Relief Hldg Stock Price, News & Analysis

Relief Therapeutics Holding SA has announced an extraordinary general meeting (EGM) scheduled for April 28, 2023, in Geneva to vote on a proposed 400-for-1 reverse stock split. This action aims to facilitate a listing of its shares on the Nasdaq Stock Market. The consolidation will not impact the overall market capitalization or shareholders' equity percentages, aside from compensating fractional shares in cash. CEO Jack Weinstein emphasized that this listing would enhance liquidity and access to capital for the company’s development pipeline. Full details of the proposal are available in the EGM invitation and further information can be found on the company's website.

Relief Therapeutics has appointed Guangping Gao, Ph.D., a renowned gene therapy expert, as the chair of its new scientific advisory board (SAB). Dr. Gao's expertise includes the discovery of adeno-associated virus (AAV) serotypes, crucial for gene therapy advancements. His role will focus on providing strategic guidance for the company's genetic medicine initiatives aimed at treating rare diseases. Relief Therapeutics aims to develop potentially curative therapies leveraging Dr. Gao's extensive experience in gene therapy.

Relief Therapeutics announced the presentation of preclinical study results on its PKU GOLIKE product, a prolonged-release amino acid supplement developed with Physiomimic Technology, at the Society for Inherited Metabolic Disorders 44th Annual Meeting in Salt Lake City (March 18-21, 2023). This study shows promising improvements in muscle anabolism and function, critical for patients with Phenylketonuria (PKU), a rare metabolic disorder affecting over 450,000 individuals globally. The findings, indicating enhanced amino acid utilization, will help shape future clinical research. Detailed results will be available on Relief Therapeutics' website after the presentation.

Relief Therapeutics has announced the launch of its new PKU GOLIKE BARs in Europe, designed for patients with phenylketonuria (PKU). These prolonged-release amino acid medical foods come in tropical and red fruit flavors and are made with natural ingredients. Each box contains either 20 bars with 5g protein or 10 bars with 10g protein. The company has eliminated exposure to Credit Suisse and has no funds with closed U.S. banks, mitigating risks from recent banking sector issues. PKU affects over 450,000 patients globally, necessitating strict dietary management to avoid severe health consequences.

Acer Therapeutics reports that preliminary launch activities for OLPRUVA™ are progressing well, with commercial and medical teams being built to support the U.S. launch expected in Q2 2023. The drug is anticipated to be available by early July 2023. Acer has introduced the OLPRUVA™ Navigator service to assist patients and is negotiating access with major payers. The pricing strategy aims for a competitive position, significantly lower than current products like RAVICTI®. Acer will also present a survey on treatment preferences for urea cycle disorders at SIMD 2023.

Relief Therapeutics (OTCQB:RLFTF, OTCQB:RLFTY) announced the U.S. availability of PKU GOLIKE™ bars on Rare Disease Day 2023. These bars are designed for patients with phenylketonuria (PKU), a rare metabolic disorder affecting over 450,000 globally. Developed over four years with input from patients, the bars are available in tropical and red fruit flavors, using Physiomimic™ technology for improved absorption and taste. Each bar contains 5 g or 10 g protein equivalent, meeting dietary needs while limiting phenylalanine intake to under 15 mg per bar. The initiative aims to enhance compliance and address the dietary challenges faced by PKU patients.

Relief Therapeutics has begun enrolling patients in a proof-of-concept study for RLF-TD011, targeting epidermolysis bullosa (EB), a severe skin condition. The study aims to treat up to 17 patients with dystrophic or junctional EB and evaluate the skin microbiome's response to the treatment. RLF-TD011 is a sprayable solution designed for self-administration that aims to reduce infection rates and improve wound healing. The study will last eight weeks, with a follow-up period of four weeks. The potential market for EB treatments is estimated to exceed $1 billion.

Relief Therapeutics has announced a strategic update concerning its financing efforts, opting to withdraw a prior SEC registration statement to explore non-dilutive funding options. This move aims to facilitate a potential listing on the Nasdaq. The company plans a reverse stock split, pending shareholder approval, to enhance its appeal to investors. The proposed reverse split is part of a broader initiative to improve the company's public perception and reduce the number of outstanding shares, which currently stems from past mergers. Relief is focused on treating rare diseases and aims to advance its innovative pipeline, including partnerships for metabolic disorder treatments.