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Regulus Therapeutics Inc. announced the advancement to cohort 4 of the Phase 1b Clinical Trial of RGLS8429 for the treatment of ADPKD. The study will evaluate the safety, efficacy, and impact on total kidney volume in patients with this disease. Positive data from previous cohorts has paved the way for this advancement, with potential for a pivotal Phase 2 trial. The trial aims to assess changes in urinary polycystins, kidney volume, cyst architecture, and overall kidney function.
Regulus Therapeutics Inc. will participate in the Canaccord Genuity Genetic Medicine for Generalists Webcast Series, with CEO Jay Hagan and President Preston Klassen, M.D. The event, hosted by Whitney Ijem on May 1, 2024, at 1:00 p.m. ET, will be live and available for replay on the company's investor relations website for 90 days.