Springworks Therapeutics, Inc. Stock Price, News & Analysis

SpringWorks Therapeutics, Inc. (Nasdaq: SWTX) has announced an exclusive licensing agreement with KU Leuven and VIB for novel small molecule inhibitors targeting the TEA Domain (TEAD) family, aimed at treating biomarker-defined solid tumors linked to the Hippo pathway. An upfront payment of $11 million will be made, along with potential future milestones totaling $285 million. The company plans to nominate a development candidate in 2022 and commence IND-enabling studies. This strategic advancement is expected to enhance SpringWorks' portfolio of targeted therapies for cancer patients.

SpringWorks Therapeutics (Nasdaq: SWTX) announced the initiation of a Phase 1b clinical trial for nirogacestat, a novel gamma secretase inhibitor, combined with teclistamab, an investigational bispecific antibody. This trial targets patients with relapsed or refractory multiple myeloma, aiming to evaluate safety and efficacy. Nirogacestat has shown promise in preclinical studies by enhancing the effectiveness of BCMA-targeted therapies. The trial is part of a collaboration with Janssen Research, which covers trial costs, excluding nirogacestat supply. SpringWorks also continues its Phase 3 study for nirogacestat as a standalone treatment for desmoid tumors.

SpringWorks Therapeutics (SWTX) announced the appointment of Bhavesh Ashar as Chief Commercial Officer, effective immediately. With over 20 years of experience in oncology, Ashar previously held senior roles at Bayer and Sanofi Genzyme. His leadership is expected to enhance commercial operations as the company advances its targeted oncology portfolio, including two registrational trials for nirogacestat and mirdametinib. The company aims to report data from these trials later this year, signaling potential growth in addressing severe rare diseases and cancers.

SpringWorks Therapeutics (SWTX) reported strong fourth quarter and full-year financial results for 2020, with a revenue of $35.0 million driven by a $35 million upfront payment from Jazz Pharmaceuticals. The company ended the year with $561.8 million in cash and marketable securities. Notably, interim data from the Phase 2b ReNeu trial of mirdametinib showed that 50% of the first 20 adult patients achieved an objective response. SpringWorks anticipates multiple data readouts in 2021, including topline data from the Phase 3 DeFi trial.

SpringWorks Therapeutics has reported interim results from the Phase 2b ReNeu trial of mirdametinib for NF1-associated plexiform neurofibromas (NF1-PN). As of January 22, 2021, 50% of enrolled patients achieved an objective response, with 80% remaining on study. The trial is nearing 70% enrollment, expected to complete in the second half of 2021, indicating robust interest in mirdametinib, which has shown a favorable safety profile with mostly mild adverse events. A conference call to discuss these results is set for today at 8:30 AM ET.

SpringWorks Therapeutics (SWTX), a clinical-stage biopharmaceutical firm, announced participation in three upcoming investor conferences. The events include the Cowen 41st Annual Health Care Conference on March 3, the H.C. Wainwright Global Life Sciences Conference on March 9, and the Barclays Global Healthcare Conference on March 10. Webcasts of these presentations will be available on the company's website afterward. SpringWorks focuses on developing treatments for rare diseases and cancers, emphasizing its precision medicine approach and two late-stage clinical trials.

SpringWorks Therapeutics, a clinical-stage biopharmaceutical company (Nasdaq: SWTX), will have its CEO, Saqib Islam, participate in a fireside chat at the Guggenheim Healthcare Talks 2021 Oncology Day on February 12, 2021, at 3:00 p.m. EST. The live webcast can be accessed on their Investors & Media section. SpringWorks focuses on developing precision medicine for patients with rare diseases and cancer, advancing clinical trials for targeted oncology products. For more details, visit their website.

SpringWorks Therapeutics, Inc. (Nasdaq: SWTX) announced that CEO Saqib Islam will present at the 39th Annual J.P. Morgan Healthcare Conference on January 12, 2021, at 7:30 a.m. EST. The presentation will focus on the company’s commitment to developing life-changing medicines for patients with rare diseases and cancer. Investors can access the live webcast on the company’s website, with a replay available afterward. SpringWorks is at the forefront of clinical development, advancing targeted oncology products and strategic partnerships in the biopharmaceutical industry.

SpringWorks Therapeutics (Nasdaq: SWTX) has announced the promotions of Badreddin Edris to Chief Operating Officer and L. Mary Smith to Chief Development Officer. Edris has been pivotal in advancing the company's strategy for nirogacestat and has extensive background in biotechnology. Smith, a founding member, has successfully led clinical programs and regulatory strategies. CEO Saqib Islam praised their leadership, highlighting the importance of their roles in advancing clinical development programs for rare diseases and cancer.