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Polaryx Therapeutics To Participate In The 25th Annual Needham Virtual Healthcare Conference

Polaryx Therapeutics (Nasdaq: PLYX) will participate in the 25th Annual Needham Virtual Healthcare Conference, hosting one-on-one investor meetings April 13–16, 2026 and a group presentation on April 16, 2026 at 10:15 a.m. ET.

Sentiment and the balance of points

Rhea-AI Sentiment reads the wording of the document, how positive or negative its language is on a 1 to 5 scale. The balance of points shown with the takes weighs what the document actually discloses, so the two can disagree, for example when a trial that missed its main goal is described in upbeat language.

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Polaryx Therapeutics (Nasdaq: PLYX) will participate in the 25th Annual Needham Virtual Healthcare Conference, hosting one-on-one investor meetings April 13–16, 2026 and a group presentation on April 16, 2026 at 10:15 a.m. ET.

Live webcasts and archived replays will be available in the Investors Relations "News and Events" section at the company website.

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Argus Apr 1 session
+0.53% close to close Open Argus
Details

News Market Reaction – PLYX

On Apr 1, the day this news came out, PLYX closed 0.53% above the previous close.

Data tracked by StockTitan Argus for the Apr 1 session.

Key Figures

Share price: $7.56 Market cap: $312,939,193 Shares outstanding: 47,343,297 shares +5 more
Share price
$7.56
Pre-news close, PLYX share price
Market cap
$312,939,193
Pre-news equity value based on current price
Shares outstanding
47,343,297 shares
Common shares outstanding as of Feb 1, 2026 (10-K)
Major holder stake
22,744,796 shares (48.0%)
Group led by Mstone and Alex Keun Mo Yang (Schedule 13D)
Aggregate purchase price
$3,000,513
Total cost for major holder’s currently owned shares (Schedule 13D)
Insider purchase
2,867 shares at $2.7871
CFO open-market buy on Feb 18, 2026 (Form 4)
CFO direct holdings
228,225 shares
CFO stake after Feb 18, 2026 purchase (Form 4)
Conference presentation time
10:15 a.m. ET
Group presentation at 25th Annual Needham Virtual Healthcare Conference

Historical Context

5 past events · Latest: Mar 17
5 events
  1. Mar 17

    Regulatory designation

    24h Move
    -0.9%

    FDA Fast Track designation for PLX-200 in CLN2 disease.

  2. Mar 12

    Community engagement

    24h Move
    -19.3%

    Expanded engagement with Krabbe community and SOTERIA trial update.

  3. Feb 27

    Awareness initiative

    24h Move
    -4.4%

    Rare Disease Day activities and reaffirmed commitment to LSD patients.

  4. Feb 17

    Trial operations update

    24h Move
    +64.3%

    CRO selected for SOTERIA Phase 2 basket trial of PLX-200.

  5. Feb 10

    Preclinical data presentation

    24h Move
    -24.1%

    Preclinical PLX-200 data for Krabbe disease presented at WORLDSymposium.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Key Terms

lysosomal storage disorders
1 terms
lysosomal storage disorders medical
"developing novel, disease-modifying therapies for rare, pediatric lysosomal storage disorders"
A group of inherited conditions where cells cannot break down and clear certain molecules, like a clogged recycling center inside cells causing harmful buildup that damages organs and the nervous system. Investors care because these disorders create clear targets for specialized treatments, often qualify for orphan-drug incentives and accelerated review, and can drive focused clinical programs and high-value niche markets if therapies prove safe and effective.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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PARAMUS, NJ, April 01, 2026 (GLOBE NEWSWIRE) -- Polaryx Therapeutics, Inc. (Nasdaq: PLYX), a clinical-stage biotechnology company developing novel, disease-modifying therapies for rare, pediatric lysosomal storage disorders (“LSDs”), announces that members of the executive team will be participating in the 25th Annual Needham Virtual Healthcare Conference.

Format: Polaryx management will host one-on-one investor meetings as well as a group presentation

Dates:

One‑on‑one meetings: Monday, April 13, 2026 through Thursday, April 16, 2026

Group presentation: Thursday, April 16, 2026 at 10:15 a.m. ET

To schedule a meeting, please contact your Needham & Company, LLC representative.

