Welcome to our dedicated page for Protara Therapeutics news (Ticker: TARA), a resource for investors and traders seeking the latest updates and insights on Protara Therapeutics stock.
Protara Therapeutics, Inc. (Nasdaq: TARA) is a clinical-stage biotechnology company developing therapies for cancer and rare diseases, and its news flow reflects progress across its investigational programs. Company announcements frequently highlight updates on TARA-002, an investigational cell-based therapy in development for non-muscle invasive bladder cancer (NMIBC) and lymphatic malformations (LMs), as well as on IV Choline Chloride, an investigational phospholipid substrate replacement therapy for patients on long-term parenteral support.
Investors following TARA news can expect detailed coverage of clinical trial milestones, including interim data from the Phase 2 ADVANCED-2 trial in NMIBC and the Phase 2 STARBORN-1 trial in pediatric LMs. Recent press releases have discussed complete response rates, safety and tolerability findings, and regulatory feedback from the U.S. Food and Drug Administration (FDA) on potential registrational paths for TARA-002 in both BCG-unresponsive and BCG-naïve NMIBC populations.
News items also report on regulatory designations and programs, such as Breakthrough Therapy, Fast Track, and Rare Pediatric Disease designations for TARA-002 in LMs, and Fast Track and Orphan Drug Designations for IV Choline Chloride in patients on long-term parenteral nutrition. In addition, Protara’s releases describe participation of TARA-002 in the FDA’s Chemistry, Manufacturing, and Controls Development and Readiness Pilot (CDRP) Program.
Another key theme in TARA news is capital markets activity, including underwritten public offerings of common stock under the company’s shelf registration statement on Form S-3, with proceeds directed toward the clinical development of TARA-002 and other programs. Corporate updates may reference conference presentations, such as appearances at healthcare conferences, and scheduled webcasts to review new clinical data.
By monitoring this news page, readers can follow Protara’s disclosed clinical data updates, regulatory interactions, financing events, and other material developments that the company reports through press releases and related communications.
Protara Therapeutics, Inc. (Nasdaq: TARA) announced the grant of inducement non-qualified stock options totaling 41,500 shares to two new employees. The options have an exercise price of $22.45, which reflects the company's closing trading price on December 1, 2020, the grant date. Vested shares will occur over four years, with an initial 25% vesting on the one-year anniversary of each employee's start date, followed by monthly vesting. This award was approved by the Compensation Committee in accordance with NASDAQ Listing Rule 5635(c)(4).
Protara Therapeutics, Inc. (Nasdaq: TARA) has announced participation in two upcoming virtual investor conferences in December 2020. The events include the Piper Sandler 32nd Annual Virtual Healthcare Conference and the Evercore ISI 3rd Annual HealthCONx Virtual Conference, where Protara will present on December 3, 2020, at 12:10 PM ET. A live webcast of the Evercore presentation will be available on the company's website, and a replay of the Piper fireside chat is currently accessible. Protara is focused on transformative therapies for cancer and rare diseases.
Protara Therapeutics (TARA) reported third-quarter 2020 results, highlighting a strong cash position of $166M as of September 30, and a net loss of $8M, compared to $2.4M in Q3 2019. The company confirmed initial comparability between TARA-002 and OK-432, with plans to complete GMP batch runs by mid-2021. Protara is set to initiate a Phase 1 trial for TARA-002 in non-muscle invasive bladder cancer in 2021 and has requested an FDA meeting to discuss the regulatory path for TARA-002 in lymphatic malformations. R&D expenses surged to $2.8M, with general and administrative costs reaching $5.3M.
Protara Therapeutics, Inc. (Nasdaq: TARA) announced that CEO Jesse Shefferman will present at the Jefferies Virtual London Healthcare Conference on November 18, 2020, at 1:45 PM ET. A webcast of the presentation will be available on the Company’s website and archived for 90 days. Protara focuses on developing transformative therapies for cancer and rare diseases, including TARA-002 for non-muscle invasive bladder cancer and IV Choline Chloride for intestinal failure-associated liver disease. For more details, visit www.protaratx.com.
Protara Therapeutics (Nasdaq: TARA) has issued inducement non-qualified stock options for 5,200 shares to two new employees. The exercise price is set at $17.84, the closing price on November 2, 2020. Vesting occurs over four years, with 25% vesting after one year and the remainder monthly over 36 months, contingent upon continued employment. This grant complies with NASDAQ Listing Rule 5635(c)(4). Protara focuses on innovative therapies for cancer and rare diseases, including TARA-002 for bladder cancer and IV Choline Chloride for liver disease.
Protara Therapeutics (Nasdaq: TARA) announced the pricing of two underwritten public offerings, totaling 4,600,000 shares of common stock at $16.87 each and 4,148 shares of non-voting Series 1 Convertible Preferred Stock priced at $16,873.54 each, expected to close on September 24, 2020. The company anticipates receiving $147.6 million in gross proceeds, primarily for development activities associated with its lead therapy, TARA-002, targeting non-muscle invasive bladder cancer and lymphatic malformations. The offerings are conducted under an effective shelf registration statement.
Protara Therapeutics (Nasdaq: TARA) announced advancements in the clinical development of its lead therapy, TARA-002, for non-muscle invasive bladder cancer (NMIBC) and lymphatic malformations. Following constructive discussions with the FDA, initial comparability between TARA-002 and OK-432 has been confirmed, with further GMP runs planned for mid-2021. A Phase 1 study for NMIBC is set for 2021, with Phase 2 anticipated in 2022. The company will also seek a meeting with the FDA regarding TARA-002’s BLA for lymphatic malformations, supported by positive historical data from OK-432.
Protara Therapeutics (Nasdaq: TARA) announced the granting of 27,500 inducement stock options to two new employees, priced at $20.51 per share, the closing price on September 1, 2020. The options will vest over four years, with 25% vesting after one year and the remainder vesting monthly thereafter. This approval aligns with NASDAQ Listing Rule 5635(c)(4). Protara focuses on developing treatments for rare diseases, including its lead program TARA-002 for lymphatic malformations and IV Choline Chloride for IFALD.
Protara Therapeutics (Nasdaq: TARA) announced FDA's Rare Pediatric Disease designation for TARA-002, aimed at treating Lymphatic Malformations (LMs), which are rare congenital conditions. TARA-002 is a cell-based therapy utilizing the immunopotentiator OK-432, already approved in Japan and Taiwan. A Phase 2 trial showed promising results, with 86% of pediatric patients displaying significant response. This designation highlights the urgent medical need for LMs treatment, and Protara is poised to explore further development steps with the FDA.
Protara Therapeutics (TARA) announced the appointment of Barry P. Flannelly, Pharm.D, to its Board of Directors, replacing Scott Braunstein, M.D. Dr. Flannelly brings over 20 years of experience in the pharmaceutical and biotech sectors, currently serving as Executive Vice President at Incyte. CEO Jesse Shefferman expressed optimism about leveraging Dr. Flannelly's expertise to advance Protara's lead program, TARA-002, aimed at treating lymphatic malformations. The transition occurs at a pivotal time for Protara as it seeks to enhance its drug development pipeline.