Pmv Pharmaceuticals, Inc. Stock Price, News & Analysis

PMV Pharmaceuticals, Inc. (PMVP) reported promising preclinical data on its investigational drug PC14586 at the AACR Annual Meeting 2021. This tumor-agnostic small molecule targets p53 mutations, with enrollment in its Phase 1/2 trial proceeding as planned. Financial results for Q1 2021 reveal a net loss of $11.6 million and operational cash usage of $12.9 million. Cash reserves decreased to $348.4 million from $361.4 million. The company also expanded its Board and Scientific Advisory Board with leading experts in precision oncology.

PMV Pharmaceuticals (Nasdaq: PMVP) announced that CEO David H. Mack, Ph.D., will present at the Bank of America Healthcare Conference on May 13, 2021, at 12:30 PM ET. The presentation will discuss PMV's pioneering work in precision oncology and its focus on developing small molecule therapies targeting p53 mutants, which are prevalent in about half of all cancers. The company will also engage in one-on-one meetings with investors during the conference. A replay of the presentation will be accessible on PMV's website.

PMV Pharmaceuticals presents promising preclinical data on PC14586, a small molecule p53 reactivator targeting the Y220C mutation. The drug demonstrated robust tumor regression in mouse models with once daily oral dosing. Notably, PC14586 selectively stabilizes the p53 Y220C mutant, restoring its activity without affecting wild-type or other mutant forms. Enrollment is ongoing for a Phase 1/2 clinical trial in patients with advanced solid tumors featuring this specific mutation, with pharmacodynamic biomarkers developed for future clinical use.

PMV Pharmaceuticals (Nasdaq: PMVP) announced the appointment of Charles M. Baum, M.D., Ph.D., to its Board of Directors. Dr. Baum is recognized for his contributions to precision oncology, with a strong track record in developing oncology portfolios. CEO David Mack expressed optimism about Baum's expertise enhancing their lead candidate, PC14856, a p53 reactivator. Dr. Baum's experience includes leadership roles at Mirati Therapeutics and Pfizer, where he developed key oncology drugs. PMV focuses on therapies targeting p53 mutations, pivotal in cancer treatment.

PMV Pharmaceuticals announced its participation at the AACR Annual Meeting 2021 from April 10-15, where it will present on PC14586, the first orally bioavailable small molecule reactivator of the Y220C mutant p53. This therapy targets a significant mutation found in various cancers, aiming to restore the tumor suppressor function of p53. Details of the presentation include the title, authors, and timing. PMV aims to develop this innovative treatment for patients with advanced solid tumors.

PMV Pharmaceuticals, Inc. (Nasdaq: PMVP) has initiated a Phase 1/2 study of PC14586, targeting advanced solid tumors with a p53 Y220C mutation. The FDA granted Fast Track designation for this investigational therapy. Financially, the company reported a net loss of $34.4 million for 2020, up from $25.4 million in 2019. PMVP ended Q4 2020 with $361.4 million in cash, a significant increase from $101.5 million a year earlier. R&D expenses rose to $23.9 million due to clinical advances, while G&A expenses increased to $11 million as the company expands its public operations.

PMV Pharmaceuticals (Nasdaq: PMVP) announced its participation in the Lung Cancer Panel at the Cowen 41st Annual Health Care Conference from March 1-4, 2021. David H. Mack, Ph.D., CEO, will speak on March 2 at 11:10 AM. PMV Pharma focuses on developing small molecule, tumor-agnostic therapies targeting p53 mutations, prevalent in about half of all cancers. The company's foundation is rooted in over four decades of p53 biology research by co-founder Dr. Arnold Levine.

PMV Pharmaceuticals, Inc. (Nasdaq: PMVP) appointed Dr. Guillermina (Gigi) Lozano to its Scientific Advisory Board, enhancing its expertise in p53 biology. Dr. Lozano, a distinguished geneticist, has made significant contributions to understanding the p53 pathway and its mutations in cancer. Her experience at The University of Texas MD Anderson Cancer Center and recognition from acclaimed scientific organizations underscore her qualifications. This strategic addition could bolster PMV Pharma's efforts in developing small molecule therapies targeting p53 mutations, which are prevalent in nearly half of all cancers.

PMV Pharmaceuticals (Nasdaq: PMVP) has announced that CEO David H. Mack, Ph.D., will present at the Evercore ISI 3rd Annual HealthCONx Conference on December 2, 2020, at 1:00 PM ET. This presentation focuses on the company's pioneering work in precision oncology, targeting p53 mutants, a common mutation in cancer. Interested parties can access the presentation via the company's website. PMV Pharma, based in Cranbury, New Jersey, specializes in tumor-agnostic therapies and is leveraging decades of research in p53 biology.