Live webcasts of the presentations will be available under “News and Events” in the Investors Relations section of the Company’s website at https://investors.polaryx.com/. Replays of the webcasts will be archived and available following the events. 

About Polaryx Therapeutics

Polaryx Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing patient-friendly small molecule and gene therapy treatments for rare orphan lysosomal storage disorders (LSDs). Founded in 2014, Polaryx seeks to deliver safe, effective, and patient-friendly treatments that address the underlying pathophysiology of these catastrophic diseases and their significant unmet need. Our approach integrates small molecule therapies, including a combination therapy, and a gene therapy, positioning us to potentially address both the genetic and downstream pathological features of LSDs. Our small molecule drug candidates share similar modes of action that have been demonstrated to address lysosomal dysfunction, neuroinflammation, and neuronal loss in our validated animal models that closely mimic human clinical phenotypes. Our most advanced product candidate, PLX-200, targets several LSDs and we intend to launch SOTERIA, a Phase 2 basket trial, to evaluate PLX-200’s safety and efficacy. For more information, please visit www.polaryx.com.

Forward-Looking Statements

Certain statements in this press release may constitute “forward-looking statements” within the meaning of the federal securities laws, including, but not limited to, statements regarding: Polaryx’s clinical development plans for PLX-200, including the timing for initiation of the SOTERIA trial. Words such as “may,” “might,” “will,” “objective,” “intend,” “should,” “could,” “can,” “would,” “expect,” “believe,” “design,” “estimate,” “predict,” “potential,” “develop,” “plan” or the negative of these terms, and similar expressions, or statements regarding intent, belief, or current expectations, are forward-looking statements. While Polaryx believes these forward-looking statements are reasonable, undue reliance should not be placed on any such forward-looking statements, which are based on information available to the company on the date of this release. These forward-looking statements are based upon current estimates and assumptions and are subject to various risks and uncertainties (including, without limitation, those set forth in Polaryx’s filings with the U.S. Securities and Exchange Commission (the SEC), many of which are beyond the company’s control and subject to change. Actual results could be materially different. Risks and uncertainties include: global macroeconomic conditions and related volatility, expectations regarding the initiation, progress, and expected results of Polaryx’s clinical trials; expectations regarding the timing, completion and outcome of Polaryx’s clinical trials; the timing or likelihood of regulatory filings and approvals; liquidity and capital resources; and other risks and uncertainties identified in Polaryx’s Registration Statement on Form S-1, as amended, filed with the SEC on January 27, 2026 and subsequent disclosure documents Polaryx may file with the SEC. Polaryx claims the protection of the Safe Harbor contained in the Private Securities Litigation Reform Act of 1995 for forward-looking statements. Polaryx expressly disclaims any obligation to update or alter any statements whether as a result of new information, future events or otherwise, except as required by law.

Media Contact:
CORE IR
(212) 655-0924
media@polaryx.com

Investor Contact:
CORE IR
(212) 655-0924
inestor@polaryx.com



FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

When will Polaryx Therapeutics (PLYX) present at the Needham Virtual Healthcare Conference in April 2026?

Polaryx will give a group presentation on April 16, 2026 at 10:15 a.m. ET. According to Polaryx Therapeutics, management will also hold one-on-one investor meetings April 13–16, 2026 to engage with investors.

How can investors watch Polaryx Therapeutics (PLYX) presentation at the April 2026 Needham conference?

Investors can watch a live webcast via the company Investors Relations site under News and Events. According to Polaryx Therapeutics, replays will be archived and available after the events for later viewing.

Can investors schedule one-on-one meetings with Polaryx Therapeutics (PLYX) at the Needham conference?

Yes, one-on-one investor meetings are scheduled April 13–16, 2026 and are available through Needham representatives. According to Polaryx Therapeutics, contact your Needham & Company representative to request a meeting.

Where will archived replays of Polaryx Therapeutics (PLYX) Needham presentations be posted?

Replays will be archived in the Investors Relations "News and Events" section on the company website. According to Polaryx Therapeutics, archived webcasts will remain available following the conference events.

What topics will Polaryx Therapeutics (PLYX) management cover at the Needham Virtual Healthcare Conference?

Management will present company updates and engage with investors through meetings and a group presentation. According to Polaryx Therapeutics, the format includes one-on-one meetings plus a group presentation on April 16, 2026.

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