Palo Alto Networks Secures the AI Agent Revolution with the Launch of Prisma AIRS 2.0

Rhea-AI Summary

Palo Alto Networks (NASDAQ: PANW) on October 28, 2025 launched Prisma AIRS 2.0, a major platform upgrade that completes native integration of the acquired Protect AI and delivers end-to-end AI security across the AI application lifecycle.

Key features include AI Agent Security for real-time protection and discovery of sanctioned and shadow agents, AI Red Teaming with an autonomous continuous program using over 500 specialized attacks, and AI Model Security for deep architectural analysis detecting backdoors, data poisoning, and software dependencies. Prisma AIRS 2.0 is available today.

Insights

AI Security Strategist

Palo Alto Networks launches Prisma AIRS 2.0 to provide end-to-end AI security across agents and models, shipping immediately.

Palo Alto Networks bundles deep model inspection, real-time agent defense, and continuous autonomous red teaming into a single platform that claims to inventory agents (including "Shadow AI"), run over 500 specialized attacks, and list a model's architecture, datasets, licenses, and dependencies. The product positions itself as a full‑lifecycle security control for enterprises adopting AI and is stated as "available today" on October 28, 2025.

The platform's effectiveness depends on integration fidelity, detection accuracy, and how enterprise controls map to customer environments; continuous red teaming and real‑time defenses must avoid false positives that could disrupt operations. The announcement cites adoption in finance, healthcare, and government but offers no measured metrics of efficacy or independent validation, so claims should be treated as vendor disclosures rather than proven outcomes.

Watch for independent validation of the red‑teaming coverage, documented detection rates for prompt injection and model backdoors, and third‑party attestations of integration with governance workflows; near‑term signals may appear around the October 28, 2025 Ignite event and early customer case studies published in the following quarters.

Securing every layer of enterprise AI, from autonomous agents to the models that power them

SANTA CLARA, Calif., Oct. 28, 2025 /PRNewswire/ -- Palo Alto Networks (NASDAQ: PANW), the global cybersecurity leader, today announced Prisma® AIRS™ 2.0, a major platform upgrade that completes the native integration of the recently acquired Protect AI to deliver the industry's most comprehensive AI security platform. This release directly confronts a critical enterprise challenge: 78% of organizations are transforming with AI, but only a staggering 6% have the guardrails to do so securely. Prisma AIRS 2.0 meets this urgent demand by providing customers with end-to-end protection across the entire AI application lifecycle, securing everything from autonomous agents to the models themselves.

Anand Oswal, Executive Vice President of Network Security, Palo Alto Networks
"AI is transforming every enterprise, creating extraordinary opportunities and new risks. Prisma AIRS 2.0 bridges that gap, uniting deep model inspection, real-time agent defense, and continuous red teaming in a single platform. We're redefining what it means to secure AI at scale by turning security into an accelerator for innovation, not an obstacle. This marks the continuation of our rapid innovation in AI security as we advance new capabilities to defend against the threats of tomorrow."

Prisma AIRS 2.0 delivers comprehensive end-to-end AI security, seamlessly connecting deep AI agent and model inspection in development with real-time agent defense at production runtime. The platform, continuously validated by autonomous AI red teaming, secures all interactions between AI models, agents, data, and users. This gives enterprises the confidence to discover, assess, and protect their entire AI ecosystem, accelerating secure innovation. Already trusted by global leaders in finance, healthcare, and government, Prisma AIRS 2.0 provides visibility, control, and confidence at scale through three enhanced security modules:

• AI Agent Security: Securing the Autonomous Workforce. Provides real-time, in-line defense against prompt injections, tool misuse, and malicious agent behavior. Prisma AIRS discovers and inventories every AI agent in use – sanctioned or unsanctioned ("Shadow AI") giving the visibility and control needed to secure the explosion of AI agents.
• AI Red Teaming: Continuous, Autonomous Vulnerability Hunting. Addresses the new, dynamic attack surface of Generative AI applications. Uses an autonomous, continuous, and context-aware agentic approach and over 500 specialized attacks to proactively find vulnerabilities in enterprise AI systems before they can be exploited. While others offer periodic testing, Prisma AIRS delivers a persistent, automated red team that thinks like a real adversary.
• AI Model Security: Shielding Open-Source Deployment. Performs a deep architectural analysis of the model itself to find threats traditional scanners can't see. It can detect sophisticated, AI-native threats like architectural backdoors, data poisoning, and malicious code hidden within the model layers. AI Model Security provides a complete "list of ingredients" for enterprise AI, including the model's architecture, training datasets, open-source licenses, and all software dependencies. This provides unparalleled visibility for AI model governance, risk, and compliance.

