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SciSparc Announces Publication of Japanese Patent Application

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SciSparc Ltd. (SPRC) has announced the publication of a Japanese divisional patent application for a novel pharmaceutical combination. The patent covers an innovative combination of paracetamol and palmitoylethanolamide (PEA) designed to enhance pain and fever relief while requiring lower doses than traditional paracetamol treatments.

The combination aims to provide a safer and more effective treatment option by leveraging PEA's ability to boost the body's endocannabinoid system. This synergistic approach could potentially reduce the risk of liver damage associated with paracetamol while improving therapeutic outcomes for acute, chronic, and neuropathic pain, as well as fever management.

SciSparc Ltd. (SPRC) ha annunciato la pubblicazione di una domanda di brevetto divisionale giapponese per una nuova combinazione farmaceutica. Il brevetto riguarda un'innovativa combinazione di paracetamolo e palmitoiletanolamide (PEA) progettata per migliorare il sollievo da dolore e febbre, richiedendo dosi inferiori rispetto ai trattamenti tradizionali a base di paracetamolo.

Questa combinazione mira a offrire un'opzione terapeutica più sicura ed efficace sfruttando la capacità della PEA di potenziare il sistema endocannabinoide del corpo. Questo approccio sinergico potrebbe ridurre il rischio di danni al fegato associati al paracetamolo, migliorando al contempo i risultati terapeutici per il dolore acuto, cronico e neuropatico, oltre alla gestione della febbre.

SciSparc Ltd. (SPRC) ha anunciado la publicación de una solicitud de patente divisional japonesa para una nueva combinación farmacéutica. La patente cubre una innovadora combinación de paracetamol y palmitoiletanolamida (PEA) diseñada para mejorar el alivio del dolor y la fiebre, utilizando dosis más bajas que los tratamientos tradicionales con paracetamol.

La combinación busca ofrecer una opción de tratamiento más segura y efectiva aprovechando la capacidad de la PEA para potenciar el sistema endocannabinoide del cuerpo. Este enfoque sinérgico podría reducir el riesgo de daño hepático asociado con el paracetamol, mejorando los resultados terapéuticos para el dolor agudo, crónico y neuropático, así como para el manejo de la fiebre.

SciSparc Ltd. (SPRC)가 새로운 의약 조합에 대한 일본 분할 특허 출원을 발표했습니다. 이 특허는 파라세타몰과 팔미토일에탄올아마이드(PEA)의 혁신적인 조합을 다루며, 기존 파라세타몰 치료보다 적은 용량으로 통증과 발열 완화를 강화하도록 설계되었습니다.

이 조합은 PEA가 체내 엔도카나비노이드 시스템을 강화하는 능력을 활용하여 더 안전하고 효과적인 치료 옵션을 제공하는 것을 목표로 합니다. 이러한 시너지 효과는 파라세타몰과 관련된 간 손상 위험을 줄이면서 급성, 만성, 신경병성 통증 및 발열 관리에 대한 치료 효과를 향상시킬 수 있습니다.

SciSparc Ltd. (SPRC) a annoncé la publication d'une demande de brevet divisionnaire japonaise pour une nouvelle combinaison pharmaceutique. Le brevet couvre une combinaison innovante de paracétamol et palmitoyléthanolamide (PEA) conçue pour améliorer le soulagement de la douleur et de la fièvre tout en nécessitant des doses plus faibles que les traitements traditionnels au paracétamol.

Cette combinaison vise à offrir une option de traitement plus sûre et plus efficace en exploitant la capacité de la PEA à renforcer le système endocannabinoïde de l'organisme. Cette approche synergique pourrait potentiellement réduire le risque de lésions hépatiques associées au paracétamol tout en améliorant les résultats thérapeutiques pour les douleurs aiguës, chroniques et neuropathiques, ainsi que la gestion de la fièvre.

SciSparc Ltd. (SPRC) hat die Veröffentlichung einer japanischen Teilpatentanmeldung für eine neuartige pharmazeutische Kombination bekannt gegeben. Das Patent umfasst eine innovative Kombination aus Paracetamol und Palmitoylethanolamid (PEA), die darauf ausgelegt ist, Schmerz- und Fiebersymptome zu lindern und dabei geringere Dosierungen als herkömmliche Paracetamol-Behandlungen zu erfordern.

