Welcome to our dedicated page for Sage Therapeutic news (Ticker: SAGE), a resource for investors and traders seeking the latest updates and insights on Sage Therapeutic stock.
Sage Therapeutics, Inc. (former Nasdaq: SAGE) is a Cambridge, Massachusetts-based biopharmaceutical company focused on brain health, with a particular emphasis on postpartum depression. The company reports that it developed the only two FDA-approved treatments indicated for postpartum depression and highlights ZURZUVAE (zuranolone), described as the first-and-only oral treatment for adults with postpartum depression and, in some communications, as a once-daily 14-day oral treatment.
The news flow around Sage has centered on several themes. One major area is commercial updates for ZURZUVAE, including collaboration revenue recognized under its agreement with Biogen, prescription shipment trends for women with postpartum depression, prescriber behavior among obstetrician-gynecologists, and payer coverage metrics. Regular quarterly earnings releases have discussed revenue from ZURZUVAE, other collaboration revenue, research and development spending, selling, general and administrative expenses, restructuring charges, and cash runway expectations.
Another recurring topic is Sage’s research and development pipeline. Company news has described progress with SAGE-319, an extrasynaptic-preferring GABAA receptor positive allosteric modulator being studied for behavioral symptoms associated with certain neurodevelopmental disorders, along with preclinical NMDA receptor negative allosteric modulator programs SAGE-817 and SAGE-039, and evaluation of potential indications for SAGE-324, including seizures in developmental and epileptic encephalopathies.
Corporate and strategic developments are also prominent in Sage’s news. Releases have covered a strategic alternatives review, unsolicited acquisition proposals, and, ultimately, the definitive agreement and subsequent completion of an acquisition by Supernus Pharmaceuticals, Inc. Investors reviewing SAGE-related news can use this page to follow historical earnings announcements, pipeline updates, leadership changes, strategic reviews, and the steps that led to Sage becoming a wholly owned subsidiary of Supernus.
Sage Therapeutics (NASDAQ: SAGE) will participate in a fireside chat at SVB Leerink’s 3rd Annual CNS Forum on June 29th at 4:15pm ET. Investors can access a live webcast on the company's investor page, with a replay available two hours after the event for 30 days. Sage Therapeutics is focused on developing innovative therapies to improve brain health and transform the treatment of debilitating brain disorders. For more information, visit www.sagerx.com.
Sage Therapeutics (Nasdaq: SAGE) announced a live webcast on June 15, 2021, at 8:00 a.m. ET to discuss topline results from the Phase 3 WATERFALL Study of zuranolone for major depressive disorder. This event can be accessed via the investor page on Sage's website. Following the live session, a replay will be available about two hours post-event. Sage Therapeutics focuses on novel therapies aimed at transforming the treatment of debilitating brain disorders, with a commitment to improving brain health.
Sage Therapeutics and Biogen announced that the Phase 3 WATERFALL Study for zuranolone (SAGE-217/BIIB125) in Major Depressive Disorder (MDD) met its primary endpoint. Zuranolone 50 mg showed a significant improvement in depressive symptoms compared to placebo, with a mean change from baseline in HAMD-17 total score at Day 15 of -14.1 versus -12.3 for placebo (p=0.0141). Zuranolone demonstrated a favorable safety profile, with common adverse events being mild to moderate. The U.S. FDA has granted Breakthrough Therapy Designation for zuranolone, indicating its potential as a new treatment option.
Sage Therapeutics (Nasdaq: SAGE) will host the first Sage Science Spotlight webcast on May 20, focusing on SAGE-718, its lead neuropsychiatry product candidate.
The webcast will cover advancements in treating cognitive disorders related to NMDA receptor dysfunction and discuss new data from the PARADIGM Study for patients with mild cognitive impairment due to Parkinson’s disease. Sage will also initiate a Phase 2 study in Huntington’s disease. Expert speakers will include Sage's Chief Research Officer and a leading neurologist.
Access the webcast on Sage's investor page.
Sage Therapeutics reported Q1 2021 results, showcasing advancements in its depression, neurology, and neuropsychiatry franchises. The company highlighted significant clinical data for zuranolone, SAGE-324, and SAGE-718, with ongoing Phase 3 trials anticipated to support potential approvals. Revenue from ZULRESSO reached $1.6 million, a decline from $2.3 million in Q1 2020. R&D expenses decreased to $58.1 million. Despite a net loss of $95.8 million, Sage expects a strong cash position of over $1.7 billion by year-end. The company continues to pursue innovative therapies for brain health disorders.
Sage Therapeutics, a biopharmaceutical company focused on treating brain disorders, will present at two investor conferences in May 2021. The first is the Bank of America Health Care Conference on May 11, 2021, at 10:15 am ET, followed by the RBC Capital Markets Global Healthcare Conference on May 18, 2021, at 8:35 am ET. Live webcasts will be available on the company's investor page, with replays accessible for 30 days. Sage's mission is to develop therapies that improve brain health and transform treatment for depression and neurological disorders.
Sage Therapeutics, Inc. (Nasdaq: SAGE) will host a live webcast on May 4, 2021, at 8:00 a.m. ET to discuss its first quarter 2021 financial results and recent business updates. Investors can access the webcast via the company's investor page. A replay will be available about two hours post-event and archived for 30 days. Sage Therapeutics is dedicated to developing innovative therapies aimed at treating brain disorders, particularly focusing on depression, neurology, and neuropsychiatry.
Sage Therapeutics and Biogen announced positive topline results from the Phase 2 KINETIC Study of SAGE-324 for essential tremor treatment. The study achieved its primary endpoint with a significant reduction in upper limb tremor score, showing a 36% decrease in the SAGE-324 group versus 21% in placebo (P=0.049). Severe tremor patients demonstrated an even greater 41% reduction. Safety profiles were consistent with previous data, and plans for further development of SAGE-324 are underway, reflecting the substantial unmet medical need in treating essential tremor affecting over 6.4 million in the U.S.
Sage Therapeutics (NASDAQ: SAGE) announced its participation in the Stifel 3rd Annual CNS Day fireside chat on March 31, 2021, at 8:00 am ET. This event highlights Sage's commitment to developing innovative therapies for brain disorders. Investors can access a live webcast on the company's investor page, with a replay available two hours post-event and archived for 30 days. Sage Therapeutics focuses on transforming treatment approaches for depression, neurology, and neuropsychiatry, aiming to improve brain health and patient outcomes.
Sage Therapeutics reported 12-month data from the Phase 3 SHORELINE Study evaluating zuranolone for major depressive disorder (MDD). The 30 mg cohort demonstrated favorable safety, with 51% reporting at least one adverse event, consistent with previous studies. 73.5% of patients achieved a clinical response, requiring an average of 2.2 treatments within the year. Interim data from the 50 mg cohort showed 80.5% response rates. Sage aims to provide further data at upcoming conferences, while continuing to assess zuranolone’s long-term efficacy and safety.