Harshul Joshi, Principal, Cyber, Data & Tech Risk, PwC US
"The rapid adoption of generative AI is creating a new, complex threat surface for every enterprise. Our strategic alliance with Palo Alto Networks is designed to address this head-on. By fusing PwC's deep AI risk expertise, governance frameworks, and security advisory services with the technological power of their platforms, particularly Prisma AIRS, we offer our customers a unified platform approach to secure their AI deployments. This is no longer about point solutions; it's about providing the full-lifecycle, 'secure-by-design' assurance and managed defense required for our clients to innovate with AI, confidently and at scale."

Securing the Future: Defending Against Threats of Tomorrow
With Prisma AIRS 2.0 setting the standard for AI security today, Palo Alto Networks is already looking ahead to the challenges of tomorrow. The company continues to drive AI innovation at an accelerated pace, strategically engineering its solutions to protect against tomorrow's threats. This vision stretches from securing new application modalities like Cortex^® AgentiX™ for the autonomous workforce, to ensuring safety at the endpoint with secure browsers, and looking ahead to computational risks like quantum readiness. By delivering the most complete, natively integrated platforms, Palo Alto Networks is setting the new benchmark for AI defense, enabling enterprises to accelerate adoption with confidence and ensuring their digital future is secure.

Prisma AIRS 2.0 is available today. To learn more, read the blog and register for Ignite: What's Next on Tuesday, October 28, at 9 a.m. PT. Visit our official news center for the latest announcements, news and developments from Ignite: What's Next.

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About Palo Alto Networks
As the global AI and cybersecurity leader, Palo Alto Networks (NASDAQ: PANW) is dedicated to protecting our digital way of life via continuous innovation. Trusted by more than 70,000 organizations worldwide, we provide comprehensive AI-powered security solutions across network, cloud, security operations and AI, enhanced by the expertise and threat intelligence of Unit 42. Our focus on platformization allows enterprises to streamline security at scale, ensuring protection fuels innovation. Explore more at www.paloaltonetworks.com.

Palo Alto Networks, Prisma, Prisma AIRS, and the Palo Alto Networks logo are trademarks of Palo Alto Networks, Inc. in the United States and in jurisdictions throughout the world. All other trademarks, trade names, or service marks used or mentioned herein belong to their respective owners.

 

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SOURCE Palo Alto Networks, Inc.

FAQ

What is Prisma AIRS 2.0 and when did Palo Alto Networks (PANW) launch it?

Prisma AIRS 2.0 is an end-to-end AI security platform from Palo Alto Networks that launched on October 28, 2025.

How does Prisma AIRS 2.0 secure AI agents and what threats does it address for PANW customers?

The AI Agent Security module provides real-time, in-line defense against prompt injections, tool misuse, and malicious agent behavior, and inventories sanctioned and shadow AI agents.

What does Prisma AIRS 2.0's AI Red Teaming offer and how extensive is its testing capability?

AI Red Teaming runs continuous autonomous vulnerability hunting using a context-aware agentic approach and over 500 specialized attacks to find generative-AI vulnerabilities before exploitation.

What model-level protections does Prisma AIRS 2.0 provide to enterprises using PANW solutions?

AI Model Security performs deep architectural analysis to detect architectural backdoors, data poisoning, and malicious code, and inventories model architecture, training datasets, open-source licenses, and dependencies.

Does Prisma AIRS 2.0 integrate recent Palo Alto Networks acquisitions?

Yes. Prisma AIRS 2.0 completes the native integration of the recently acquired Protect AI into the platform.

Is Prisma AIRS 2.0 available now for customers of Palo Alto Networks (PANW)?

Yes. The company states that Prisma AIRS 2.0 is available today and provides resources including a blog and Ignite session on October 28, 2025.