Stoke Therapeutics Stock Price, News & Analysis

Stoke Therapeutics reported financial results for Q1 2022, with a net loss of $24.6 million, or $0.66 per share, compared to $16.8 million, or $0.46 per share, in Q1 2021.

The company continues to advance STK-001 in clinical trials for Dravet syndrome, with data readouts expected in 2H 2022. They also announced progress in developing STK-002 for Autosomal Dominant Optic Atrophy (ADOA) and have $293.8 million in cash to fund operations through 2025.

Stoke Therapeutics presented promising preclinical data at the ARVO Annual Meeting, showcasing STK-002 as a potential disease-modifying treatment for Autosomal Dominant Optic Atrophy (ADOA), the most common inherited optic nerve disorder. The data revealed sustained increases in OPA1 protein levels in the retinal tissue of non-human primates following intravitreal administration of STK-002. Significant protein increases were observed even up to eight weeks post-injection, demonstrating the drug's potential to address the underlying cause of ADOA, which affects roughly 1 in 30,000 globally.

Stoke Therapeutics (Nasdaq: STOK) announced new preclinical data supporting the development of STK-002 for treating autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. This proprietary antisense oligonucleotide is designed to increase OPA-1 protein expression to halt or reverse vision loss. The findings will be presented at the ARVO 2022 Annual Meeting in Denver from May 1-4, 2022. Currently, ADOA affects approximately one in 30,000 people globally, with no approved treatment available.

Stoke Therapeutics, Inc. (Nasdaq: STOK), a biotechnology company focused on RNA-based medicines, will present at the 21st Annual Needham Virtual Healthcare Conference on April 12, 2022, at 8:00 a.m. ET. The presentation will be in a fireside chat format, available via live webcast on Stoke's website. Stoke aims to address severe diseases by upregulating protein expression using its proprietary TANGO approach. Their lead compound, STK-001, is in clinical testing for Dravet syndrome, while STK-002 targets autosomal dominant optic atrophy.

Stoke Therapeutics, Inc. (Nasdaq: STOK) reported a net loss of $85.8 million for 2021, reflecting an increase in research and development expenses to $54.2 million. The company continues to advance its clinical pipeline, including ongoing Phase 1/2a studies for STK-001 in treating Dravet syndrome and preclinical studies for STK-002 targeting Autosomal Dominant Optic Atrophy (ADOA). With $220.4 million in cash and a recent $60 million collaboration with Acadia Pharmaceuticals, Stoke is positioned to fund operations through mid-2024 and share additional clinical data in 2H 2022.

Stoke Therapeutics, Inc. (Nasdaq: STOK), a biotechnology firm focused on RNA-based therapies for severe diseases, will present at the Cowen 42nd Annual Health Care Conference on March 7, 2022, at 9:10 a.m. ET. The event will be accessible via a live webcast on their official website, with a replay available for 30 days. Stoke utilizes its innovative TANGO approach to develop targeted treatments, such as STK-001 for Dravet syndrome and STK-002 for autosomal dominant optic atrophy. The company is headquartered in Bedford, Massachusetts.

Ceptur Therapeutics, a biotechnology company focused on U1 Adaptor technology, has successfully completed a $75M Series A financing round. The round was co-led by venBio Partners and Qiming Venture Partners USA, with participation from various investors including Bristol Myers Squibb and Janus Henderson Investors. The funds will be used to advance their genetic medicine pipeline. Ceptur's U1 Adaptors aim to regulate gene expression at the pre-mRNA level, offering innovative therapeutic applications for genetic diseases.

Acadia Pharmaceuticals and Stoke Therapeutics have formed a collaboration to co-develop RNA-based therapies for severe neurodevelopmental diseases, including SYNGAP1 syndrome and Rett syndrome. Acadia gains exclusive licenses for two additional preclinical programs. Stoke receives a $60 million upfront payment, with potential milestone payments reaching $907 million, along with royalties. The partnership combines Stoke’s TANGO research platform with Acadia’s development expertise, aiming to enhance treatment options for patients with these debilitating conditions.

Stoke Therapeutics, Inc. (NASDAQ: STOK) announced its participation in the 40th Annual J.P. Morgan Healthcare Conference on January 10, 2022, at 4:30 p.m. ET. The conference will feature a live audio webcast available on the company's investor relations website, along with a replay accessible for 30 days post-event. Stoke focuses on developing RNA-based medicines to address severe diseases by upregulating protein expression, with its lead compound STK-001 currently in clinical testing for Dravet syndrome.