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Pacira BioSciences Debuts Inspiring New Film Highlighting One Patient’s Journey to Pain Relief and Innovation in Care at BIO 2025

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Pacira BioSciences (NASDAQ: PCRX) premiered a new film at BIO 2025 titled 'The Next Frontier: Mark & Leah's Story,' produced by BBC StoryWorks Commercial Productions. The film chronicles former tennis player Mark Allen's journey from opioid dependency following knee injuries to successful recovery through non-opioid pain management solutions. The story showcases how Mark, with support from his nurse wife Leah, transformed his life using alternative pain therapies, enabling him to open a tennis academy and enjoy time with his grandchildren. The film debuts amid concerning statistics, with CDC reporting 54,743 opioid-related deaths in 2024. Chronic pain affects 82 million Americans and costs the U.S. up to $635 billion annually, exceeding the combined costs of cancer and heart disease, highlighting the urgent need for innovative non-opioid pain management solutions.
Pacira BioSciences (NASDAQ: PCRX) ha presentato in anteprima al BIO 2025 un nuovo film intitolato 'La nuova frontiera: la storia di Mark e Leah', prodotto da BBC StoryWorks Commercial Productions. Il film racconta il percorso di Mark Allen, ex tennista, dalla dipendenza da oppioidi a seguito di infortuni al ginocchio, fino al recupero grazie a soluzioni di gestione del dolore non oppioidi. La storia mostra come Mark, con il sostegno della moglie infermiera Leah, abbia trasformato la sua vita utilizzando terapie alternative per il dolore, permettendogli di aprire un'accademia di tennis e di trascorrere momenti con i suoi nipoti. Il film debutta in un contesto preoccupante: secondo il CDC, nel 2024 si sono registrati 54.743 decessi correlati agli oppioidi. Il dolore cronico colpisce 82 milioni di americani e costa agli Stati Uniti fino a 635 miliardi di dollari all'anno, superando i costi combinati di cancro e malattie cardiache, sottolineando l'urgenza di soluzioni innovative per la gestione del dolore non oppioide.
Pacira BioSciences (NASDAQ: PCRX) estrenó en BIO 2025 un nuevo film titulado 'La próxima frontera: la historia de Mark y Leah', producido por BBC StoryWorks Commercial Productions. La película narra el viaje del extenista Mark Allen desde la dependencia de opioides tras lesiones en la rodilla hasta una recuperación exitosa mediante soluciones de manejo del dolor sin opioides. La historia muestra cómo Mark, con el apoyo de su esposa enfermera Leah, transformó su vida usando terapias alternativas para el dolor, lo que le permitió abrir una academia de tenis y disfrutar tiempo con sus nietos. El film se presenta en medio de estadísticas preocupantes: el CDC reporta 54,743 muertes relacionadas con opioides en 2024. El dolor crónico afecta a 82 millones de estadounidenses y cuesta a EE.UU. hasta 635 mil millones de dólares anuales, superando los costos combinados del cáncer y enfermedades cardíacas, destacando la urgente necesidad de soluciones innovadoras para el manejo del dolor sin opioides.
Pacira BioSciences(NASDAQ: PCRX)는 BIO 2025에서 BBC StoryWorks Commercial Productions가 제작한 '다음 경계: 마크와 리아의 이야기'라는 새 영화를 처음 공개했습니다. 이 영화는 전 테니스 선수 마크 앨런이 무릎 부상 후 오피오이드 의존에서 벗어나 비오피오이드 진통 관리 솔루션을 통해 성공적으로 회복하는 과정을 담고 있습니다. 마크가 간호사인 아내 리아의 지원으로 대체 진통 치료법을 활용해 삶을 변화시키고 테니스 아카데미를 열어 손주들과 시간을 보내는 모습을 보여줍니다. 이 영화는 2024년 CDC가 보고한 54,743건의 오피오이드 관련 사망 통계가 우려되는 가운데 공개되었습니다. 만성 통증은 8,200만 미국인에게 영향을 미치며 연간 최대 6,350억 달러의 비용이 발생하는데, 이는 암과 심장병의 합산 비용을 초과해 혁신적인 비오피오이드 진통 관리 솔루션의 긴급한 필요성을 강조합니다.
Pacira BioSciences (NASDAQ : PCRX) a présenté en avant-première au BIO 2025 un nouveau film intitulé « La prochaine frontière : l'histoire de Mark et Leah », produit par BBC StoryWorks Commercial Productions. Le film retrace le parcours de Mark Allen, ancien joueur de tennis, de sa dépendance aux opioïdes suite à des blessures au genou à sa guérison réussie grâce à des solutions de gestion de la douleur sans opioïdes. L'histoire montre comment Mark, avec le soutien de sa femme infirmière Leah, a transformé sa vie en utilisant des thérapies alternatives contre la douleur, ce qui lui a permis d'ouvrir une académie de tennis et de profiter de moments avec ses petits-enfants. Ce film est présenté dans un contexte préoccupant : selon le CDC, 54 743 décès liés aux opioïdes ont été recensés en 2024. La douleur chronique touche 82 millions d'Américains et coûte aux États-Unis jusqu'à 635 milliards de dollars par an, dépassant les coûts combinés du cancer et des maladies cardiaques, soulignant l'urgence de solutions innovantes pour la gestion de la douleur sans opioïdes.
Pacira BioSciences (NASDAQ: PCRX) präsentierte auf der BIO 2025 einen neuen Film mit dem Titel ‚Die nächste Grenze: Mark & Leahs Geschichte‘, produziert von BBC StoryWorks Commercial Productions. Der Film erzählt die Geschichte des ehemaligen Tennisspielers Mark Allen, der nach Knieverletzungen von einer Opioidabhängigkeit zur erfolgreichen Genesung durch nicht-opioide Schmerztherapien überging. Die Geschichte zeigt, wie Mark mit Unterstützung seiner Krankenschwester-Ehefrau Leah sein Leben durch alternative Schmerztherapien veränderte, eine Tennisakademie eröffnete und Zeit mit seinen Enkeln genießen konnte. Der Film feiert Premiere vor dem Hintergrund besorgniserregender Zahlen: Laut CDC gab es 2024 54.743 opioidbedingte Todesfälle. Chronische Schmerzen betreffen 82 Millionen Amerikaner und kosten die USA jährlich bis zu 635 Milliarden Dollar – mehr als die kombinierten Kosten von Krebs und Herzkrankheiten – was den dringenden Bedarf an innovativen nicht-opioiden Schmerzmanagementlösungen unterstreicht.
Positive
  • Film showcases successful patient outcomes using Pacira's non-opioid pain management solutions
  • Partnership with prestigious BBC StoryWorks enhances company visibility and credibility
  • Addresses large market opportunity with 82 million Americans affected by chronic pain
Negative
  • None.

