side holds more than 65% of the total the balance reads Mixed.
It reads the document as published, with the same rules for every company, and it does not look at what the market expected or at how the stock traded, so a point can be objectively good on a day the stock falls.
Rhea-AI Sentiment measures something else, the tone of the wording.
Hollow bars mark forward-looking points. How the balance works
Positive
- Moderate point. Forward-looking: it has not happened yet and may not happen.LYTENAVA’s U.S. commercial availability is planned for eligible patients before the end of 2026.
Negative
- None.
News Explained
Outlook reports that commercial launch of LYTENAVA (bevacizumab gamma) has commenced in Germany, Austria and the U.K.; the product is therefore beyond authorization and in commercial rollout in those named markets.
Key Terms
monoclonal antibody medical
vascular endothelial growth factor medical
intravitreal injections medical
endophthalmitis medical
AI-generated analysis. How Rhea-AI works. Not financial advice.
Veteran retina commercial leader, who has helped launch BEOVU®, EYLEA® and EYLEA® HD, to lead U.S. commercialization of LYTENAVA™ (bevacizumab-vikg)
ISELIN, N.J., Oct. 09, 2026 (GLOBE NEWSWIRE) -- Outlook Therapeutics, Inc. (Nasdaq: OTLK), a biopharmaceutical company focused on the development and commercialization of LYTENAVA™ (bevacizumab-vikg, bevacizumab gamma) for the treatment of retinal diseases, today announced Greg DiPasquale as Chief Commercial Officer. Mr. DiPasquale, who joined Outlook in December 2025 as Head of Commercial for LYTENAVA™, will lead all commercial functions as the Company prepares to make LYTENAVA, the first and only FDA-approved ophthalmic formulation of bevacizumab for the treatment of wet age-related macular degeneration (wet AMD), available to eligible patients in the United States before the end of 2026.
Mr. DiPasquale brings more than 30 years of commercial leadership experience, including nearly two decades in eye care and multiple product launches in retina. LYTENAVA will be the fifth retina launch of his career, following BEOVU® (brolucizumab) at Novartis, the EYLEA® prefilled syringe and EYLEA® HD at Regeneron, and the TRIESENCE® relaunch at Harrow.
Most recently, he served as Senior Vice President and Head of Commercial at Harrow, where he led the commercial organization for the company's branded ophthalmic pharmaceutical portfolio. Before that, he was National Business Director for EYLEA at Regeneron, leading national sales for the product's largest indications and its national strategic accounts within a portfolio generating approximately
“Greg has spent his career putting experienced teams in front of retina specialists at the moments that matter most, and he has already built the foundation of our commercial organization. As we move from approval to launch, his leadership and his relationships across the retina community will be central to bringing LYTENAVA to physicians and patients,” said Bob Jahr, Chief Executive Officer of Outlook Therapeutics.
“Several years ago, while working with higher-priced branded agents, I saw the opportunity to bring an FDA-approved bevacizumab option to patients, providers and payers,” said Mr. DiPasquale. “I have been impressed by this team's grit and perseverance in bringing LYTENAVA to approval, and I wanted to be part of making an immediate impact. In my career, I've seen companies that watch it happen, let it happen, or make it happen. Outlook Therapeutics is going to make it happen.”
Mr. DiPasquale's will lead the commercialization teams including market access, commercial operations, marketing, sales, and reimbursement.
Mr. DiPasquale holds a Bachelor of Business Administration in Marketing and Human Resources from Ohio University and an Executive MBA from Kent State University. He has also served as Executive in Residence and faculty lecturer at the Ohio University College of Business, where he sits on the Executive Advisory Board.
About LYTENAVA™ (bevacizumab-vikg, bevacizumab gamma)
LYTENAVA™ is an ophthalmic formulation of bevacizumab produced in the United States for the treatment of wet AMD. In the United States, LYTENAVA (bevacizumab-vikg) is the only ophthalmic formulation approved by the FDA. LYTENAVA (bevacizumab gamma) is also the subject of a centralized Marketing Authorization granted by the European Commission in the EU and Marketing Authorization granted by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK for the treatment of adults with wet AMD. In certain European Union Member States, LYTENAVA must receive pricing and reimbursement approval before it can be sold.
Bevacizumab-vikg (bevacizumab gamma in the EU and UK) is a recombinant humanized IgG1 monoclonal antibody specific to human vascular endothelial growth factor (VEGF). Bevacizumab binds VEGF and prevents the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells. LYTENAVA binds to all isoforms of VEGF-A, thereby preventing interaction with receptors VEGFR-1 and VEGFR-2. By inhibiting VEGF-A, LYTENAVA suppresses endothelial cell proliferation, neovascularization, and vascular permeability. Inhibition of such activity targets a pathophysiologic process that contributes to vision loss.
