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Repare Therapeutics Inc. Common Shares - $RPTX STOCK NEWS

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Repare Therapeutics Inc. reported financial results for Q1 2024, highlighting clinical progress in various programs. FDA agrees with RP2D for lunresertib plus camonsertib combo. Phase 2 TRESR expansion and Phase 1 LIONS monotherapy trial initiated. $237.0M in cash to fund operations till mid-2026. Camonsertib rights regained, new trial initiations, and board appointment announced. Revenue from collaboration agreements increased to $52.4M. Net income for Q1 2024 was $13.2M.

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Repare Therapeutics and Debiopharm have dosed the first patient in the Phase 1/1b MYTHIC trial, evaluating the combination of PKMYT1 and WEE1 inhibition. This collaboration aims to assess safety, pharmacokinetics, and preliminary clinical activity of lunresertib and Debio 0123, showing promise for cancer patients.

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Repare Therapeutics Inc. (Nasdaq: RPTX) appoints Dr. Steven H. Stein to its Board of Directors, thanking Todd Foley for his contributions. Dr. Stein brings extensive experience in oncology drug development, currently serving as the Chief Medical Officer of Incyte The Company looks forward to his guidance as it advances its precision oncology pipeline.

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Repare Therapeutics Inc. announces participation in upcoming investor conferences to discuss precision oncology. Details include presentations at TD Cowen 44th Annual Healthcare Conference and Bloom Burton 2024 Healthcare Investor Conference.
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Repare Therapeutics Inc. reported financial results for Q4 and full year 2023, highlighting progress in their precision oncology programs. Key achievements include positive data from lunresertib trials, a partnership with Debiopharm, and a milestone payment from Roche. The company also disclosed plans for 2024, including new clinical trials and data readouts. Financially, Repare's cash position is strong, with $223.6 million in cash, cash equivalents, and marketable securities as of December 31, 2023.
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Repare Therapeutics Inc. announces dosing of first patient in Phase 1 LIONS clinical trial for RP-1664, a potential first-in-class PLK4 inhibitor for solid tumors. RP-1664 shows promising tumor growth inhibition in TRIM37-high solid tumors and neuroblastoma models.
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Repare Therapeutics regains control of potential best-in-class oral small molecule ATR inhibitor, camonsertib, following termination of collaboration agreement with Roche. The company will now have full rights to develop and commercialize camonsertib, a promising precision oncology medicine that has shown clinical proof-of-concept in multiple tumor types and genotypes. Repare's deep clinical pipeline includes four wholly-owned synthetic lethal therapies.
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Repare Therapeutics Inc. announced a $40 million milestone payment from Roche upon dosing of the first patient with camonsertib in Roche’s Phase 2 TAPISTRY trial. Repare is eligible to receive up to $1.2 billion in potential milestones, plus royalties on global net product sales. The collaboration also provides Repare with the ability to opt-in to a 50/50 U.S. co-development and profit share arrangement.
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Repare Therapeutics Inc. (RPTX) provides a corporate update and highlights key milestones anticipated in 2024. The company has advanced its pipeline significantly in 2023, presenting strong data from key programs such as lunresertib in combination with camonsertib, and camonsertib in combination with PARP inhibitors. Repare aims to expand its pipeline to four clinical-stage programs by the second half of 2024 and expects to share data readouts from ongoing studies of lunresertib combinations. The company also disclosed its partnership with Debiopharm to explore the potential clinical synergy of Debio 0123, a highly selective clinical WEE1 inhibitor, and lunresertib. Additionally, Repare announced key milestones anticipated in 2024, including the initiation of several Phase 1 studies and the reporting of data from ongoing studies. The company ended 2023 with approximately $223 million in cash, cash equivalents, and marketable securities, which is anticipated to fund planned operations into mid-2026.
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Repare Therapeutics Inc. (RPTX) collaborates with Debiopharm to investigate the combination of lunresertib, a PKMYT1 inhibitor, and Debio 0123, a WEE1 inhibitor, in a new arm of Repare’s ongoing global MYTHIC study. The Phase 1/1b clinical trial is anticipated to initiate in the first half of 2024. The collaboration aims to explore the synergy between the two compounds and share all costs equally. The combination has shown highly synergistic and promising preclinical data, demonstrating potential transformative benefit to patients with high unmet medical need.
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Repare Therapeutics Inc. Common Shares

Nasdaq:RPTX

RPTX Rankings

RPTX Stock Data

160.87M
14.92M
1.02%
94.48%
1.61%
Pharmaceutical Preparation Manufacturing
Manufacturing
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United States of America
SAINT-LAURENT

About RPTX

repare therapeutics is developing new, precision oncology drugs for patients that target specific vulnerabilities of tumor cells. its approach integrates insights from several fields of cell biology including dna repair and synthetic lethality. repare’s platform combines a proprietary, high throughput, crispr‐enabled gene editing target discovery method with high‐resolution protein crystallography, computational biology and clinical informatics. the company is backed by leading global healthcare investors including founding investor versant ventures and mpm capital. for additional information, please visit www.reparerx.com.