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Reviva to Present Anti-Inflammatory Impacts of Brilaroxazine in Schizophrenia from the RECOVER 12-month Open Label Extension Trial at Neuroscience 2025

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Reviva Pharmaceuticals (NASDAQ: RVPH) will present new data on the anti-inflammatory effects of brilaroxazine at Neuroscience 2025 in San Diego.

The late-breaker poster (Session A.10, LBP010) on Nov 15, 2025, 1:00–5:00 PM PT covers RECOVER Phase 3 double-blind results in acute schizophrenia and 12-month open-label extension data in clinically stable patients, focusing on BDNF and inflammatory cytokines. Abstracts and poster details are available on the Neuroscience 2025 website.

Reviva Pharmaceuticals (NASDAQ: RVPH) presenterà nuovi dati sugli effetti anti-infiammatori di brilaroxazine a Neuroscience 2025 a San Diego.

Il poster di late-breaker (Sessione A.10, LBP010) il 15 novembre 2025, dalle 13:00 alle 17:00 PT copre i risultati doppio cieco di RECOVER fase 3 in schizofrenia acuta e dati di estensione in aperto di 12 mesi in pazienti clinicamente stabili, concentrandosi su BDNF e citochine infiammatorie. Estratti e dettagli del poster sono disponibili sul sito di Neuroscience 2025.

Reviva Pharmaceuticals (NASDAQ: RVPH) presentará nuevos datos sobre los efectos antiinflamatorios de brilaroxazina en Neuroscience 2025 en San Diego.

El póster de última hora (Sesión A.10, LBP010) el 15 de noviembre de 2025, de 1:00 a 5:00 p.m. PT cubre los resultados dobles ciegos de RECOVER Fase 3 en esquizofrenia aguda y datos de extensión de 12 meses en pacientes clínicamente estables, centrados en BDNF y citocinas inflamatorias. Los resúmenes y detalles del póster están disponibles en el sitio web de Neuroscience 2025.

Reviva Pharmaceuticals (NASDAQ: RVPH)는 샌디에이고에서 열리는 Neuroscience 2025에서 브릴라록시즌(brilaroxazine)의 항염증 효과에 대한 새로운 데이터를 발표할 예정입니다.

late-breaker 포스터(Session A.10, LBP010)는 2025년 11월 15일, 오후 1:00–5:00 PT에 걸쳐 급성 조현병에서 RECOVER 3상 이중맹검 결과와 임상적으로 안정된 환자에서 12개월의 오픈-레이블 확장 데이터를 다루며, BDNF와 염증성 사이토카인에 초점을 맞춥니다. 초록과 포스터 세부정보는 Neuroscience 2025 웹사이트에서 확인할 수 있습니다.

Reviva Pharmaceuticals (NASDAQ: RVPH) présentera de nouvelles données sur les effets anti-inflammatoires de brilaroxazine lors de Neuroscience 2025 à San Diego.

Le poster « late-breaker » (Session A.10, LBP010) le 15 novembre 2025, de 13h00 à 17h00 PT couvre les résultats en double aveugle de RECOVER de la phase 3 chez la schizophrénie aiguë et les données d’extension en open-label sur 12 mois chez des patients clinquement stables, en mettant l’accent sur le BDNF et les cytocines inflammatoires. Les résumés et les détails du poster sont disponibles sur le site Web de Neuroscience 2025.

Reviva Pharmaceuticals (NASDAQ: RVPH) wird neue Daten zu den entzündungshemmenden Wirkungen von brilaroxazin bei Neuroscience 2025 in San Diego vorstellen.

Der Late-Breaker-Poster (Session A.10, LBP010) am 15. November 2025, 13:00–17:00 Uhr PT behandelt die RECOVER-Phase-3-Doppelblind-Ergebnisse bei akuter Schizophrenie und 12-monatige Open-Label-Erweiterungsdaten bei klinisch stabilen Patienten, mit Fokus auf BDNF und entzündliche Zytokine. Abstracts und Poster-Details finden Sie auf der Neuroscience 2025-Website.

