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Protagonist Therapeutics, Inc. (PTGX) announced that its President and CEO, Dinesh V. Patel, Ph.D., will participate in a presentation and host one-on-one meetings with investors at the 42nd Annual J.P. Morgan Healthcare Conference on January 8-11, 2024. The presentation will take place on Tuesday, January 9 at 9:45-10:25 A.M. PST in San Francisco, CA. The event details and webcast link can be found on the company's corporate website.
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Protagonist Therapeutics, Inc. (PTGX) announced it has earned a $10 million milestone payment following the dosing of the third patient in ANTHEM-UC, a Phase 2b trial to evaluate the safety and effectiveness of JNJ-2113 compared with placebo in participants with moderately to severely active ulcerative colitis. With this additional payment, the Company has now earned $60 million in payments in the fourth quarter of 2023 for milestones achieved in the JNJ-2113 Phase 2b and Phase 3 clinical programs led by the Company's collaboration partner, Janssen Biotech, Inc., a Johnson & Johnson company. The Company remains eligible for up to an additional $795 million in other development and sales milestone payments with respect to JNJ-2113 or other licensed IL-23 receptor antagonist oral peptides.
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Protagonist Therapeutics, Inc. (PTGX) presented long-term follow-up data from the REVIVE Phase 2 study and other analyses at the American Society of Hematology 2023 Annual Meeting. The data showed durable hematocrit control, decreased phlebotomy use, long-term tolerability, and no new safety signals in patients with polycythemia vera. Rusfertide, a mimetic of the natural hormone hepcidin, demonstrated potential therapeutic value in treating PV and other diseases.
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Protagonist Therapeutics, Inc. (PTGX) announced the addition of two Phase 3 studies, ICONIC-ADVANCE 1 and ICONIC-ADVANCE 2, evaluating JNJ-2113 in head-to-head comparisons against deucravacitinib in patients with moderate-to-severe psoriasis. The company is eligible to receive a $115 million milestone payment upon achieving co-primary endpoints in any of the studies. JNJ-2113 is a targeted oral peptide designed to selectively block the IL-23 receptor, and the Phase 3 program aims to establish it as the preferred oral treatment option for psoriasis patients. Protagonist has a license and collaboration agreement with Janssen for the development and commercialization of JNJ-2113, earning milestone payments upon successful milestones and eligible for additional development and sales milestone payments. The company also retains upward tiering royalties of 6%-10% for net sales of JNJ-2113.
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Protagonist Therapeutics, Inc. (Nasdaq:PTGX) issued inducement awards to two new employees, granting them options to purchase 50,000 shares of the company's common stock at an exercise price of $16.29. The options vest over a four-year period, with 25% vesting on the first anniversary of hire and the remainder in equal monthly installments over three years. The awards were granted in accordance with the Protagonist Therapeutics Amended and Restated Inducement Plan and approved by the compensation committee as a material inducement to employment.
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Protagonist Therapeutics (Nasdaq:PTGX) ranked in the top 3% of the 2023 Deloitte Technology Fast 500TM, showcasing impressive revenue growth fueled by a novel oral peptide therapeutic program. The company's CEO expressed pride in the recognition and highlighted the dedication of the team and strength of partnerships.
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Protagonist Therapeutics, Inc. announced that five abstracts related to their rusfertide program have been accepted for presentation at the 65th American Society of Hematology Annual Meeting and Exposition. The presentations will cover data on the potential of rusfertide in the treatment of Polycythemia Vera and other disease indications. The company will also present data on the epidemiological aspects of Polycythemia Vera and preclinical data on the treatment of sickle cell disease with a hepcidin mimetic. The presentations are expected to make significant contributions to the field of hematology.
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Protagonist Therapeutics reports positive Phase 2b results for JNJ-2113, an oral IL-23 receptor antagonist peptide drug candidate for plaque psoriasis. The company plans to advance with two Phase 3 studies in psoriasis and a Phase 2b study in ulcerative colitis. Cash runway is forecasted through Q1 2026.
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Protagonist Therapeutics achieves $50 million milestone event in collaboration with Janssen Biotech for the development of JNJ-2113 in psoriasis. The ICONIC Phase 3 program is progressing rapidly, and additional Phase 3 studies are planned for JNJ-2113. ANTHEM UC Phase 2b study for ulcerative colitis is also underway.
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Protagonist Therapeutics, Inc. announced that its CEO will participate in investor conferences this month. The conferences include Guggenheim 5th Annual I&I Conference, J.P. Morgan Equity Opportunities Forum, Truist Securities BioPharma Symposium, and Jefferies London Healthcare Conference. Company presentations will be available on the Protagonist corporate website.
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Protagonist Therapeutics, Inc
Nasdaq:PTGX
PTGX Rankings
PTGX Stock Data
1.53B
40.66M
1.71%
100.41%
5.9%
Pharmaceutical Preparation Manufacturing
Manufacturing
United States of America
NEWARK
About PTGX
protagonist therapeutics is a clinical-stage biopharmaceutical company with a proprietary technology platform which is utilized to discover and develop novel peptide-based drugs to address significant unmet medical needs. its primary focus is on developing potential first-in-class oral targeted therapy-based peptide drugs that work by blocking biological pathways that are currently targeted by marketed injectable antibody drugs. protagonist's initial lead peptide product candidates, ptg-100 and ptg-200, are based on this approach, and the company believes these candidates have the potential to transform the existing treatment paradigm for inflammatory bowel disease (ibd), consisting primarily of ulcerative colitis and crohn's disease. ptg-100, a potential first-in-class oral peptide alpha-4-beta-7 integrin antagonist, is currently in a global phase 2b clinical trial for treatment of moderate-to-severe ulcerative colitis. ptg-200, a first-in-class oral interleukin-23 receptor antagonist