PepGen Inc Stock Price, News & Analysis

PepGen Inc. (Nasdaq: PEPG), a biotechnology company focused on oligonucleotide therapies, announced its participation in the 2023 American Academy of Neurology Annual Meeting from April 22-27 in Boston. The company will feature two oral and two poster presentations, highlighting advancements in treatments for Myotonic Dystrophy Type 1 (DM1) and Duchenne Muscular Dystrophy (DMD). Ashling Holland, Ph.D., will present preclinical data for DM1 on April 27, while two presentations on DMD will occur on April 23, showcasing results from a Phase 1 study of PGN-EDO51 and a study design for PGN-EDODM1. PepGen aims to revolutionize the treatment landscape for severe neuromuscular diseases through its Enhanced Delivery Oligonucleotide platform, demonstrating a commitment to addressing these critical health challenges.

PepGen Inc. (Nasdaq: PEPG), a clinical-stage biotechnology company, announced that its President and CEO, James McArthur, Ph.D., will present at the 22nd Annual Needham Virtual Healthcare Conference on April 20th, 2023, at 8:00 AM EDT. The presentation will be available for live streaming and will also be archived for one year on the company’s website. PepGen focuses on advancing next-generation oligonucleotide therapies aimed at severe neuromuscular and neurological diseases, utilizing its Enhanced Delivery Oligonucleotide (EDO) platform. This platform leverages over a decade of research to enhance the uptake and efficacy of oligonucleotide therapeutics through cell-penetrating peptides.

PepGen Inc. (Nasdaq: PEPG) reported its financial results for Q4 and full year 2022, highlighting significant advancements in its clinical pipeline. The company generated first-in-human data for PGN-EDO51, targeting Duchenne muscular dystrophy (DMD), and plans to initiate Phase 2 studies in 2023. Financially, PepGen reported a net loss of $69.1 million for 2022, an increase from $27.3 million in 2021. R&D expenses rose to $54.1 million, reflecting heightened clinical activities. The company has $181.8 million in cash, funding operations into early 2025. Overall, PepGen aims to develop transformative therapies for severe neuromuscular diseases.

PepGen Inc. (Nasdaq: PEPG) has presented promising clinical and nonclinical data for its Enhanced Oligonucleotide Delivery (EDO) platform at the MDA Conference in Dallas. The data highlights PGN-EDO51's ability to achieve a 34.9% exon skipping in non-human primates after four monthly doses, significantly higher than the 2.5% observed after a single dose. PepGen plans to initiate the CONNECT1-EDO51 Phase 2 study in DMD patients in the first half of 2023, with results expected in 2024. Additionally, the company aims to start the FREEDOM-DM1 Phase 1 study for myotonic dystrophy type 1 (DM1) patients in 2023, targeting safety and efficacy.