RAPT Therapeutics Reports First Quarter 2025 Financial Results
Rhea-AI Summary
RAPT Therapeutics (NASDAQ: RAPT) reported its Q1 2025 financial results, showing a significant improvement in net loss to $17.2 million compared to $30.5 million in Q1 2024. Research and development expenses decreased to $12.0 million from $24.8 million year-over-year, while G&A expenses slightly decreased to $7.2 million from $7.7 million. The company maintained a strong cash position of $179.3 million as of March 31, 2025.
CEO Brian Wong highlighted progress with RPT904, their food allergy treatment candidate, with plans to initiate a Phase 2b trial in H2 2025. The company is also anticipating clinical data for RPT904 in chronic spontaneous urticaria (CSU) from their partner Jemincare later this year.
Positive
- Net loss improved significantly from $30.5M to $17.2M year-over-year
- Strong cash position of $179.3M as of March 31, 2025
- R&D expenses decreased by 51.6% to $12.0M
- Phase 2b trial for RPT904 in food allergy planned for H2 2025
Negative
- Company continues to operate at a loss ($17.2M in Q1)
- G&A expenses remain relatively high at $7.2M for a clinical-stage company
Insights
RAPT shows 44% smaller loss, pivots resources to RPT904 with solid $179.3M cash position providing ~10 quarters runway.
RAPT Therapeutics delivered significant financial improvement in Q1 2025, with net loss narrowing 43.6% to
G&A expenses also improved marginally, falling
The financial restructuring reflects a calculated pivot toward RPT904 and early-stage programs, while reducing investment elsewhere. This focused approach enhances capital efficiency, particularly critical for clinical-stage biotechs navigating the current challenging funding environment. The substantial cash position provides sufficient runway to reach important clinical milestones that could potentially transform the company's valuation thesis if RPT904 demonstrates compelling efficacy in upcoming trials.
RAPT pivots to promising RPT904 for food allergies and CSU, deprioritizing other programs while advancing toward Phase 2b trial.
The strategic realignment toward RPT904 represents a significant reshaping of RAPT's clinical pipeline. The company is positioning RPT904 as a potential best-in-class therapy for food allergies, a condition affecting approximately 32 million Americans with limited effective treatment options beyond allergen avoidance and emergency medications.
The planned Phase 2b trial initiation in H2 2025 indicates confidence in RPT904's mechanism of action and preliminary clinical profile, though specific efficacy metrics aren't detailed in this release. Food allergies represent an enormous market opportunity with significant unmet needs – current desensitization approaches have limitations in efficacy, safety, and practicality.
Additionally, RAPT is expanding RPT904's potential through exploration in chronic spontaneous urticaria (CSU), a debilitating condition affecting 0.5-1% of the global population. The collaboration with Jemincare, with data expected later this year, provides external validation of RPT904's potential while sharing development costs. CSU represents another substantial market with limited effective treatment options for refractory patients.
The significant reduction in spending on zelnecirnon and tivumecirnon programs suggests a data-driven portfolio prioritization strategy. While the press release doesn't specify the rationale, such reprioritization typically follows careful assessment of clinical data, competitive landscape, and commercial potential. This focused approach aligns with industry best practices for optimizing resource allocation in clinical-stage companies.
SOUTH SAN FRANCISCO, Calif., May 08, 2025 (GLOBE NEWSWIRE) -- RAPT Therapeutics, Inc. (Nasdaq: RAPT) (“RAPT” or the “Company”), a clinical-stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing novel therapies for patients living with inflammatory and immunological diseases, today reported financial results for the first quarter ended March 31, 2025.
“The year is off to a great start. We believe RPT904 has the potential to be a best-in-class option to treat patients with food allergy and are making good progress toward our planned initiation of a Phase 2b trial in the second half of 2025,” said Brian Wong, President and CEO of RAPT. “We are also excited about RPT904's potential as a treatment for patients with chronic spontaneous urticaria (“CSU”) and look forward to clinical data later this year from our partner Jemincare to guide our development strategy in CSU.”
Financial Results for the First Quarter March 31, 2025
Net loss for the first quarter of 2025 was
Research and development expenses for the first quarter of 2025 were
General and administrative expenses for the first quarter of 2025 were
As of March 31, 2025, the Company had cash and cash equivalents and marketable securities of
About RAPT Therapeutics, Inc.
RAPT is a clinical-stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing novel therapies for patients living with inflammatory and immunological diseases. Utilizing our deep and proprietary expertise in immunology, we develop novel therapies that are designed to modulate the critical immune responses underlying these diseases.
