Welcome to our dedicated page for Phio Pharmaceuticals news (Ticker: PHIO), a resource for investors and traders seeking the latest updates and insights on Phio Pharmaceuticals stock.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company whose news flow centers on the development of its INTASYL® gene silencing technology and lead compound PH-762. Company announcements describe INTASYL as a gene silencing platform focused on immuno-oncology therapeutics, with PH-762 targeting the PD-1 gene implicated in various forms of skin cancer.
News about Phio frequently covers clinical trial milestones for PH-762. The company has reported completion of enrollment in its ongoing Phase 1b dose escalation trial (NCT 06014086), interim pathology results in cutaneous squamous cell carcinoma, melanoma, and Merkel cell carcinoma, and safety reviews by its Safety Monitoring Committee. Updates have included detailed response rates, such as complete, near complete, and partial responses based on tumor clearance, as well as statements that no dose-limiting toxicities or clinically relevant treatment-emergent adverse effects were observed in the cohorts reported.
Phio also issues regulatory and development updates, including acceptance by the U.S. Food and Drug Administration of its nonclinical protocol study design for a toxicology study required before a pivotal trial of PH-762. Additional news items describe agreements with a U.S. manufacturer for cGMP clinical supply of PH-762 and progress toward delivering commercially viable drug product.
Investors following PHIO news will also see financing and corporate announcements, such as warrant inducement transactions, cash runway commentary, and board-level changes, including the appointment of a Lead Independent Director. The company regularly participates in investor conferences and scientific meetings, where it presents INTASYL technology and PH-762 data, and has highlighted external recognition such as PH-762 being named “Immunomodulatory Solution of the Year” in the BioTech Breakthrough Awards.
This news page aggregates these clinical, regulatory, financing, and governance updates so readers can track how Phio’s INTASYL platform and PH-762 program are progressing over time.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO), a clinical stage biotechnology company, has announced its participation in the Renmark Financial Communications Virtual Non-deal Roadshow Series. The event will feature a presentation and live Q&A session on Wednesday, October 23, 2024, at 12 PM EDT.
Mr. Robert Bitterman, CEO and Chairman of the Board, will lead the presentation. Phio Pharmaceuticals specializes in INTASYL® siRNA gene silencing technology, designed to enhance immune cells' effectiveness in killing tumor cells.
Stakeholders, investors, and interested individuals are invited to register and attend this live event. A replay will be available on the Renmark Financial Communications Inc. website. To ensure smooth connectivity, attendees are advised to use the latest version of Google Chrome when accessing the registration link.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is presenting data on its INTASYL compound PH-894 at the ASGCT's 2024 Advancing Gene and Cell Therapies for Cancer conference. The presentation focuses on how PH-894 improves the functionality and cytotoxicity of Natural Killer (NK) cells in fighting cancer:
1. PH-894 leads to potent and specific silencing of BRD4 in NK cells without affecting cell viability.
2. It boosts NK cell numbers by enhancing proliferation during ex vivo expansion.
3. PH-894 decreases expression of CD94, an inhibitory receptor, potentially improving cytotoxic potential.
4. It may improve NK cell efficacy in adoptive cell therapies.
5. PH-894 serves as a foundation for future NK cell-based immunotherapies.
The presentation by Melissa Maxwell is scheduled for October 16, 2024, from 8 a.m. to 6:45 p.m. ET in the FDR Ballroom.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announced data showcasing its proprietary INTASYL platform and compounds. INTASYL offers precise targeting by silencing mRNA both intracellularly and extracellularly, enhancing immune responses against cancer. The technology is effective as intratumoral injections and during immune cell expansion for adoptive cell therapy, requiring no special formulations for siRNA delivery.
Key INTASYL compounds include:
- PH-762: Silences PD-1, improving therapeutic efficacy in vivo
- PH-894: Silences BRD4, enhancing tumor cell immunogenicity and inducing apoptosis
- PH-804: Silences TIGIT in NK cells, enhancing activation, cytokine release, and target cell killing
- PH-905: Silences CBLB, increasing NK cell cytotoxicity and proliferation
The data will be presented at the 20th Annual Oligonucleotide Therapeutics Society (OTS) Meeting in Montreal on October 8th.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO), a clinical stage biotechnology company, has announced its participation in the Renmark Financial Communications Virtual Non-Deal Roadshow Series. The company's CEO and Chairman of the Board, Robert Bitterman, will present on Wednesday, October 9, 2024, at 2 PM EDT.
Phio Pharmaceuticals specializes in INTASYL® siRNA gene silencing technology, designed to enhance the effectiveness of immune cells in killing tumor cells. Stakeholders, investors, and interested individuals are invited to attend this live virtual event.