- Produced for Pacira by BBC StoryWorks Commercial Productions, The Next Frontier: Mark & Leah’s Story Highlights the Impact of Non-Opioid Solutions -

BRISBANE, Calif., June 18, 2025 (GLOBE NEWSWIRE) -- Pacira BioSciences, Inc. (NASDAQ: PCRX), the industry leader in the delivery of innovative, non-opioid pain therapies to transform the lives of patients, today announced the debut of a powerful new film spotlighting the journey of a couple who, after navigating the complexities of acute and chronic pain—and the opioid reliance that often accompanies them—discovered the value of non-opioid treatment options. The film premiered today at the Biotechnology Innovation Organization (BIO) International Convention 2025 in Boston as part of The Next Frontier digital series produced by BBC StoryWorks Commercial Productions.

Titled The Next Frontier: Mark & Leah’s Story, the film tells the deeply personal and inspiring path of former competitive tennis player Mark Allen. After struggling with knee injuries and developing an opioid dependency as a result of his pain management treatment, Mark and his wife Leah came to understand the importance of exploring alternative approaches. Drawing on her background as a nurse, Leah helped guide their journey toward non-opioid therapies that ultimately transformed Mark’s recovery, enabling him to return to the court, open a tennis academy, and reclaim his life.

Now grandparents, they say their greatest reward is being able to enjoy time with their grandchildren, free from pain and dependency. Their story highlights the critical importance of patients knowing they have pain management options beyond opioids, and how a well-thought-out recovery plan can restore not only physical function but the moments that matter most.

“We were honored when BBC StoryWorks approached us to be part of this film,” said Frank D. Lee, chief executive officer of Pacira BioSciences. “Given our unwavering commitment to putting patients at the center of everything we do, sharing the Allens’ story was especially meaningful. We are incredibly grateful to Mark and Leah for allowing us to highlight the real-world impact of non-opioid pain management.”

According to the Centers for Disease Control and Prevention, the U.S. witnessed approximately 80,391 drug overdose deaths in 2024, with opioid-related deaths decreasing to 54,743. Despite this progress, the opioid crisis continues to exact a steep toll. Chronic pain, a key driver of opioid reliance, affects an estimated 82 million Americans and costs the U.S. up to $635 billion each year—more than the combined costs of cancer and heart disease. Yet, investment in novel pain treatments has declined sharply in recent years, underscoring the critical need for innovative, non-opioid therapies like those featured in Mark and Leah’s story

The Next Frontier series explores the role of biotechnology in addressing some of the world’s most pressing challenges, from public health to environmental sustainability, and is available globally on BBC.com.

