Welcome to our dedicated page for Shattuck Labs news (Ticker: STTK), a resource for investors and traders seeking the latest updates and insights on Shattuck Labs stock.
Shattuck Labs, Inc. (STTK) is a clinical-stage biotechnology company developing innovative dual-function fusion proteins targeting cancer and autoimmune diseases. This page serves as the definitive source for official company announcements, research milestones, and financial updates.
Investors and industry professionals will find timely updates on STTK's clinical trials, regulatory developments, and strategic partnerships. The curated news collection includes press releases on pipeline advancements, collaborations with pharmaceutical leaders, and progress across its proprietary ARC® platform programs.
Key content categories include updates on lead candidates like SL-172154, financial reporting disclosures, and scientific presentations. All materials are sourced directly from company communications to ensure accuracy and compliance.
Bookmark this page for streamlined access to STTK's latest developments in bi-functional therapeutics. Check regularly for critical updates impacting the company's position in immuno-oncology and autoimmune treatment innovation.
Shattuck Labs (NASDAQ: STTK), a biotechnology company focused on developing novel therapeutics targeting TNF superfamily receptors for inflammatory and immune-related diseases, has announced its participation in the upcoming 24th Annual Needham Virtual Healthcare Conference.
The company's CEO, Taylor Schreiber, M.D., Ph.D., will deliver a presentation on April 9, 2025, at 3:00 PM EDT and participate in one-on-one meetings during the conference, which runs from April 7-10, 2025. A live webcast of the presentation will be accessible through the company's website, with a replay available for up to 30 days afterward.
Shattuck Labs (NASDAQ: STTK) reported its Q4 and full-year 2024 financial results, highlighting the advancement of SL-325, a potential first-in-class DR3 blocking antibody for inflammatory bowel diseases (IBD). The company presented favorable preclinical data at ECCO 2025, demonstrating safety and full receptor occupancy.
Key financial metrics include:
- Cash position of $73.0 million as of December 31, 2024
- Q4 2024 net loss of $18.7 million ($0.37 per share)
- Full-year 2024 net loss of $75.4 million ($1.49 per share)
- R&D expenses decreased to $67.2 million in 2024 from $74.3 million in 2023
The company terminated its SL-172154 program and is now focused on SL-325, with an IND filing expected in Q3 2025. Current cash runway is expected to fund operations into 2027.
Shattuck Labs (NASDAQ: STTK) announced positive preclinical data from an IND-enabling GLP toxicology study of SL-325, their DR3 blocking antibody for inflammatory bowel disease (IBD) treatment. The study, presented at the 20th Congress of ECCO, demonstrated that SL-325 was well-tolerated in non-human primates with no evidence of toxicity or residual agonism.
The study evaluated safety, pharmacokinetics, pharmacodynamics, and immunogenicity over a 4-week dosing period followed by a 4-week recovery period. Three doses (1, 10, and 100 mg/kg) were administered intravenously, showing full and durable DR3 receptor occupancy at all dose levels. No adverse effects, infusion-related reactions, or organ dysfunction were observed, even at the highest dose of 100 mg/kg.
The company expects to file an IND in Q3 2025, with projected human dosing at 1 mg/kg Q2W through Q4W maintenance and 3 mg/kg Q2W through Q8W maintenance.
Shattuck Labs (NASDAQ: STTK) announced an upcoming oral presentation at the 20th Congress of ECCO in Inflammatory Bowel Diseases 2025, taking place in Berlin from February 19-22, 2025. The presentation will showcase results from IND-enabling toxicology studies of SL-325, their first-in-class DR3 blocking antibody, conducted in non-human primates.
Dr. Taylor Schreiber, CEO of Shattuck, will deliver the digital oral presentation titled 'Pre-Clinical Development of SL-325, a High Affinity DR3 Blocking Antibody, for Durable Blockade of the DR3/TL1A Axis in Inflammatory Bowel Disease' on February 20, 2025, at 6:15 PM CET. The presentation materials will be made available on the company's website after the event.
Shattuck Labs (NASDAQ: STTK) has announced an upcoming poster presentation at the 2025 Crohn's and Colitis Congress in San Francisco, California, scheduled for February 6-8, 2025. The presentation will focus on SL-325, a DR3-targeted, antagonistic antibody developed for the treatment of IBD.
The poster will be presented by Dr. Suresh de Silva, Shattuck's Co-Chief Scientific Officer, on Friday, February 7, 2025, from 5:00 PM to 6:30 PM PST at the Congress Exhibit Hall in The Moscone Center. The presentation materials will be made available on the company's website in the Events and Presentations section after the event.
Shattuck Labs (NASDAQ: STTK), a biotechnology company focused on developing therapeutics targeting TNF superfamily receptors for inflammatory and immune-related diseases, announced its participation in the 43rd Annual J.P. Morgan Healthcare Conference. The event will take place in San Francisco from January 13-16, 2025.
Dr. Taylor Schreiber, CEO of Shattuck, will deliver a corporate update presentation on January 16, 2025, at 7:30 a.m. PT at The Westin St. Francis in the Elizabethan B room. The presentation will be available via live webcast on the company's website, with a replay accessible for up to 30 days afterward.
Shattuck Labs (NASDAQ: STTK) provided a corporate update highlighting key milestones for 2025, focusing on their DR3 blocking antibody program, SL-325. The company plans to present preclinical data at upcoming scientific conferences and expects several significant developments, including:
- GLP toxicology study data readout in Q1 2025
- IND filing in Q3 2025
- Phase 1 clinical trial initiation in Q3 2025
- DR3 bispecific development candidate nomination in H2 2025
The company reports a strong financial position with $90.1 million in cash, cash equivalents, and investments as of September 30, 2024, which is expected to fund operations into 2027. Management expressed optimism about SL-325's potential to achieve complete blockade of the DR3/TL1A signaling pathway based on non-human primate studies.
Shattuck Labs (NASDAQ: STTK), a biotechnology company developing novel therapeutics targeting TNF superfamily receptors for cancer and chronic immune-related diseases treatment, announced its participation in two upcoming investor conferences. The company's CEO, Dr. Taylor Schreiber, will present at the Piper Sandler 36th Annual Healthcare Conference on December 3, 2024, at 12:30 p.m. ET, and participate in a fireside chat at the Evercore 7th Annual HealthCONx Conference on December 4, 2024, at 8:45 a.m. ET. Live webcasts will be available on the company's website with replays archived for up to 90 days.
Shattuck Labs (NASDAQ: STTK) reported Q3 2024 financial results and announced a strategic shift to focus on SL-325, a first-in-class DR3 blocking antibody. The company ended Q3 with $90.1 million in cash and investments, compared to $101.1 million year-over-year. Q3 net loss was $16.7 million ($0.33 per share), improved from $27.5 million ($0.65 per share) in Q3 2023. R&D expenses decreased to $16.3 million from $24.2 million, while G&A expenses reduced to $4.6 million from $5.1 million. The company completed restructuring plans and expects current cash to fund operations into 2027, beyond SL-325's Phase 1 trial results.
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