Baltimore Expands Use of Evolve™ Rodent Birth Control Following Successful Pilot

Rhea-AI Summary

SenesTech (NASDAQ: SNES) announced that Baltimore is expanding its deployment of Evolve™, the company's non-lethal rodent birth control product, following a successful pilot program. The city will implement Evolve™ more broadly in areas that showed measurable improvements during initial testing, integrating it into their existing pest management protocols. Evolve™, an EPA-classified minimum-risk pesticide, works by targeting rodent reproduction through a palatable soft bait that limits fertility in both male and female rodents. The product is designed to complement traditional pest control methods and poses no known risks to people, pets, or the environment when used as directed. Baltimore's pest control personnel reported enhanced results when incorporating Evolve™ into their existing protocols. SenesTech will provide ongoing support, including training and technical assistance throughout the rollout.

Positive

• Successful pilot program leading to expanded deployment in Baltimore
• Integration into existing pest management protocols showing enhanced results
• Product classified as minimum-risk pesticide by EPA, demonstrating safety profile
• Ongoing support contract with Baltimore for training and technical assistance

Negative

• None.

Insights

Environmental Technology Analyst

Baltimore's expansion of SenesTech's rodent birth control solution validates their technology and signals potential revenue growth.

This expansion by Baltimore represents a significant commercial validation for SenesTech's fertility control technology. After completing their pilot program, the city is now implementing Evolve™ more broadly—a strong indicator that the product demonstrated meaningful efficacy during testing. This transition from pilot to expanded deployment suggests the technology delivered on its promised performance metrics in real-world conditions.

The timing is particularly noteworthy as urban centers increasingly seek sustainable pest management alternatives to traditional poisoning approaches. SenesTech's non-lethal fertility control addresses a critical market gap by targeting reproduction rather than simply eliminating existing rodents—a fundamentally more effective approach for long-term population management.

This implementation has several layers of significance for SenesTech's growth trajectory:

• It provides a high-profile reference case in a major metropolitan area
• It establishes a template for municipal adoption that can be replicated
• It demonstrates the complementary role of Evolve™ within existing integrated pest management programs

While the press release doesn't quantify the financial impact, municipal contracts typically involve multi-year commitments and can lead to expanding deployment over time. Baltimore's adoption potentially represents just the initial phase of what could become a substantial recurring revenue stream if performance metrics continue to satisfy city officials.

The EPA's classification of Evolve™ as a minimum-risk pesticide also positions the product favorably amid increasing regulatory scrutiny of traditional rodenticides, creating potential regulatory tailwinds for further adoption in environmentally conscious municipalities.

Full Scale Implementation Expected

SURPRISE, Ariz., June 13, 2025 /PRNewswire/ -- SenesTech, Inc. (NASDAQ: SNES, "SenesTech" or the "Company"), a leader in fertility control solutions for managing animal pest populations, today announced that the City of Baltimore has concluded its initial pilot program and is now transitioning to a broader deployment of Evolve™, one of the Company's non-lethal rodent birth control products.

Following the limited, controlled deployment earlier this year, Baltimore officials have determined that Evolve aligns with the city's integrated pest management (IPM) goals, offering a sustainable method for addressing persistent rodent population challenges. The expanded deployment will focus on areas that experienced measurable improvements during the pilot phase, with additional sites to be added in coordination with local pest management teams.

"We appreciate the City of Baltimore's thoughtful and data-driven approach to rodent management," said Joel Fruendt, President and CEO of SenesTech. "By continuing to incorporate Evolve into their IPM strategy, Baltimore is demonstrating leadership in adopting innovative, humane, and proactive pest control solutions."

Evolve works by targeting the root cause of rodent infestations—reproduction. Designed to be used alongside traditional pest control methods, Evolve is a palatable soft bait that limits fertility in both male and female rodents. Classified as a minimum-risk pesticide by the EPA, it poses no known risk to people, pets, or the environment when used as directed.

