Welcome to our dedicated page for Cassava Sciences news (Ticker: SAVA), a resource for investors and traders seeking the latest updates and insights on Cassava Sciences stock.
Cassava Sciences, Inc. (NASDAQ: SAVA) is a clinical-stage biotechnology company based in Austin, Texas that reports extensively on its efforts to develop simufilam, a proprietary, investigational oral small molecule for central nervous system (CNS) disorders. Recent news emphasizes a strategic shift toward tuberous sclerosis complex (TSC)-related epilepsy, following the discontinuation of its Alzheimer’s disease program after two Phase 3 trials did not meet their pre-specified endpoints.
News updates for SAVA commonly cover preclinical and clinical development milestones. Cassava has announced preclinical studies in mouse models of TSC-related epilepsy and focal cortical malformations, reporting that simufilam reduced seizure activity and alleviated neuronal abnormalities. The company also highlights presentations at scientific meetings, such as the TSC International Research Conference, where it shared data on seizure reduction and human safety findings from prior Alzheimer’s Phase 3 studies.
Regulatory and corporate developments are another key theme in Cassava’s news flow. Items include disclosures about the FDA placing the proposed proof-of-concept trial of simufilam in TSC-related epilepsy on full clinical hold pending additional data and protocol changes, as well as updates on the timing implications for clinical trial initiation. Investors also see announcements about leadership appointments in neuroscience and clinical development, board changes, participation in investor conferences, and financial results with commentary on cash resources and expense management.
Litigation and legal matters feature in Cassava’s news as well. The company has reported a binding term sheet to settle a consolidated securities class action for $31.25 million, subject to court approval, and has discussed related loss contingencies in its financial communications. For anyone tracking SAVA, this news page provides ongoing coverage of scientific publications, regulatory interactions, corporate governance changes, and financial and legal updates related to Cassava’s CNS drug development programs.
Cassava Sciences has appointed Premier Research International as its clinical research organization to lead the Phase 3 clinical program for simufilam, aimed at treating Alzheimer's disease. The company plans to initiate this pivotal program in the second half of 2021. With extensive experience in neuroscience, Premier Research will support Cassava in advancing simufilam into critical testing phases. This collaboration marks a significant step forward for Cassava as it seeks to address the pressing need for effective Alzheimer's therapies.
Cassava Sciences, Inc. (Nasdaq: SAVA) announced significant progress in its clinical development of simufilam for Alzheimer's disease. The open-label study successfully enrolled 150 subjects, and results from interim analyses will be presented at the Alzheimer's Association International Conference (AAIC) in July. The Cognition Maintenance Study has commenced with a 30% enrollment rate. Cassava plans to initiate a Phase 3 program in the latter half of 2021, supported by around $282 million in cash. The ongoing research is backed by NIH grants, emphasizing the company's commitment to developing innovative treatments.
Cassava Sciences (Nasdaq: SAVA) announced its participation in the Raymond James 2021 Human Health Innovation Conference. The virtual event is scheduled for June 21-23, 2021.
Management, including President & CEO Remi Barbier and CFO Eric Schoen, will deliver a corporate overview on June 22 at 3:20 PM ET. They will also engage with institutional investors throughout the conference. A replay of the presentation will be accessible until September 20, 2021 on the company's website under the ‘Investors’ tab.
Cassava Sciences, Inc. (Nasdaq: SAVA) announced the appointment of Mr. Richard Barry to its Board of Directors as of June 11, 2021. Mr. Barry, an experienced investor and former managing partner at Eastbourne Capital Management, will provide insights on sustainability and governance. His appointment aims to bolster the company's commitment to societal goals while progressing towards a Phase 3 clinical program for Alzheimer’s disease. Mr. Barry holds 150,000 shares of SAVA, underscoring his confidence in the company’s mission.
Cassava Sciences (Nasdaq: SAVA) is set to join a virtual panel on innovative treatment approaches for Alzheimer’s disease on May 26 at 11:00am Eastern Time. The discussion will be moderated by Jason McCarthy, PhD, from Maxim Group, featuring Remi Barbier, President & CEO of Cassava Sciences. Alzheimer's, affecting approximately 50 million people globally, is a progressive brain disorder without current drug therapies to halt its advancement. The annual global cost of dementia exceeds $1 trillion.
Cassava Sciences has secured a $2.7 million research grant from the National Institutes of Health (NIH) to fund clinical readiness activities for its Phase 3 program with simufilam, a drug candidate targeting Alzheimer's disease. This grant follows a peer review process which validated the clinical and scientific data of simufilam. The company aims to leverage this funding to advance its commitment to developing effective treatments for Alzheimer’s, as the global dementia cost surpasses $1 trillion
Cassava Sciences, a biotechnology company focused on Alzheimer’s disease, has initiated a Cognition Maintenance Study (CMS) to assess the effects of simufilam in patients with the condition. The randomized, controlled study aims to enroll 100 participants and evaluate cognitive changes over six months between those who continue and discontinue treatment. Simufilam targets neurodegeneration and inflammation, and early results have shown positive cognitive outcomes. The study is part of the company’s broader strategy to advance simufilam towards Phase 3 trials.
Cassava Sciences, Inc. (Nasdaq: SAVA) will participate in the B. Riley Securities’ Neuroscience Conference on April 28-29, 2021. Remi Barbier, President & CEO, is set to engage in a virtual Fireside Chat on April 28 at 2:30 PM Eastern. The conference will address topics in neurodegeneration and neuropsychiatry, featuring prominent companies in the field. An archived replay of the chat will be available on Cassava's website for about 90 days post-event. For details, visit CassavaSciences.com.
AUSTIN, Texas, April 26, 2021 (GLOBE NEWSWIRE) -- Cassava Sciences, a clinical-stage biotechnology company focused on Alzheimer’s disease, has been invited to the Sachs 4th Annual Neuroscience Innovation Forum, taking place virtually from April 28-30, 2021. The National Institute on Aging of the NIH will feature Cassava's scientific program during this event. Dr. Lindsay Burns, Senior VP of Neuroscience, will present a 10-minute overview of their Alzheimer’s program. The webcast will be available on Cassava’s website starting April 28 at 8:30 AM ET.
Cassava Sciences (SAVA) reported its Q1 2021 financial results, highlighting a robust cash position of $282.2 million as of March 31, 2021. The company is advancing the pivotal Phase 3 program for simufilam, aimed at treating Alzheimer’s disease, with an expected initiation in the 2nd half of 2021. An interim analysis of a 9-month open-label study will be presented at the Alzheimer’s Association International Conference in July 2021. Initial results indicate improved cognition scores for patients undergoing 6 months of treatment.