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ProMIS Neurosciences Inc. reports clinical-stage biotechnology developments around antibody therapeutics and vaccines that target toxic misfolded proteins in neurodegenerative diseases. Company news centers on PMN310, its lead humanized monoclonal antibody for Alzheimer’s disease, the PRECISE-AD clinical program, FDA Fast Track designation, biomarker research involving plasma pTau, and scientific publications or conference presentations tied to Alzheimer’s disease, ALS, and Parkinson’s disease.
Updates also cover operating and financial results, governance matters, shareholder votes, capital-structure actions, and investor conference participation. The company’s research disclosures emphasize its proprietary discovery platform and selective targeting of disease-specific toxic protein species rather than broader amyloid plaque binding.
ProMIS Neurosciences (TSX: PMN, Nasdaq: PMN) announced key developments related to its Alzheimer's disease candidate, PMN310, including the completion of preclinical studies and preparations for an IND submission to the FDA within 60 days. The company reported a significant increase in R&D expenses, totaling $16.1 million for 2022, up from $4.6 million in 2021. General and Administrative expenses rose to $7.3 million, compared to $3.7 million in the previous year. The net loss for 2022 was $18.1 million, reflecting the company's investment in advancing its drug development pipeline.
ProMIS Neurosciences Inc. (TSX: PMN, Nasdaq: PMN), a biotechnology firm focused on antibody therapeutics for neurodegenerative diseases, has announced that CEO Gail Farfel, Ph.D., will present at the Oppenheimer 33rd Annual Conference on March 13, 2023, at 12:30 p.m. ET. The presentation will be webcasted and available on ProMIS’ website for 30 days following the event.
The company specializes in targeting toxic misfolded proteins linked to conditions such as Alzheimer’s disease, amyotrophic lateral sclerosis, and multiple system atrophy. ProMIS employs proprietary platforms to discover novel antibody therapeutics.
ProMIS Neurosciences (TSX: PMN) announced a $7.4 million private placement and appointed Gail Farfel, Ph.D. as its CEO as of September 19, 2022. The company is progressing toward an investigational new drug (IND) submission for PMN310, targeting Alzheimer’s disease, with plans to enroll the first subject in a Phase 1a trial in the first half of 2023. Financial highlights for Q3 2022 include a net loss of $6.0 million and research expenses of $4.6 million, up from $0.8 million year-over-year. Cash reserves decreased to $4.0 million.
ProMIS Neurosciences Inc. (Nasdaq: PMN) has closed a fully subscribed private placement of 1,383,755 Units at US$5.40 each, raising gross proceeds of US$7,472,277. Each Unit consists of a Common Share and a quarter Warrant, with each full Warrant exercisable at US$7.50 for five years. Proceeds will fund the first-in-human study of lead candidate PMN310 in 2023, pending FDA approval, while also supporting IP expansion and working capital. ProMIS focuses on developing antibody therapeutics for neurodegenerative diseases like Alzheimer’s, ALS, and MSA.
ProMIS Neurosciences (Nasdaq: PMN) has appointed Gail M. Farfel, Ph.D., as its new Chief Executive Officer, effective September 19, 2022. With over 25 years of experience in neurology drug development, Dr. Farfel aims to lead ProMIS towards becoming a clinical-stage biotechnology company with multiple product opportunities. The company achieved significant milestones in the past 18 months, including a successful Nasdaq listing and the IND submission for their lead Alzheimer’s drug, PMN310, expected by year-end.