Rafael Holdings Stock Price, News & Analysis

Rafael Holdings, Inc. (NYSE: RFL) announced a private placement expected to generate gross proceeds of $104.2 million. The company will sell 2,833,426 shares of Class B common stock at $35.00 per share, plus 112,561 shares to an accredited investor at $44.42 per share, the closing price on August 19, 2021. The offering, not registered under the Securities Act, is subject to conditions and is set to close on August 24, 2021. A registration statement will be filed for resales of the securities.

Rafael Holdings, Inc. (NYSE: RFL) announced the addition of three senior executives: Gus Kodersha as Chief Technical Operations Officer, Melissa Lozner as Chief Compliance & Ethics Officer, and Brandi Robinson as Chief Corporate Affairs Officer. This strategic move aims to strengthen the company's leadership as it advances critical Phase 3 clinical trials, particularly for CPI-613® targeting metastatic pancreatic cancer. CEO Ameet Mallik emphasized the new leaders' extensive experience, which is expected to enhance the company’s potential in developing cancer metabolism therapeutics.

Rafael Pharmaceuticals announced positive results from the interim futility analysis of its Phase 3 trial (ARMADA 2000) for CPI-613® (devimistat) in treating relapsed or refractory acute myeloid leukemia (AML). Conducted by an independent Data Monitoring Committee on June 25, 2021, the trial was deemed non-futile, allowing it to continue. The interim analysis involved 142 patients and indicated a predefined response rate threshold was met. Devimistat targets cancer cell energy metabolism, potentially enhancing treatment efficacy while reducing side effects for various cancers.

Rafael Pharmaceuticals announced that data regarding its lead compound, devimistat, will be presented at the 2021 ESMO World Gastrointestinal Congress from June 30 to July 3. This presentation will focus on ongoing trials for devimistat in treating pancreatic and biliary tract cancer. Both cancers have low survival rates, with biliary cancer at 9% and pancreatic cancer at 10.8% over five years. Devimistat targets cancer cell metabolism and may improve treatment outcomes, with pivotal Phase 3 trials already approved by the FDA.

Rafael Pharmaceuticals announced that the FDA has granted orphan drug designation for CPI-613 (devimistat) to treat biliary cancer. This rare form of cancer affects approximately 12,000 people annually in the U.S. Devimistat has also received orphan drug status for pancreatic cancer, AML, and others, totaling seven designations. The company emphasizes the urgent need for effective treatments for rare cancers, as current options have limited response rates. Devimistat targets mitochondrial processes to enhance cancer therapy effectiveness with reduced side effects.

Rafael Holdings, Inc. (NYSE: RFL) and Rafael Pharmaceuticals presented at the Raymond James 2021 Human Health Innovation Conference on June 22, 2021. Key figures included CEO Ameet Mallik and President Sanjeev Luther. The companies are focused on developing novel cancer therapies, particularly through Rafael Pharmaceuticals, which is advancing multiple clinical studies for its lead drug, CPI-613 (devimistat). This includes ongoing Phase 3 trials for metastatic pancreatic cancer and acute myeloid leukemia. The companies aim to create a publicly traded late-stage clinical oncology entity, enhancing their market position.

Rafael Holdings, Inc. (NYSE: RFL) has announced a merger with Rafael Pharmaceuticals, a late-stage oncology firm specializing in cancer metabolism therapeutics. The merger, unanimously approved by both boards, aims to create a publicly traded company focused on innovative cancer treatments. Key figures include Howard Jonas as Chairman and Ameet Mallik as CEO. The merger includes the acquisition of Altira Capital for $30 million and requires a capital raise of at least $50 million. The lead drug, CPI-613 (devimistat), is in Phase 3 trials for metastatic pancreatic cancer, with results expected in Q4 2021.

Rafael Holdings, Inc. (NYSE: RFL) reported Q3 FY 2021 revenue of $1.0 million, down from $1.2 million year-over-year, primarily due to asset sales and reduced parking revenues amid the COVID pandemic. The loss per share was $0.15, compared to $0.14 in the prior year. The company appointed Ameet Mallik as CEO and William Conkling as Chief Commercial Officer. A shelf registration statement for up to $250 million of Class B common stock was filed. Rafael Pharmaceuticals anticipates pivotal trial data for pancreatic cancer in Q4 2021.

Rafael Holdings, Inc. (NYSE: RFL) announced the appointment of three new members to its Board of Directors: Ameet Mallik, CEO; Shannon Thyme Klinger, Chief Legal Officer of Moderna; and Mark McCamish, CEO of IconOVir Bio. Chairman Howard Jonas expressed optimism, stating the new board members bring significant expertise to advance the company's oncology pipeline. Ameet Mallik highlighted the importance of their industry experience in maximizing the potential of their therapeutics.