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Pliant Therapeutics Announces Upcoming Presentations at the 2025 American Thoracic Society International Conference

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Pliant Therapeutics (Nasdaq: PLRX) has announced its participation in the 2025 American Thoracic Society (ATS) International Conference in San Francisco from May 16-21, 2025. The company will present three scientific works, including:

1. A featured oral presentation by Dr. Johanna Schaub on Bexotegrast's antifibrotic activity in ILD subtypes (May 19, 2:15-4:15 PM PT)

2. A poster presentation by Dr. Richard Ahn on plasma proteome analysis of ILD subtypes (May 21, 8:15-10:15 AM PT)

3. A poster by Dr. Mahru An on single-cell profiling of Bexotegrast's antifibrotic effects (May 21, 8:15-10:15 AM PT)

All presentations will be available for registered conference attendees and later on Pliant's website.

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SOUTH SAN FRANCISCO, Calif., April 07, 2025 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX) today announced that the Company will present three scientific posters at the upcoming 2025 American Thoracic Society (ATS) International Conference, taking place in San Francisco, California from May 16-21, 2025.

The following abstracts are posted on ATS 2025’s online itinerary planner for registered users.

Pliant was selected for a featured oral presentation as part of the ATS 2025 Mini Symposiums program.

Title: Characterizing the Antifibrotic Activity of Bexotegrast on Distinct Fibroblast Populations in PCLS From Multiple ILD Subtypes
Presenter: Johanna Schaub, Ph.D., Director of Translational Sciences at Pliant Therapeutics
Oral Presentation: 9696
Session B98: Cellular interactions and signaling networks in pulmonary fibrosis (mini symposium)
Date: Monday, May 19, 2025
Presentation Time: 2:15 p.m. – 4:15 p.m. Pacific Time

Title: Plasma Proteome Analysis Reveals Shared and Unique Biomarkers of ILD Subtypes
Presenter: Richard Ahn, Ph.D., Senior Scientist II at Pliant Therapeutics
Poster: 12006
Session D29: From bench to bedside: unraveling pulmonary fibrosis through cellular communication and molecular pathways
Date: Wednesday, May 21, 2025
Presentation Time: 8:15 a.m. – 10:15 a.m. Pacific Time

Title: Single-Cell Profiling Demonstrates the Antifibrotic Effects of Bexotegrast on Pathologic Lung Cell Populations in the Presence and Absence of Background Therapy
Presenter: Mahru An, Ph.D., Principal Scientist at Pliant Therapeutics
Poster: 12106
Session D29: From bench to bedside: unraveling pulmonary fibrosis through cellular communication and molecular pathways
Date: Wednesday, May 21, 2025
Presentation Time: 8:15 a.m. – 10:15 a.m. Pacific Time

Posters will be available to view during the ATS Conference, Sunday, May 18 - Wednesday, May 21 during the above times for registered users and on the Presentations page of the company website at www.PliantRx.com.

About Pliant Therapeutics, Inc.

Pliant Therapeutics is a late-stage biopharmaceutical company and leader in the discovery and development of novel therapeutics for the treatment of fibrotic diseases. Pliant's lead product candidate, bexotegrast (PLN-74809), is an oral, small molecule, dual selective inhibitor of αvß6 and αvß1 integrins that is in development in the lead indication for the treatment of idiopathic pulmonary fibrosis, or IPF. Bexotegrast has received Fast Track Designation and Orphan Drug Designation from the U.S. Food and Drug Administration (FDA) and Orphan Drug Designation from the European Medicines Agency in IPF. Pliant is conducting a Phase 1 study for PLN-101095, a small molecule, dual-selective inhibitor of αvß8 and αvß1 integrins, that is being developed for the treatment of solid tumors. In addition, Pliant has received regulatory clearance for the conduct of a Phase 1 study of PLN-101325, a monoclonal antibody agonist of integrin α7β1 targeting muscular dystrophies.

For additional information, please visit: www.PliantRx.com. Follow us on social media XLinkedIn, and Facebook.

Investor and Media Contact:

Christopher Keenan
Vice President, Investor Relations and Corporate Communications
Pliant Therapeutics, Inc.
ir@pliantrx.com


FAQ

What will Pliant Therapeutics present at ATS 2025 regarding Bexotegrast?

Pliant will present research on Bexotegrast's antifibrotic activity in ILD subtypes and its effects on pathologic lung cell populations, through both an oral presentation and a poster session.

When are PLRX's presentation times at the 2025 ATS Conference?

The oral presentation is on May 19 (2:15-4:15 PM PT), and two poster presentations are scheduled for May 21 (8:15-10:15 AM PT).

How many scientific presentations will PLRX deliver at ATS 2025?

Pliant Therapeutics will deliver three scientific presentations: one featured oral presentation and two poster presentations.

Where can investors view PLRX's ATS 2025 conference presentations?

The presentations will be available to registered conference attendees during ATS 2025 and later on Pliant's website at www.PliantRx.com.

What research topics will PLRX present at the 2025 ATS Conference?

PLRX will present research on Bexotegrast's antifibrotic activity, plasma proteome analysis of ILD subtypes, and single-cell profiling of antifibrotic effects.
Pliant Therapeutics, Inc.

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