Personalis Stock Price, News & Analysis

Personalis (Nasdaq: PSNL) published new results in Nature Medicine from their TRACERx lung cancer study, conducted with London's Francis Crick Institute and University College London. The study utilized NeXT Personal®, an ultra-sensitive test for detecting circulating tumor DNA (ctDNA) in blood samples.

The research analyzed pre-operative blood samples from 171 early-stage non-small cell lung cancer patients. The test demonstrated 100% detection in non-adenocarcinomas and 81% in lung adenocarcinomas (LUAD). Notably, LUAD patients testing negative for ctDNA pre-surgery showed 100% 5-year survival rates, while ctDNA-positive patients had high relapse risks. Even patients with very low ctDNA levels (below 80 PPM) showed high recurrence risks.

The study highlights NeXT Personal's potential in early lung cancer detection and management, particularly significant given lung cancer's position as the second most common cancer in the U.S., with 238,340 new cases and 127,070 deaths projected for 2023.

Personalis (PSNL) reported preliminary unaudited revenue of approximately $84.6 million for full year 2024, marking a 15% increase from 2023's $73.5 million and exceeding previous guidance of $83.0-84.0 million. The company's pharma tests, services, and enterprise sales revenue grew 20% to $77.2 million, despite a 20% decrease in Natera revenue to $25.4 million.

Fourth quarter 2024 revenue was $16.8 million, down 15% year-over-year, primarily due to declining revenue from Natera and VA MVP. The company delivered 1,441 molecular tests in Q4 2024, up 52% from Q3. Cash position stood at approximately $185.0 million, including a $50 million strategic investment from Merck. The company also secured a long-term commercial collaboration with Moderna.

Personalis (NASDAQ: PSNL) announced two significant agreements: a $50 million investment from Merck through private placement stock purchase at $3.56 per share, and a multi-year extension of its collaboration with Moderna. The investment will give Merck approximately 16.5% ownership stake in Personalis, representing about 14 million shares.

The extended collaboration involves Personalis' ImmunoID NeXT Platform® being used for V940/mRNA-4157, an investigational individualized neoantigen therapy being jointly developed by Merck and Moderna. Personalis has been providing its tumor-profiling platform to both companies since the beginning of the V940/mRNA-4157 clinical development program.

Personalis (Nasdaq: PSNL) and Tempus AI (Nasdaq: TEM) have expanded their commercial relationship to benefit the biopharma industry. Originally agreed upon in November 2023, the collaboration aims to bring ultra-sensitive MRD testing to market. The partnership was launched at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, with Tempus serving as the exclusive commercial diagnostic partner for Personalis' NeXT Personal® Dx. This product is designed for broad patient adoption in breast and lung cancers and immunotherapy monitoring across all solid tumors.

Following a positive market reaction, Tempus will now offer Personalis' NeXT Personal MRD product to pharmaceutical and biotech customers. These customers can bundle MRD testing with other Tempus offerings within a given study. Chris Hall, CEO of Personalis, believes that this expansion will accelerate market penetration and capitalize on new opportunities.

Personalis (Nasdaq: PSNL), a leader in advanced genomics for precision oncology, has announced its participation in two upcoming investor conferences. The company will join the Piper Sandler 36th Annual Healthcare Conference on December 3, 2024, featuring a fireside chat at 12:30 PM ET at The Lotte New York Palace. Additionally, Personalis will participate in TD Cowen's Diagnosing Tomorrow: Tools & Technologies for the Next Decade conference on December 12, 2024, contributing to a panel discussion on 'MRD - The Future Tech Stack' at 1:30 PM ET at One Vanderbilt in New York.

Personalis (PSNL) reported strong Q3 2024 financial results with total revenue of $25.7 million, up 41% year-over-year. Biopharma revenue grew 96% to $15.7 million, while Enterprise revenue decreased 33% to $5.3 million. The company raised approximately $62.2 million through various financing activities, including transactions with Tempus AI and ATM program sales. Cash position stands at $143.7 million, extending runway into H1 2027. The company increased its full-year 2024 revenue guidance to $83-84 million, up from previous $79-81 million, despite reporting a net loss of $39.1 million for Q3.

Personalis, a leading company in advanced genomics for precision oncology, has announced its participation in the Stifel 2024 Healthcare Conference. The company's management team is scheduled to present on Tuesday, November 19, at 10:55 a.m. Eastern Time. The presentation will take place at the Lotte New York Palace Hotel in New York, NY.

Personalis (Nasdaq: PSNL) has scheduled its third quarter 2024 financial results announcement for Wednesday, November 6, 2024. The company will host a conference call and webcast at 2:00 p.m. Pacific Time / 5:00 p.m. Eastern Time on the same day to discuss the results and recent highlights. Investors can join via phone (877-451-6152 domestic, 201-389-0879 international) or through the company's website. A replay will be available and archived online after the call.

Personalis, Inc. (Nasdaq: PSNL) presented compelling data at ESMO 2024 for its NeXT Personal® MRD test. Two studies showcased the test's effectiveness in lung cancer monitoring and immunotherapy response assessment. The TRACERx study, analyzing over 400 NSCLC patients, demonstrated strong detection rates for residual lung cancer post-surgery, with 42% of detections in the ultrasensitive range. The test showed high sensitivity in detecting early-stage recurrence months ahead of imaging. Another study by VHIO, involving 200+ late-stage cancer patients on immunotherapy, revealed that significant ctDNA level decreases correlated with longer overall survival. These findings underscore the importance of ultrasensitive MRD testing in cancer management and therapy response monitoring.