Theravance Bioph Stock Price, News & Analysis

Theravance Biopharma (NASDAQ: TBPH) will report its third quarter 2021 financial results on November 3, 2021, after market close. A conference call will follow at 5:00 PM ET. The call can be accessed by dialing (855) 296-9648 domestically or (920) 663-6266 internationally, using confirmation code 9772385. Company highlights include its focus on respiratory medicines and notable products like YUPELRI for COPD. Future financial benefits may arise from agreements with GSK related to certain programs.

Theravance Biopharma (NASDAQ: TBPH) announced significant strategic actions aimed at enhancing shareholder value, including a 75% workforce reduction, affecting around 270 positions, with expected completion by February 2022. The company anticipates annualized operating expense savings of approximately $165 million in 2022. Updated financial guidance projects R&D expenses to drop from $195-225 million in 2021 to $55-65 million in 2022, while SG&A expenses are expected to reduce to $30-40 million. The firm plans to focus on its respiratory therapeutic portfolio, notably YUPELRI and TRELEGY, aiming for positive cash flow in the second half of 2022.

Theravance Biopharma (NASDAQ: TBPH) announced that its Phase 3 study of ampreloxetine for treating symptomatic neurogenic orthostatic hypotension (nOH) did not meet the primary endpoint. While mild to moderate adverse events were reported, no serious side effects were attributed to the drug. The company plans to analyze the findings further and present results at a future scientific forum. CEO Rick E Winningham expressed disappointment, highlighting the unmet need for effective treatments for nOH.

Theravance Biopharma (NASDAQ: TBPH) announced disappointing top-line results from its Phase 2b induction study of izencitinib for ulcerative colitis. The study failed to meet its primary endpoint of change in total Mayo score and the secondary endpoint of clinical remission at week 8 compared to placebo. However, izencitinib was well-tolerated, showing similar adverse event rates to placebo. The company plans to further analyze the study data and upcoming results from ongoing studies, including a Crohn's Phase 2 study expected in early 2022.

Theravance Biopharma reported its Q2 2021 financial results, highlighting a total revenue of $12.9 million, a decrease of $2.1 million year-over-year. Revenue from YUPELRI collaboration with Viatris was $10.9 million, translating to a 35% share of net sales. R&D expenses reduced to $51.1 million, while SG&A expenses rose to $25.9 million. The company closed a public offering raising $115.6 million and anticipates key clinical results for its products in upcoming quarters. Cash position remains strong at $265 million.

Theravance Biopharma (NASDAQ: TBPH) will report its Q2 2021 financial results and provide a business update on August 3, 2021, after market close. A conference call will follow at 5:00 p.m. ET. The company focuses on organ-selective medicines for inflammation and immunology, aiming to enhance therapeutic effectiveness while minimizing side effects. They leverage expertise in developing lung-selective medicines, including FDA-approved YUPELRI for COPD. For more details, visit www.theravance.com.

Theravance Biopharma (NASDAQ: TBPH) has announced the pricing of its public offering of 6.7 million ordinary shares at $15.00 per share, aiming to raise approximately $100.5 million. The offering is set to close on June 29, 2021, subject to customary closing conditions. Additionally, underwriters have a 30-day option to purchase up to 1,005,000 additional shares. The offering is led by SVB Leerink and Evercore ISI. Theravance Biopharma has filed the necessary registration with the SEC and will publish a final prospectus supplement shortly.

Theravance Biopharma (NASDAQ: TBPH) announced a proposed public offering of its ordinary shares, which includes a 30-day underwriters' option for an additional 15% of shares. The offering is contingent upon market conditions. Proceeds will primarily fund the development of ampreloxetine for neurogenic orthostatic hypotension and izencitinib for ulcerative colitis and Crohn's disease. Remaining funds will support other clinical initiatives and working capital. The offering is subject to customary closing conditions, and no assurance can be given regarding its completion.

Theravance Biopharma (NASDAQ: TBPH) announced top-line results from its Phase 2 study of 3 mg once-daily nezulcitinib for hospitalized COVID-19 patients. Despite not meeting the primary endpoint, the trial showed a favorable trend in 28-day all-cause mortality (6 deaths in nezulcitinib group vs. 13 in placebo, HR: 0.42, p=0.08). The trial involved 210 patients and demonstrated good tolerability with lower adverse events compared to the placebo. The company plans to consult with regulatory agencies on further study protocols.