Die Kombination zielt darauf ab, eine sicherere und effektivere Behandlungsoption zu bieten, indem die Fähigkeit von PEA genutzt wird, das körpereigene Endocannabinoid-System zu stärken. Dieser synergetische Ansatz könnte das Risiko von Leberschäden durch Paracetamol verringern und gleichzeitig die therapeutischen Ergebnisse bei akuten, chronischen und neuropathischen Schmerzen sowie bei der Fieberbehandlung verbessern.

Positive
  • Patent application could lead to improved safety profile for pain management treatments
  • Potential for reduced side effects compared to traditional paracetamol treatments
  • Novel drug combination may provide more effective pain and fever relief
  • Technology could address a large global market of pain management patients
Negative
  • Patent is still in application phase, not yet granted
  • Limited to Japanese market at this stage
  • No clinical data or efficacy results presented

TEL AVIV, Israel, May 27, 2025 (GLOBE NEWSWIRE) -- SciSparc Ltd. (Nasdaq: SPRC) ("Company" or "SciSparc"), a specialty clinical-stage pharmaceutical company focusing on the development of therapies to treat disorders and rare diseases of the central nervous system, announced today the publication of a Japanese divisional patent.

The patent application introduces a novel pharmaceutical combination of paracetamol and palmitoylethanolamide (PEA) that may enhance pain relief and fever relief with lower doses and fewer side effects compared to paracetamol monotherapy, with potential for safer and more effective treatment for millions worldwide.

“This patent represents a significant innovation in pain management, that potentially could offer a safer alternative for patients of all ages for using this very common drug,” said Oz Adler, Chief Executive Officer of SciSparc. “This drug candidate combines paracetamol, a widely used pain reliever and fever reducer, with PEA, a natural compound that boosts the body’s endocannabinoid system. By working synergistically, the combination may reduce the required paracetamol dose, minimizing risks like liver damage while improving outcomes for acute, chronic, and neuropathic pain, as well as fever.”

About SciSparc Ltd. (Nasdaq: SPRC):

SciSparc Ltd. is a specialty clinical-stage pharmaceutical company led by an experienced team of senior executives and scientists. SciSparc’s focus is on creating and enhancing a portfolio of technologies and assets based on cannabinoid pharmaceuticals. With this focus, the Company is currently engaged in the following drug development programs based on THC and/or non-psychoactive cannabidiol: SCI-110 for the treatment of Tourette Syndrome, for the treatment of Alzheimer's disease and agitation; and SCI-210 for the treatment of autism and status epilepticus. The Company also owns a controlling interest in a subsidiary whose business focuses on the sale of hemp seeds’ oil-based products on the Amazon.com Marketplace.

Forward-Looking Statements:

This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995 and other Federal securities laws. For example, the Company is using forward looking statements when discussing the potential benefits and advantages of the novel pharmaceutical combination of paracetamol and PEA and that the patent represents a significant innovation in pain management, that potentially could offer a safer alternative for patients of all ages for using this very common drug. Since such statements deal with future events and are based on SciSparc’s current expectations, they are subject to various risks and uncertainties and actual results, performance or achievements of SciSparc could differ materially from those described in or implied by the statements in this press release. The forward-looking statements contained or implied in this press release are subject to other risks and uncertainties, including those discussed under the heading "Risk Factors" in SciSparc's Annual Report on Form 20-F filed with the U.S. Securities and Exchange Commission (the “SEC”) on April 24, 2025, and in subsequent filings with the SEC. Except as otherwise required by law, SciSparc disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events or circumstances or otherwise.

Investor Contact:
IR@scisparc.com
Tel: +972-3-6167055


FAQ

What is the new patent application from SciSparc (SPRC) about?

SciSparc's Japanese patent application covers a novel pharmaceutical combination of paracetamol and palmitoylethanolamide (PEA) designed to enhance pain and fever relief with lower doses and fewer side effects compared to traditional paracetamol treatments.

How does SciSparc's (SPRC) new drug combination work?

The combination works by combining paracetamol with PEA, which boosts the body's endocannabinoid system. This synergistic approach aims to reduce required paracetamol dosage while improving pain relief effectiveness and minimizing side effects.

What are the potential benefits of SciSparc's (SPRC) new pain management patent?

The potential benefits include enhanced pain and fever relief, reduced risk of liver damage due to lower paracetamol doses, fewer side effects, and improved treatment outcomes for acute, chronic, and neuropathic pain.

Where has SciSparc (SPRC) filed the patent for its new pain management drug?

SciSparc has filed a divisional patent application in Japan for its novel paracetamol and PEA combination therapy.
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