Recursion Pharmaceuticals, Inc. Stock Price, News & Analysis

MIT and Recursion (RXRX) have jointly developed and released Boltz-2, a groundbreaking open-source AI model for drug discovery. This biomolecular foundation model can predict both molecular structure and binding affinity simultaneously, approaching the accuracy of industry-standard free energy perturbation (FEP) calculations but at speeds up to 1000x faster. Trained on Recursion's NVIDIA supercomputer BioHive-2, Boltz-2 demonstrates superior performance in the CASP16 affinity challenge and utilizes approximately 5 million binding affinity assay measurements. The model features improved affinity prediction, advanced joint modeling capabilities, and enhanced physical plausibility through Boltz-steering. Released under an MIT license for both academic and commercial use, Boltz-2 represents a significant advancement in making large-scale virtual screening more practical and cost-effective for drug development.

Recursion (RXRX), a clinical stage TechBio company, has announced its participation in three major upcoming investor conferences in June 2025. The company will present at the Jefferies Global Healthcare Conference on June 5, the Goldman Sachs 46th Annual Global Healthcare Conference on June 10, and the TDCowen 4th Annual Tools/Dx Revolution Conference on June 23. Interested parties can access the webcasts of these presentations through the events section of Recursion's Investor Relations website at ir.recursion.com.

Recursion (NASDAQ: RXRX), a clinical stage TechBio company, has announced its upcoming participation in two major investor conferences in May 2025. The company will be presenting at the Bank of America 2025 Health Care Conference on Tuesday, May 13, and the JP Morgan Global Technology, Media and Communications Conference on Thursday, May 15. Interested parties can access the webcasts through Recursion's Investor Relations website at ir.recursion.com.

Recursion (RXRX) reported Q1 2025 financial results and business updates, highlighting a strategic portfolio optimization. The company achieved a $7 million milestone payment from Sanofi, bringing total partnership inflows to $130 million. Key clinical developments include REC-4881 showing 43% median reduction in polyp burden in FAP patients. Q1 financials show revenue of $15 million, with a net loss of $203 million. Cash position stands at $509 million, with runway extended to mid-2027. The company streamlined operations post-Exscientia merger, discontinuing 3 clinical programs while maintaining 5+ focused programs in oncology and rare diseases. Expected cash burn for 2025 is ≤$450 million, down from $606 million in 2024. Platform updates include new partnerships with Tempus and HealthVerity, expanding clinical development capabilities.

Recursion (RXRX) announced promising preliminary results from its Phase 1b/2 TUPELO trial of REC-4881, an investigational MEK1/2 inhibitor for Familial Adenomatous Polyposis (FAP). The study showed a median 43% reduction in polyp burden at Week 13 in Phase 2 patients (n=6). Five out of six patients (83%) experienced polyp reductions ranging from 31% to 82%, though one patient showed a 595% increase. The drug demonstrated an acceptable safety profile, with mostly Grade 1-2 adverse events and no Grade ≥4 events reported. FAP, affecting approximately 50,000 individuals across the US and EU5, currently has no FDA-approved treatments. REC-4881 has received Fast Track and Orphan Drug designations from both U.S. FDA and European Commission.

Recursion (RXRX), a clinical stage TechBio company, has scheduled the release of its first quarter 2025 financial results on Monday, May 5, 2025, before market open. The company will host a live (L)earnings call at 8:00 am ET / 6:00 am MT / 1:00 pm GMT on the same day.

The earnings call will be broadcast live across multiple social media platforms, including X (formerly Twitter), LinkedIn, and YouTube. Stakeholders, including investors and analysts, can submit their questions through a dedicated online form.

Recursion (NASDAQ: RXRX) will present preliminary clinical data from its Phase 1b/2 TUPELO trial of REC-4881 for familial adenomatous polyposis (FAP) at Digestive Disease Week 2025. The presentation will take place on May 4, 2025, in San Diego.

Key preliminary findings as of February 7, 2025, show:

• 13 patients received 4 mg of REC-4881 daily
• 84.6% experienced at least one treatment-related adverse event
• Most common side effect was rash/dermatitis acneiform (Grade 1 or 2)
• 5 efficacy-evaluable patients showed >30% median reduction in total polyp burden after 12 weeks

REC-4881, identified through Recursion's AI-powered platform, has received Fast Track and Orphan Drug designations from the FDA and European Commission. FAP affects approximately 50,000 people across the US and major European countries, with no current FDA-approved therapies available.

Recursion (NASDAQ: RXRX) has partnered with HealthVerity to enhance its clinical trial capabilities through real-world data integration. The collaboration will give Recursion access to de-identified data covering over 340M lives in the US, which will be integrated into their Recursion OS platform.

This strategic partnership aims to improve clinical trial design, patient population insights, and trial feasibility assessments. Recursion will leverage HealthVerity's comprehensive healthcare data ecosystem to enhance their AI-driven approach, predict patient responses, and optimize study designs while ensuring regulatory compliance.

The integration of HealthVerity's real-world data into Recursion's platforms is expected to streamline clinical development, reduce costs, and accelerate the development of novel therapeutics while maintaining HIPAA compliance and patient privacy standards.

Recursion (NASDAQ: RXRX) and Enamine have announced a collaboration to create AI-enabled targeted compound libraries for drug discovery. The partnership combines Recursion's AI/ML platform (Recursion OS) with Enamine's REAL Space, the world's largest make-on-demand small molecule collection.

The collaboration has resulted in 10 enriched screening libraries comprising over 15,000 newly synthesized compounds, designed to accelerate drug discovery against 100 key clinical targets in challenging biological areas. By leveraging Recursion's AI technology to predict small molecule compatibility with protein targets, the partnership enables the creation of focused libraries that outperform traditional high-throughput screening collections.

As part of the research collaboration, Recursion gained access to tens of thousands of compounds for its internal discovery needs, while helping develop libraries of broad commercial interest. The curated libraries are now available through Enamine's website for customer hit-finding campaigns.