STOCK TITAN

Prelude Therapeutics Incorporated - PRLD STOCK NEWS

Welcome to our dedicated page for Prelude Therapeutics Incorporated news (Ticker: PRLD), a resource for investors and traders seeking the latest updates and insights on Prelude Therapeutics Incorporated stock.

Prelude Therapeutics Incorporated (Nasdaq: PRLD) is a clinical-stage biopharmaceutical company focused on developing innovative small molecule therapies targeting key mechanisms in cancers with high unmet needs. Founded in 2016 and headquartered in Wilmington, Delaware, the company's mission is to deliver precision oncology treatments that can address the critical pathways in cancer cells.

Prelude's robust pipeline includes several promising drug candidates currently in clinical development:

  • PRT543: This candidate is in Phase 1 clinical trials targeting select solid tumors and myeloid malignancies in patients who are refractory to or intolerant of established therapies.
  • PRT811: Also in Phase 1 trials, PRT811 focuses on solid tumors, including glioblastoma multiforme and primary central nervous system lymphomas.
  • PRT1419: A potent and selective inhibitor of the anti-apoptotic protein MCL1, which is undergoing clinical evaluation for its efficacy and safety in cancer treatment.
  • PRT2527: This highly selective CDK9 inhibitor demonstrates substantial potential in treating solid and hematological malignancies and aims to minimize off-target toxicities.
  • PRT3645: A next-generation CDK4/6 inhibitor that shows promise for better safety, tolerability, and efficacy in various cancers beyond breast cancer.
  • PRT3789: A first-in-class SMARCA2 protein degrader targeting cancers with SMARCA4 mutations.

In recent developments, Prelude has extended its cash runway into 2026 following a successful public offering, raising approximately $113 million in gross proceeds. Their strategic collaboration with AbCellera aims to co-develop innovative antibody drug conjugate therapies, combining AbCellera's antibody discovery platform with Prelude's expertise in medicinal chemistry and drug development.

Prelude's financial strength is evident with cash, cash equivalents, and marketable securities totaling $255 million as of June 30, 2023. Their focused approach on advancing their pipeline and making critical strategic decisions is supported by clinical data showing promising efficacy and safety profiles for their drug candidates, such as PRT2527 and PRT1419. The company's commitment to addressing cancers with high unmet needs positions it as a significant player in precision oncology.

For more detailed information and the latest updates on Prelude Therapeutics' research advancements, financial performance, and strategic initiatives, visit their official website and follow them on LinkedIn and Twitter.

Rhea-AI Summary
Prelude Therapeutics Incorporated (PRLD) reports financial results for 2023 and outlines key objectives for 2024. The company focuses on first-in-class IV SMARCA2 degrader and potentially best-in-class CDK9 inhibitor. A partnership with AbCellera aims to develop precision ADCs. The company has a cash runway into 2026 with $232.9 million in cash. Clinical milestones for 2024 include proof-of-concept data for SMARCA2 degrader and CDK9 inhibitor.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
33.05%
Tags
-
Rhea-AI Summary
Prelude Therapeutics Incorporated (Nasdaq: PRLD) announced a private placement to raise approximately $25 million in gross proceeds, which will be used to fund the advancement of its SMARCA2 portfolio, for working capital, and general corporate purposes. The additional funding is expected to sustain the company's operations until 2026.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-1.79%
Tags
none
-
Rhea-AI Summary
Prelude Therapeutics announces the prioritization of its SMARCA2 degrader and CDK9 inhibitor programs for continued clinical development. The company also enters a partnership with AbCellera to develop precision ADCs. Prelude has a cash runway into 2026 with $230.5 million in cash, cash equivalents, and marketable securities.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
18.82%
Tags
partnership earnings
Rhea-AI Summary
Prelude Therapeutics and AbCellera have announced a multi-year, multi-program partnership to discover, develop, and commercialize novel oncology medicines. The collaboration will focus on up to five programs, with the first program targeting a SMARCA degrader. Prelude will lead clinical development and global commercialization, while AbCellera will lead manufacturing activities.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
18.82%
Tags
partnership
-
Rhea-AI Summary
Prelude Therapeutics to participate in three upcoming healthcare investment conferences
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-4.48%
Tags
conferences
-
Rhea-AI Summary
Prelude Therapeutics reports Q2 2023 financial results and pipeline updates. Recent financing extends cash runway into 2026. Lead programs PRT2527 and PRT1419 show promising clinical safety profiles and target inhibition. PRT3645 and PRT3789 progressing well in Phase 1. Cash, cash equivalents, and marketable securities as of June 30, 2023, were $255.0 million. R&D expense increased to $25.0 million. Net loss for Q2 2023 was $30.4 million.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-3.73%
Tags
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-3.63%
Tags
conferences
-
Rhea-AI Summary
Prelude Therapeutics has announced the pricing of its underwritten public offering, expecting to receive total gross proceeds of approximately $100.0 million. The offering includes 3,048,522 shares of voting common stock, 1,448,222 shares of non-voting common stock, and pre-funded warrants to purchase up to 12,895,256 shares of common stock. The offering is expected to close on May 22, 2023.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-11.43%
Tags
-
Rhea-AI Summary
Prelude Therapeutics has announced an underwritten public offering of $100.0 million of shares of common stock and pre-funded warrants. The proceeds will be used to advance its clinical pipeline and research efforts, as well as for organizational growth and working capital.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-11.43%
Tags
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-2.15%
Tags

FAQ

What is the current stock price of Prelude Therapeutics Incorporated (PRLD)?

The current stock price of Prelude Therapeutics Incorporated (PRLD) is $2.77 as of September 13, 2024.

What is the market cap of Prelude Therapeutics Incorporated (PRLD)?

The market cap of Prelude Therapeutics Incorporated (PRLD) is approximately 171.7M.

What does Prelude Therapeutics Incorporated specialize in?

Prelude Therapeutics specializes in the discovery and development of small molecule therapies targeting key mechanisms in cancers with high unmet needs.

Where is Prelude Therapeutics Incorporated based?

Prelude Therapeutics is based in Wilmington, Delaware.

What are some key drug candidates in Prelude Therapeutics' pipeline?

Some key drug candidates include PRT543, PRT811, PRT1419, PRT2527, PRT3645, and PRT3789.

What is PRT2527?

PRT2527 is a highly selective CDK9 inhibitor demonstrating potential in treating solid and hematological malignancies while minimizing off-target toxicities.

What recent financial achievement has Prelude Therapeutics reported?

Prelude Therapeutics recently raised approximately $113 million in gross proceeds from a public offering, extending their cash runway into 2026.

Who has Prelude Therapeutics partnered with for drug development?

Prelude Therapeutics has partnered with AbCellera to co-develop innovative antibody drug conjugates.

What is PRT3645?

PRT3645 is a next-generation CDK4/6 inhibitor focusing on improved safety, tolerability, and efficacy in various cancers beyond breast cancer.

What is the focus of PRT3789?

PRT3789 is a first-in-class SMARCA2 degrader targeting cancers with SMARCA4 mutations.

What are the financial resources available to Prelude Therapeutics?

As of June 30, 2023, Prelude Therapeutics had cash, cash equivalents, and marketable securities totaling $255 million.

Where can I find more information about Prelude Therapeutics?

For more information, visit Prelude Therapeutics' official website at www.preludetx.com and follow them on LinkedIn and Twitter.

Prelude Therapeutics Incorporated

Nasdaq:PRLD

PRLD Rankings

PRLD Stock Data

171.68M
42.17M
9.07%
94.11%
2.61%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
WILMINGTON