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Revolution Medicines, Inc. - $RVMD STOCK NEWS

Welcome to our dedicated page for Revolution Medicines news (Ticker: $RVMD), a resource for investors and traders seeking the latest updates and insights on Revolution Medicines stock.

Revolution Medicines, Inc. (RVMD) is a clinical-stage precision oncology company dedicated to discovering and developing innovative targeted therapies that address the unmet needs of cancer patients. The company leverages its proprietary product engine to target frontier oncology pathways, with a strong focus on the RAS and mTOR signaling pathways, which are crucial for cancer growth and survival. Revolution Medicines’ approach draws inspiration from nature and evolution, harnessing insights from natural products to guide the discovery and development of small molecules that modulate key cancer targets.

The company’s research and development pipeline features several promising candidates, including RMC-4630, a SHP2 inhibitor, and a portfolio of RAS(ON) inhibitors such as RMC-6236, RMC-6291, and RMC-9805. These novel therapies aim to inhibit the active form of RAS proteins, which are common drivers in numerous cancer types. Revolution Medicines is also advancing the SOS1 and 4EBP1/mTORC1 programs, which hold significant potential in combination treatment strategies.

Recent achievements highlight the company’s progress in clinical development. Notably, the RMC-6236 Phase 1/1b trial demonstrated promising clinical activity and a favorable safety profile in patients with advanced solid tumors harboring KRAS mutations. The trial results showed an objective response rate of 38% in non-small cell lung cancer (NSCLC) and 20% in pancreatic ductal adenocarcinoma (PDAC), with disease control rates of 85% and 87%, respectively.

In October 2023, Revolution Medicines announced a pivotal milestone with the merger with EQRx, Inc., enhancing its financial position and enabling further investment in its clinical programs. The merger is expected to add approximately $1.1 billion in net cash proceeds, supporting the advancement of their RAS(ON) and RAS Companion Inhibitors. Dr. Sandra Horning, a renowned oncologist and former Genentech executive, joined the board of directors, bringing invaluable experience to the company.

Revolution Medicines continues to engage the scientific community and stakeholders through presentations at major conferences and investor webcasts. The company remains committed to advancing its robust pipeline of oncology therapies, aiming to revolutionize the treatment landscape for RAS-addicted cancers and improve outcomes for cancer patients worldwide.

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Revolution Medicines, Inc. (RVMD) announced that their CEO will deliver a corporate presentation at the 42nd Annual J.P. Morgan Healthcare Conference on January 9, 2024, to discuss the development of targeted therapies for RAS-addicted cancers.
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Revolution Medicines, Inc. (Nasdaq: RVMD) announced the completion of its acquisition of EQRx, Inc., adding approximately $1.1 billion in net cash to its balance sheet. This move supports the late-stage development of RAS(ON) Inhibitor investigational drugs. Dr. Sandra Horning, a seasoned oncologist and late-stage clinical development leader, has joined Revolution Medicines' Board of Directors.
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RVMD and EQRX Stockholders Approve Acquisition Deal, Expected to Close in November 2023. Revolution Medicines to Issue 55 Million Shares for the Merger.
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Revolution Medicines, a clinical-stage oncology company, presented promising clinical data for RMC-6236 and RMC-6291 at AACR-NCI-EORTC and ESMO Meetings. The company also provided an update on its financial results and announced the expected close of the acquisition of EQRx, Inc. The clinical data showed significant anti-tumor activity for both drugs, supporting their advancement into late-stage development. The acquisition is expected to add approximately $1.1 billion in net cash proceeds. Revolution Medicines aims to revolutionize treatment for RAS-addicted cancers.
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Revolution Medicines, Inc. will report financial results for the third quarter 2023 on November 6, 2023, after market close. The senior management team will host a webcast to discuss the financial results and provide an update on corporate progress. A replay will be available on the company's website for at least 14 days.
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Revolution Medicines announces promising anti-tumor and safety data for RMC-6236 in patients with lung cancer and pancreatic cancer
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Revolution Medicines announces encouraging preliminary clinical data for RMC-6236 and RMC-6291
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Revolution Medicines will present new clinical data for RMC-6236 and RMC-6291 at upcoming oncology conferences. Preliminary safety and pharmacokinetic profiles for RMC-6236 will be presented at the Triple Meeting. Additional antitumor activity data for RMC-6236 will be presented at ESMO. The company will also host an investor webcast to review the clinical data presentations and overall pipeline and strategy.
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Revolution Medicines announces initiation of Phase 1/1b trial for RMC-9805, a KRASG12D(ON) Inhibitor for RAS-addicted cancers.
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Revolution Medicines, Inc. announces the publication of a research paper in Science, describing their tri-complex inhibitor approach to developing small molecules for RAS-addicted cancers. The paper discusses the creation of innovative small molecules that target mutant KRASG12C proteins, which are common causes of lung and colorectal cancers. The compounds showed promising results in preclinical studies, inhibiting oncogenic signaling and driving tumor regressions in human xenograft models. Revolution Medicines is currently evaluating their clinical candidate, RMC-6291, in a Phase 1/1b trial.
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FAQ

What does Revolution Medicines, Inc. specialize in?

Revolution Medicines specializes in developing novel targeted therapies for RAS-addicted cancers by focusing on frontier oncology targets within the RAS and mTOR signaling pathways.

What are some of the key products in Revolution Medicines’ pipeline?

Key products include RMC-4630 (SHP2 inhibitor), RMC-6236, RMC-6291 (KRASG12C), and RMC-9805 (KRASG12D), which are all RAS(ON) inhibitors currently in clinical development.

What recent achievements has Revolution Medicines reported?

Recent achievements include promising clinical trial results for RMC-6236 in advanced solid tumors with KRAS mutations and the completion of a merger with EQRx, Inc. to bolster financial resources.

What is the significance of the RMC-6236 Phase 1/1b trial?

The RMC-6236 trial demonstrated preliminary clinical activity and an acceptable safety profile in patients with NSCLC and PDAC, showing promising objective response and disease control rates.

How does the merger with EQRx benefit Revolution Medicines?

The merger with EQRx is expected to add approximately $1.1 billion in net cash proceeds, supporting the advancement of Revolution Medicines’ clinical pipeline and enhancing its financial position.

Who recently joined the board of Revolution Medicines?

Dr. Sandra Horning, a renowned oncologist and former executive at Genentech, joined the board of directors, bringing significant experience in oncology drug development.

What are RAS(ON) inhibitors?

RAS(ON) inhibitors are designed to inhibit the active form of RAS proteins, which are common drivers in various cancer types, thus potentially offering a new approach in cancer treatment.

How does Revolution Medicines generate insights for its drug discovery?

Revolution Medicines draws inspiration from nature and evolution, particularly focusing on natural products that can inform and guide the discovery of small molecules targeting cancer pathways.

What are some of the ongoing trials at Revolution Medicines?

Ongoing trials include the RMC-6236-001 Phase 1/1b trial for advanced solid tumors with KRAS mutations and the continued development of RAS(ON) inhibitors like RMC-6291 and RMC-9805.

How can investors stay updated on Revolution Medicines’ developments?

Investors can stay updated by attending investor webcasts, accessing the company’s website for news and presentations, and reviewing SEC filings and joint proxy statements.

Revolution Medicines, Inc.

Nasdaq:RVMD

RVMD Rankings

RVMD Stock Data

6.22B
160.83M
2.46%
96.16%
7.29%
Biological Product (except Diagnostic) Manufacturing
Manufacturing
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United States of America
REDWOOD CITY