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “anticipate,” “estimates,” “expects,” “look forward,” “plans,” “potential” “will” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are intended to identify forward-looking statements. These statements relate to future events and involve known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements to be materially different from any future performances or achievements expressed or implied by the forward-looking statements. Each of these statements is based only on current information, assumptions and expectations that are inherently subject to change and involve a number of risks and uncertainties. Forward-looking statements include, but are not limited to, statements about the therapeutic potential of RPT904, the timing of the initiation of or data from clinical trials, expectations concerning our partnership with Jemincare, the market opportunity for RPT904, and other statements that are not historical fact. Many factors may cause differences between current expectations and actual results, including unexpected or unfavorable safety or efficacy data observed during clinical studies, preliminary data and trends that may not be predictive of future data or results or that may not demonstrate safety or efficacy or lead to regulatory approval, our reliance on our partners and other third parties, clinical trial site activation or enrollment rates that are lower than expected, unanticipated or greater than anticipated impacts or delays due to macroeconomic and geopolitical conditions (including the long-term impacts of ongoing overseas conflicts, tariffs and trade tensions, fluctuations in inflation and interest rates and other economic uncertainty), changes in expected or existing competition, changes in the regulatory environment, the uncertainties and timing of the regulatory approval process and the sufficiency of RAPT’s cash resources. Detailed information regarding risk factors that may cause actual results to differ materially from the results expressed or implied by statements in this press release may be found in RAPT’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 8, 2025 and subsequent filings made by RAPT with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. RAPT disclaims any obligation to update these forward-looking statements, except as required by law.
RAPT Media Contact:
Aljanae Reynolds
areynolds@wheelhouselsa.com
RAPT Investor Contact:
Sylvia Wheeler
swheeler@wheelhouselsa.com
| RAPT THERAPEUTICS INC. STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (In thousands, except share per share data) (Unaudited) | ||||||||
| Three Months Ended March 31, | Three Months Ended March 31, | |||||||
| 2025 | 2024 | |||||||
| Operating expenses: | ||||||||
| Research and development | 12,042 | 24,781 | ||||||
| General and administrative | 7,223 | 7,737 | ||||||
| Total operating expenses | 19,265 | 32,518 | ||||||
| Loss from operations | (19,265 | ) | (32,518 | ) | ||||
| Other income, net | 2,100 | 1,997 | ||||||
| Net loss | $ | (17,165 | ) | $ | (30,521 | ) | ||
| Other comprehensive income (loss): | ||||||||
| Unrealized loss on marketable securities | (15 | ) | (113 | ) | ||||
| Total comprehensive loss | $ | (17,180 | ) | $ | (30,634 | ) | ||
| Net loss per share, basic and diluted | $ | (0.08 | ) | $ | (0.79 | ) | ||
| Weighted average number of shares used in computing net loss per share, basic and diluted | 215,410,253 | 38,625,365 | ||||||
| RAPT THERAPEUTICS, INC. BALANCE SHEETS (In thousands) | ||||||||
| March 31, 2025 | December 31, 2024 | |||||||
| Assets | (Unaudited) | (1) | ||||||
| Current assets: | ||||||||
| Cash and cash equivalents | $ | 60,257 | $ | 169,735 | ||||
| Marketable securities | 119,019 | 61,320 | ||||||
| Prepaid expenses and other current assets | 3,920 | 4,181 | ||||||
| Total current assets | 183,196 | 235,236 | ||||||
| Property and equipment, net | 1,158 | 1,367 | ||||||
| Operating lease right-of-use assets | 2,827 | 3,333 | ||||||
| Other assets | 389 | 389 | ||||||
| Total assets | $ | 187,570 | $ | 240,325 | ||||
| Liabilities and stockholders’ equity | ||||||||
| Current liabilities: | ||||||||
| Accounts payable | $ | 1,295 | $ | 1,275 | ||||
| Accrued expenses | 4,928 | 9,597 | ||||||
| License fees payable | — | 35,000 | ||||||
| Operating lease liabilities, current | 2,315 | 2,422 | ||||||
| Other current liabilities | 140 | 57 | ||||||
| Total current liabilities | 8,678 | 48,351 | ||||||
| Operating lease liabilities, non-current | 1,520 | 2,070 | ||||||
| Total liabilities | 10,198 | 50,421 | ||||||
| Commitments | ||||||||
| Stockholders’ equity: | ||||||||
| Preferred stock | — | — | ||||||
| Common stock | 13 | 13 | ||||||
| Additional paid-in capital | 809,036 | 804,388 | ||||||
| Accumulated other comprehensive income | 35 | 50 | ||||||
| Accumulated deficit | (631,712 | ) | (614,547 | ) | ||||
| Total stockholders’ equity | 177,372 | 189,904 | ||||||
| Total liabilities and stockholders’ equity | $ | 187,570 | $ | 240,325 | ||||
| (1) | The balance sheet for December 31, 2024 has been derived from audited financial statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2024. |
FAQ
What was RAPT Therapeutics' (RAPT) net loss in Q1 2025?
How much cash does RAPT Therapeutics have as of March 2025?
When will RAPT Therapeutics start Phase 2b trials for RPT904?
How did RAPT's R&D expenses change in Q1 2025 compared to Q1 2024?
What are the main therapeutic areas RAPT Therapeutics is focusing on?