To participate, attendees should register through the provided link and use the latest version of Google Chrome for optimal connectivity. A replay of the event will be available on the Renmark Financial Communications website.
Phio Pharmaceuticals (NASDAQ: PHIO) announced its upcoming presentation at the American Society of Gene & Cell Therapy's 2024 Advancing Gene + Cell Therapies for Cancer conference. The event will be held virtually and in Philadelphia on October 16-17, 2024.
The presentation will focus on Phio's INTASYL compound PH-894, which targets BRD4 to enhance Natural Killer (NK) cell-based immunotherapy. Specifically, PH-894 silences BRD4 and enhances activation and proliferation of NK cells for Adoptive Cell Therapy (ACT).
Presentation details:
- Title: INTASYL PH-894: Targeting BRD4 to Enhance NK Cell-Based Immunotherapy
- Presenter: Melissa Maxwell
- Date: October 16, 2024
- Time: 8 a.m. - 6:45 p.m. ET
- Location: FDR Ballroom, Wyndham Hotel, Philadelphia Historic District
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) announced it will present data on its INTASYL technology platform at the 20th Annual Oligonucleotide Therapeutics Society (OTS) Meeting in Montreal from October 6th-9th. The presentation, titled 'INTASYL Self-Delivering RNAi: a Flexible Platform for Cancer Treatment', will focus on how INTASYL can enhance ex vivo expansion processes to improve functionality and outcomes of adoptive cell therapies like NK, TIL, or CAR-T.
INTASYL's advantage lies in its simplified chemical composition, designed to reduce toxicity and improve tolerability and efficacy in therapeutic development. The poster presentation (Number P180) will be given by Melissa Maxwell on October 8th from 3:45-6:45 PM at the Centre Mont-Royal in Montreal.
Phio Pharmaceuticals (NASDAQ: PHIO), a clinical stage biotechnology company, has announced its participation in the Renmark Financial Communications Virtual Non-Deal Roadshow Series. The event is scheduled for Tuesday, September 24, 2024, at 12 PM EDT.
Mr. Robert Bitterman, CEO and Chairman of the Board, will present on behalf of Phio Pharmaceuticals. The company specializes in INTASYL® siRNA gene silencing technology, designed to enhance immune cells' effectiveness in killing tumor cells.
Stakeholders, investors, and interested individuals are invited to register and attend this live event. A replay will be available on the Renmark Financial Communications Inc. website. Attendees are advised to use the latest version of Google Chrome for optimal connectivity.
Phio Pharmaceuticals (NASDAQ: PHIO) announced a presentation at the 9th Annual CAR-TCR Summit in Boston, MA, showcasing its INTASYL self-delivering RNAi technology. The presentation, titled 'INTASYL Self-Delivering RNAi: A Flexible Platform to Improve Adoptive Cell Therapy,' will be given by Melissa Maxwell on September 17th. INTASYL is designed to enhance cell potency and yield in Adoptive Cell Therapy, potentially offering a more effective approach for cancer treatment. The technology aims to make immune cells more effective in killing tumor cells through gene silencing. This presentation highlights Phio's efforts to advance its innovative platform in the competitive field of cell therapy.
Phio Pharmaceuticals (NASDAQ: PHIO), a clinical stage biotech company, will participate in the H.C. Wainwright 26th Annual Global Investment Conference from September 9-11, 2024, in New York City. CEO Robert Bitterman will present on the company's INTASYL siRNA gene silencing technology, which aims to enhance immune cells' ability to kill tumor cells.
The presentation will cover:
- INTASYL technology overview
- Associated patents and intellectual property
- Ongoing Phase 1b clinical trial of PH-762, Phio's lead INTASYL compound
Phio's presentation will be streamed online starting September 9th at 7:00 AM ET. The management team will also be available for one-on-one meetings during the conference.
Phio Pharmaceuticals (NASDAQ: PHIO), a clinical stage biotech company specializing in INTASYL® siRNA gene silencing technology, has announced its participation in the Renmark Financial Communications Virtual Non-Deal Roadshow Series. The event is scheduled for Thursday, September 5, 2024, at 12 PM EDT.
Robert Bitterman, CEO and Chairman of the Board, will present on behalf of Phio Pharmaceuticals. The presentation will include a live Q&A session. Stakeholders, investors, and interested individuals are invited to register and attend this live event. A replay will be available on the Renmark Financial Communications website.
Phio's INTASYL® technology is designed to enhance the effectiveness of immune cells in killing tumor cells, positioning the company at the forefront of innovative cancer treatments.