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Syndax Pharmaceuticals reports developments as a commercial-stage biopharmaceutical company advancing cancer therapies. Company updates center on Revuforj (revumenib), an FDA-approved menin inhibitor, and Niktimvo (axatilimab-csfr), an FDA-approved monoclonal antibody that blocks the colony stimulating factor 1 receptor.
Recurring news includes quarterly financial results, product revenue for Revuforj and Niktimvo, collaboration revenue from Niktimvo commercialization with Incyte, clinical data presentations in acute leukemia, chronic graft-versus-host disease and related indications, FDA-related product updates, investor conference activity and inducement equity grants under Nasdaq listing rules.
Syndax Pharmaceuticals (Nasdaq:SNDX) granted stock option inducement awards under Nasdaq Listing Rule 5635(c)(4) to four new employees on June 1, 2026. The options cover up to 66,700 shares of common stock under the 2023 Inducement Plan and vest over four years.
Syndax (NASDAQ:SNDX) entered into privately negotiated subscription agreements to issue $250.0 million of 2.25% Convertible Senior Notes due 2031. Closing is expected on June 10, 2026. Net proceeds of about $243 million are earmarked for general corporate purposes, including R&D and commercialization.
The Notes are senior unsecured, bear 2.25% semiannual interest, and are initially convertible at 40.3894 shares per $1,000 principal (conversion price about $24.76, a 35% premium to the June 3, 2026 share price). Syndax can redeem from June 20, 2029, subject to a stock price condition.
Syndax (Nasdaq:SNDX) reported new Revuforj® (revumenib) data from ASCO 2026, including post-transplant and pharmacokinetic results.
In 24 adults and children with high-risk acute leukemia resuming revumenib after HSCT, the 2-year overall survival rate was 90% vs a historical 51%, with low relapse rates and manageable thrombocytopenia. PK data from 335 patients showed flexible dosing with gastric acid reducers, CYP3A4 inhibitors, and varying food conditions.
Syndax Pharmaceuticals (Nasdaq:SNDX) will host an R&D Day on July 14, 2026, at 8:30 AM ET in New York City. Management and key opinion leaders will present updates on late-stage revumenib and axatilimab programs and discuss ongoing trials.
The event will also cover new early-stage assets and plans to leverage company capabilities to bring additional cancer treatment options to patients. A live webcast and limited-time replay will be available in the Investor section of www.syndax.com.
Syndax (Nasdaq:SNDX) announced that four Revuforj (revumenib) abstracts were accepted for presentation at ASCO 2026, including an oral post-transplant maintenance study in 21 adults and children with acute leukemia.
Additional posters cover revumenib pharmacokinetics and designs of two phase 3 trials in newly diagnosed NPM1m or KMT2Ar AML.
Syndax Pharmaceuticals (Nasdaq:SNDX) announced participation in several upcoming investor conferences featuring fireside chats with CEO Michael A. Metzger and the management team.
Events include TD Cowen’s Oncology Innovation Summit, the Jefferies Global Healthcare Conference, and the Goldman Sachs Global Healthcare Conference, with live and replay webcasts via Syndax’s investor website.
Syndax (Nasdaq:SNDX) announced that 12 abstracts featuring Revuforj® (revumenib) were accepted for EHA 2026, covering real‑world, frontline, relapsed/refractory, and post‑transplant acute leukemia settings.
Data span KMT2Ar, NPM1m, and NUP98r leukemias and include trials in progress, reinforcing Syndax’s focus on menin inhibition in AML.
Syndax Pharmaceuticals (Nasdaq: SNDX) granted inducement awards on May 1, 2026, to eight new employees to purchase up to 162,100 shares under its 2023 Inducement Plan. The stock options vest over four years: 25% at one year, then 1/48th monthly over the following 36 months, subject to continued service.
Syndax (Nasdaq: SNDX) reported $64.9M total revenue in 1Q26, including $48.9M Revuforj net revenue and $15.9M Niktimvo collaboration revenue. Cash, cash equivalents and short-term investments were $352.1M. Syndax posted a net loss attributable to common stockholders of $42.7M ($0.48/share). R&D was $58.8M and SG&A was $37.6M. The company expects combined R&D plus SG&A of ~$400M for 2026 (excluding ~$50M non-cash stock comp) and highlighted upcoming data readouts in 2Q26 and topline axatilimab Phase 2 data in 4Q26.
Syndax Pharmaceuticals (Nasdaq: SNDX) will report first quarter 2026 financial results and provide a business update on Thursday, April 30, 2026. Management will host a conference call and live audio webcast at 4:30 p.m. ET.
Access the live audio webcast and slides via the Investors Events & Presentations page or use Conference ID Syndax1Q26 with domestic dial-in 800-590-8290 or international dial-in 240-690-8800. A replay will be posted on the Investors section of the company website approximately 24 hours after the call and will remain available for 90 days.