About Pacira
Pacira delivers innovative, non-opioid pain therapies to transform the lives of patients. Pacira has three commercial-stage non-opioid treatments: EXPAREL® (bupivacaine liposome injectable suspension), a long-acting local analgesic currently approved for infiltration, fascial plane block, and as an interscalene brachial plexus nerve block, an adductor canal nerve block, and a sciatic nerve block in the popliteal fossa for postsurgical pain management; ZILRETTA® (triamcinolone acetonide extended-release injectable suspension), an extended-release, intra-articular injection indicated for the management of osteoarthritis knee pain; and iovera®º, a novel, handheld device for delivering immediate, long-acting, drug-free pain control using precise, controlled doses of cold temperature to a targeted nerve. The Company is also advancing the development of PCRX-201 (enekinragene inzadenovec), a novel, locally administered gene therapy with the potential to treat large prevalent diseases like osteoarthritis. To learn more about Pacira, visit www.pacira.com.

Forward-Looking Statements
Any statements in this press release about Pacira’s future expectations, plans, trends, outlook, projections and prospects, and other statements containing the words “believes,” “anticipates,” “plans,” “estimates,” “expects,” “intends,” “may,” “will,” “would,” “could,” “can” and similar expressions, constitute forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and the Private Securities Litigation Reform Act of 1995, including, without limitation, statements related to: the settlement described herein, ‘5x30’, our growth and business strategy; our future outlook, our intellectual property and patent terms, our growth and future operating results and trends, our strategy, plans, objectives, expectations (financial or otherwise) and intentions, future financial results and growth potential, including our plans with respect to the repayment of our indebtedness, anticipated product portfolio, development programs, development of products, strategic alliances and other statements that are not historical facts. For this purpose, any statement that is not a statement of historical fact should be considered a forward-looking statement. We cannot assure you that our estimates, assumptions and expectations will prove to have been correct. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including risks relating to, among others: the failure to realize the anticipated benefits and synergies from the acquisition of GQ Bio Therapeutics GmbH; risks associated with acquisitions, such as the risk that the acquired businesses will not be integrated successfully, that such integration may be more difficult, time-consuming or costly than expected or that the expected benefits of the transaction will not occur; our manufacturing and supply chain, global and U.S. economic conditions (including inflation and rising interest rates), and our business, including our revenues, financial condition, cash flow and results of operations; the success of our sales and manufacturing efforts in support of the commercialization of EXPAREL, ZILRETTA and iovera°; the rate and degree of market acceptance of EXPAREL, ZILRETTA and iovera°; the size and growth of the potential markets for EXPAREL, ZILRETTA and iovera° and our ability to serve those markets; our plans to expand the use of EXPAREL, ZILRETTA and iovera° to additional indications and opportunities, and the timing and success of any related clinical trials for EXPAREL, ZILRETTA and iovera°; the commercial success of EXPAREL, ZILRETTA and iovera°; the related timing and success of U.S. Food and Drug Administration supplemental New Drug Applications and premarket notification 510(k)s; the related timing and success of European Medicines Agency Marketing Authorization Applications; our plans to evaluate, develop and pursue additional product candidates utilizing our proprietary multivesicular liposome (“pMVL”) drug delivery technology; the approval of the commercialization of our products in other jurisdictions; clinical trials in support of an existing or potential pMVL-based product; our commercialization and marketing capabilities; our ability to successfully complete capital projects; the outcome of any litigation; the recoverability of our deferred tax assets; assumptions associated with contingent consideration payments; assumptions used for estimated future cash flows associated with determining the fair value of the Company; the anticipated funding or benefits of our share repurchase program; and factors discussed in the “Risk Factors” of our most recent Annual Report on Form 10-K and in other filings that we periodically make with the Securities and Exchange Commission (the “SEC”). In addition, the forward-looking statements included in this press release represent our views as of the date of this press release. Important factors could cause actual results to differ materially from those indicated or implied by forward-looking statements, and as such we anticipate that subsequent events and developments will cause our views to change. Except as required by applicable law, we undertake no intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, and readers should not rely on these forward-looking statements as representing our views as of any date subsequent to the date of this press release.

These forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance or achievements to differ materially from those expressed or implied by these statements. These factors include the matters discussed and referenced in the “Risk Factors” of our most recent Annual Report on Form 10-K and in other filings that we periodically make with the SEC.



Investor Contact:
Susan Mesco, (973) 451-4030
susan.mesco@pacira.com

Media Contact:
Sara Marino, (973) 370-5430
sara.marino@pacira.com

FAQ

What is the new film released by Pacira BioSciences (PCRX) at BIO 2025?

The film is 'The Next Frontier: Mark & Leah's Story,' produced by BBC StoryWorks Commercial Productions, showcasing a former tennis player's journey from opioid dependency to recovery through non-opioid pain management.

How many Americans are affected by chronic pain according to Pacira's (PCRX) press release?

According to the press release, chronic pain affects an estimated 82 million Americans and costs the U.S. up to $635 billion annually.

What was the number of opioid-related deaths in 2024 according to the CDC?

According to the CDC data cited in the press release, there were 54,743 opioid-related deaths in 2024.

What is Pacira BioSciences' (PCRX) role in pain management?

Pacira BioSciences is the industry leader in delivering innovative, non-opioid pain therapies aimed at transforming patients' lives.
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