The City's decision to proceed with broader implementation follows several months of evaluation, during which Evolve was deployed in key locations as part of an integrated effort to reduce rodent activity. Baltimore's pest control personnel reported enhanced results when Evolve was included in their existing protocols.

"This is an important step forward," added Fruendt. "The commitment by municipalities like Baltimore reflects the growing demand for solutions that go beyond short-term fixes and support long-term urban health and safety."

SenesTech will continue to support the City of Baltimore throughout the rollout, including providing training, deployment guidance, and ongoing technical assistance.

About SenesTech
We are committed to improving the health of the world by humanely managing animal pest populations through our expertise in fertility control. We invented ContraPest^®, the only U.S. EPA-registered contraceptive for male and female rats, as well as Evolve Rat and Evolve Mouse, EPA-designated minimum risk contraceptives for rodents, reflecting our mission to provide products that are proactive, safe and sustainable. ContraPest and Evolve fit seamlessly into all integrated pest management programs, significantly improving the overall goal of effective pest management. We strive for clean cities, efficient businesses and happy households – with a product designed to be humane, effective and sustainable.

For more information visit https://senestech.com/.

Safe Harbor Statement
This press release contains "forward-looking statements" within the meaning of federal securities laws, and we intend that such forward-looking statements be subject to the safe harbor created thereby. Such forward-looking statements include, among others, our belief that by continuing to incorporate Evolve into their IPM strategy, Baltimore is demonstrating leadership in adopting innovative, humane, and proactive pest control solutions; our belief Evolve poses no known risk to people, pets, or the environment when used as directed; our belief that the commitment by municipalities like Baltimore reflects the growing demand for solutions that go beyond short-term fixes and support long-term urban health and safety; and our expectation to continue to support the City of Baltimore throughout the rollout, including providing training, deployment guidance, and ongoing technical assistance. Forward-looking statements may describe future expectations, plans, results or strategies and are often, but not always, made through the use of words such as "believe," "may," "future," "plan," "will," "should," "expect," "anticipate," "eventually," "project," "estimate," "continuing," "intend" and similar words or phrases. You are cautioned that such statements are subject to risks, uncertainties and other factors that could cause actual results to differ materially from those reflected by such forward-looking statements. Such factors include, among others, the successful commercialization of our products, market acceptance of our products, regulatory approval and regulation of our products and other factors and risks identified from time to time in our filings with the Securities and Exchange Commission, including our Annual Report on Form 10-K for the fiscal year ended December 31, 2024. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. Except as required by law, we do not undertake any obligation to publicly update any forward-looking statements, whether as a result of the receipt of new information, the occurrence of future events or otherwise.

Contact Information:
Investors:
Robert Blum, Lytham Partners, LLC
(602) 889-9700
senestech@lythampartners.com

Marketing:
Rochelle Paulet, Director of Marketing, SenesTech, Inc.
(928) 779-4143 x814

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SOURCE SenesTech, Inc.

FAQ

What is SenesTech's Evolve rodent birth control and how does it work?

Evolve is a non-lethal rodent birth control product that works by limiting fertility in both male and female rodents through a palatable soft bait, targeting reproduction as the root cause of infestations.

Is SenesTech's Evolve product safe for humans and pets?

Yes, Evolve is classified as a minimum-risk pesticide by the EPA and poses no known risk to people, pets, or the environment when used as directed.

Why did Baltimore choose to expand SNES's Evolve deployment?

Baltimore expanded Evolve deployment after their pilot program showed measurable improvements in rodent control, with enhanced results when integrated into existing pest management protocols.

What support is SenesTech (SNES) providing to Baltimore for Evolve implementation?

SenesTech is providing training, deployment guidance, and ongoing technical assistance to support Baltimore throughout the Evolve rollout.

How does Evolve integrate with existing pest control methods?

Evolve is designed to be used alongside traditional pest control methods as part of an integrated pest management (IPM) strategy, complementing existing protocols.