Important Safety Information and Indication
LYTENAVA (bevacizumab-vikg) is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with neovascular (wet) age-related macular degeneration (nAMD).
Contraindications
LYTENAVA is contraindicated in patients with ocular or periocular infections, in patients with active intraocular inflammation, and in patients with a known hypersensitivity to bevacizumab products or any of the ingredients in LYTENAVA. Hypersensitivity reactions may manifest as severe intraocular inflammation.
Warnings and Precautions
Intravitreal injections have been associated with endophthalmitis and retinal detachments. Proper aseptic injection technique must always be used when administering LYTENAVA. In addition, patients should be monitored following the injection to permit early treatment should an infection occur.
Increases in intraocular pressure have been noted post-injection (up to 60 minutes) while being treated with LYTENAVA. Monitor intraocular pressure prior to and following intravitreal injection with LYTENAVA and manage appropriately.
Although there was a low rate of arterial thromboembolic events (ATEs) observed in the LYTENAVA clinical trials, there is a potential risk of ATEs following intravitreal use of VEGF inhibitors. ATEs are defined as nonfatal stroke, nonfatal myocardial infarction, or vascular death (including deaths of unknown cause).
Adverse Reactions
The most common adverse reactions (≥
You are encouraged to report side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report side effects to Outlook Therapeutics at 1-833-999-OTLK (6855).
Please see the full U.S. Prescribing Information for LYTENAVA here.
About Outlook Therapeutics, Inc.
Outlook Therapeutics is a biopharmaceutical company focused on the development and commercialization of LYTENAVA (bevacizumab-vikg (U.S.), bevacizumab gamma (E.U.)). LYTENAVA is the only ophthalmic formulation of bevacizumab to receive U.S. FDA approval and European Commission and MHRA Marketing Authorization for the treatment of wet AMD. Outlook Therapeutics commenced commercial launch of LYTENAVA (bevacizumab gamma) in Germany, Austria, and the UK as a treatment for wet AMD.
Forward-Looking Statements
This press release contains statements that may or are considered “forward-looking statements”. All statements other than statements of historical facts are “forward-looking statements,” including those relating to future events. In some cases, you can identify forward-looking statements by terminology such as “anticipate,” “believe,” “can,” “could,” “continue,” “expect,” “may,” “on track,” “plan,” “potential,” “target,” “will,” or “would”, the negative of terms like these or other comparable terminology, and other words or terms of similar meaning. These include, among others, express or implied discussions regarding the Company’s planned launch of LYTENAVA in the United States and other jurisdictions and the timing thereof; expectations concerning potential revenue generation from sales of LYTENAVA; expectations surrounding market adoption of LYTENAVA; expectations regarding the potential impact of LYTENAVA in the retina community; Outlook Therapeutics’ development or future revenue plans for LYTENAVA generally; and other statements that are not historical fact. Although Outlook Therapeutics believes that it has a reasonable basis for the forward-looking statements contained herein, they are based on current expectations about future events affecting Outlook Therapeutics and are subject to risks, uncertainties, and factors relating to its operations and business environment, all of which are difficult to predict and many of which are beyond its control. These risk factors include those risks associated with developing and commercializing pharmaceutical product candidates, risks in obtaining necessary regulatory approvals, the content and timing of decisions by regulatory bodies, as well as those risks detailed in Outlook Therapeutics’ filings with the Securities and Exchange Commission (the SEC), including the Current Report on Form 8-K filed with the SEC on August 12, 2026 and the Quarterly Report on Form 10-Q for the quarter ended June 30, 2026, and future reports Outlook Therapeutics files with the SEC, which include uncertainty of market conditions and future impacts related to macroeconomic factors, including as a result of the ongoing overseas conflicts, tariffs, and trade tensions, fluctuations in interest rates and inflation, and potential future bank failures on the global business environment. These risks may cause actual results to differ materially from those expressed or implied by forward-looking statements in this press release. All forward-looking statements included in this press release are expressly qualified in their entirety by the foregoing cautionary statements. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. Outlook Therapeutics does not undertake any obligation to update, amend, or clarify these forward-looking statements, whether as a result of new information, future events, or otherwise, except as may be required under applicable securities law.
Investor Inquiries:
Jenene Thomas
Chief Executive Officer
JTC Team, LLC
T: 908.824.0775
OTLK@jtcir.com
FAQ
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Who is Outlook Therapeutics’ new Chief Commercial Officer?
Greg DiPasquale is Outlook Therapeutics’ new Chief Commercial Officer. He joined the company in December 2025 as Head of Commercial for LYTENAVA and will lead its commercial functions.