Welcome to our dedicated page for Revelation Biosciences news (Ticker: REVB), a resource for investors and traders seeking the latest updates and insights on Revelation Biosciences stock.
Revelation Biosciences, Inc. (NASDAQ: REVB) is a clinical-stage life sciences company developing Gemini, a proprietary PHAD®-based toll-like receptor 4 (TLR4) agonist designed to rebalance the innate immune response in acute and chronic inflammation-driven diseases. The REVB news feed on Stock Titan aggregates company press releases and related coverage so readers can follow key scientific, clinical, regulatory, and corporate developments.
News about Revelation Biosciences frequently highlights progress across its Gemini programs for acute kidney injury (GEMINI-AKI), chronic kidney disease (GEMINI-CKD), prevention of post-surgical infection (GEMINI-PSI), and treatment of severe burn-related hyperinflammation (GEM-PBI). Updates include clinical milestones such as Phase 1 and Phase 1b data from the PRIME study in stage 3 and 4 CKD patients, where the company has reported safety, reductions in inflammatory activity, and restoration of normal cellular responses to stimuli.
Investors and observers can also find announcements about interactions with the U.S. Food and Drug Administration, including submission and acceptance of an end-of-phase 1 meeting package for Gemini in AKI, as well as manufacturing news such as the start of GMP production of Gemini and placebo to support later-stage randomized, double-blinded, placebo-controlled trials.
Beyond clinical and regulatory updates, the REVB news stream covers financial and corporate actions disclosed by the company, including warrant exercise inducement transactions, special meetings of stockholders to approve share issuances under Nasdaq rules, and inducement equity grants under Nasdaq Listing Rule 5635(c)(4). Bookmark this page to monitor Revelation Biosciences’ ongoing disclosures about Gemini’s development, capital markets activity, and governance events.
Revelation Biosciences Inc. (NASDAQ: REVB) reported its year-end 2022 financial results, showcasing a significant cash increase to $5.3 million, up from $1.3 million in 2021, primarily from a $15.6 million public offering. The company plans to initiate a combined Phase 1a clinical study for REVTx-100 and REVTx-300 in the latter half of 2023, supported by positive preclinical data. Revelation's net loss for 2022 was $10.8 million, or $20.09 per share, an improvement from $12.0 million in 2021, indicating reduced operational expenses. The firm anticipates sufficient funds to support operations through June 2024.
Revelation Biosciences Inc. (NASDAQ: REVB) has appointed Dr. Julia Bohannon and Dr. Antonio Hernandez to its Scientific Advisory Board. Dr. Bohannon, an Associate Professor at Vanderbilt University Medical Center, specializes in immunomodulatory treatments for burn injuries. Dr. Hernandez, also from Vanderbilt, focuses on enhancing innate immunity and developing therapies for critical care patients. Both bring significant expertise and will guide the company's PHAD-based technology for preventing and treating healthcare-associated infections. CEO James Rolke expressed excitement about their contributions to Revelation's ongoing efforts in immunologic therapies.
Revelation Biosciences Inc. (NASDAQ: REVB) announced the closing of a public offering on February 13, 2023, raising approximately $15.6 million. The offering consisted of 2,888,600 common stock shares and 336,400 pre-funded warrants at $4.83 per share. Additionally, warrants to purchase up to 6,450,000 shares were included, with an exercise price of $5.36. The proceeds will fund clinical studies for REVTx-100 and REVTx-300, focusing on surgical site infections and acute kidney injury. The offering was made under registration statements declared effective on February 9, 2023, by the SEC.
Revelation Biosciences Inc. (NASDAQ: REVB) has announced a public offering of 3,225,000 shares priced at $4.83 each, along with warrants to purchase up to 6,450,000 additional shares at an exercise price of $5.36. The gross proceeds are expected to total approximately $15.6 million, intended for advancing the development of their therapies REVTx-100 and REVTx-300, including clinical trials and manufacturing. The offering is anticipated to close around February 13, 2023, pending usual conditions. Roth Capital Partners serves as the sole placement agent.
Revelation Biosciences Inc. (NASDAQ: REVB) reported statistically significant preclinical results for REVTx-300, a potential therapy for acute and chronic kidney disease. In a validated model, treatment with REVTx-300 led to significant reductions in TGF-β and increases in anti-inflammatory markers IL-10, hepcidin, and NGAL. No significant inflammation markers increased, indicating a potential reduction in fibrosis. The company plans to publish these findings in 2023 and is preparing to initiate clinical studies. Positive results were previously reported on October 25, 2022, and November 18, 2022, regarding renal fibrosis reduction.
Revelation Biosciences Inc. (NASDAQ: REVB) announced a 1-for-35 reverse stock split effective February 1, 2023, after stockholder approval. This action aims to increase the per-share market price to comply with NASDAQ's minimum bid requirements. Consequently, the outstanding shares will decrease to approximately 672,460 shares. Additionally, stockholders approved raising the authorized common stock to 500,000,000 shares and ratified Baker Tilly US, LLP as independent public accountants. The reverse split does not change stockholder equity proportions or the par value of the common stock.
Revelation Biosciences Inc. (NASDAQ: REVB) announced a mandatory separation of its trading units on January 13, 2023. Following this, units will cease to trade on the Nasdaq Capital Market. Each unit, consisting of one common stock share and one warrant priced at $11.50, will convert automatically into shares and warrants. Post-separation, common stock and warrants will trade under the symbols 'REVB' and 'REVBW'. Revelation focuses on immunologic therapies for disease prevention and treatment, with several candidates in development, including REVTx-100, REVTx-200, and REVTx-300.
Revelation Biosciences Inc. (NASDAQ: REVB) announced successful exploratory biomarker analyses supporting the clinical development of REVTx-300 for chronic kidney disease (CKD) and acute kidney injury (AKI). A significant 57% reduction in new collagen deposition was observed in preclinical models, indicating a potential for new intellectual property. Plans include initiating a Phase 1a study in early 2023, followed by a Phase 1b study in patients undergoing cardiac surgery. The CEO emphasized the therapeutic potential of modulating the innate immune response for treating inflammatory diseases.
Revelation Biosciences Inc. (NASDAQ: REVB) reported its third quarter 2022 financial results, highlighting key corporate developments. The company completed a $5.0 million public offering and licensed innovative IP for REVTx-100 aimed at healthcare-associated infections. Notably, positive preclinical data for REVTx-300 in kidney-related conditions was announced. As of September 30, 2022, cash and cash equivalents rose to $6.2 million from $1.3 million in 2021. However, the company recorded a net loss of $1.2 million for Q3 2022, down from $3.0 million in Q3 2021, indicating improved financial performance.
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