Reviva Pharmaceuticals (NASDAQ: RVPH) ستقدم بيانات جديدة حول التأثيرات المضادّة للالتهابات لـ brilaroxazine في Neuroscience 2025 في سان دييغو.

البوستر الهام (جلسة A.10، LBP010) في 15 نوفمبر 2025، من الساعة 1:00 إلى 5:00 مساءً بتوقيت المحيط الهادئ يغطي نتائج RECOVER من المرحلة 3 مزدوجة التعمية في الفصام الحاد وبيانات التمديد مفتوحة القفل لمدة 12 شهراً في المرضى المستقرين سريريًا، مع تركيز على BDNF والسيتوكينات الالتهابية. الملخصات وتفاصيل البوستر متاحة على موقع Neuroscience 2025.

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CUPERTINO, Calif., Nov. 12, 2025 (GLOBE NEWSWIRE) -- Reviva Pharmaceuticals Holdings, Inc. (NASDAQ: RVPH) (“Reviva” or the “Company”), a late-stage pharmaceutical company developing therapies that seek to address unmet medical needs in the areas of central nervous system (CNS), inflammatory and cardiometabolic diseases, today announced that the anti-inflammatory impacts of brilaroxazine from the Phase 3 RECOVER double-blind trial in patients with acute exacerbation of schizophrenia, and from the long-term open-label extension trial in clinically stable schizophrenia patients will be presented as a late-breaker poster presentation at the 2025 Neuroscience meeting taking place November 15–19, 2025 in San Diego, CA.

Details for the poster presentation can be found below:

Title: Brilaroxazine treatment effects on BDNF and inflammatory cytokines in schizophrenia: RECOVER trial in acute and stable patients over 1 year
Session Name: A.10. Schizophrenia
Session Number: LBP010
Date and Time: Saturday, November 15, 2025, 1:00 – 5:00 PM PT

Abstracts and additional details can be found at the 2025 Neuroscience website.

About Reviva 
Reviva is a late-stage biopharmaceutical company that discovers, develops, and seeks to commercialize next-generation therapeutics for diseases representing unmet medical needs and burdens to society, patients, and their families. Reviva’s current pipeline focuses on the central nervous system (CNS), inflammatory and cardiometabolic diseases. Reviva’s pipeline currently includes two drug candidates, brilaroxazine (RP5063) and RP1208. Both are new chemical entities discovered in-house. Reviva has been granted composition of matter patents for both brilaroxazine and RP1208 in the United States, Europe, and several other countries.

Corporate Contact:
Reviva Pharmaceuticals Holdings, Inc.
Laxminarayan Bhat, PhD 
www.revivapharma.com

Investor Relations Contact:
LifeSci Advisors, LLC
PJ Kelleher
pkelleher@lifesciadvisors.com


FAQ

What will Reviva (RVPH) present at Neuroscience 2025 on November 15, 2025?

A late-breaker poster on brilaroxazine effects on BDNF and inflammatory cytokines from RECOVER Phase 3 and 12-month open-label data.

When and where is Reviva's RVPH poster session at Neuroscience 2025?

Session A.10 (LBP010) on Saturday, November 15, 2025, between 1:00–5:00 PM PT in San Diego, CA.

Which trials are included in Reviva's RVPH poster on brilaroxazine?

Data come from the RECOVER Phase 3 double-blind trial in acute exacerbation of schizophrenia and a 12-month open-label extension in stable patients.

What biomarkers does Reviva report for brilaroxazine in the RVPH Neuroscience 2025 poster?

The poster focuses on treatment effects on BDNF and inflammatory cytokines.

Where can investors find the abstract and details for Reviva's RVPH Neuroscience 2025 poster?

Abstracts and poster details are available on the official Neuroscience 2025 website.
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