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TScan Therapeutics, Inc. reports clinical and corporate developments for its T cell receptor-engineered T cell therapy pipeline. The company’s cancer programs include TSC-101 in the ALLOHA heme trial for patients with hematologic malignancies undergoing allogeneic hematopoietic cell transplantation, and CD45-targeted candidates TSC-102-A01 and TSC-102-A03 with cleared IND applications.
Recurring TCRX updates cover clinical data presentations, trial enrollment and manufacturing-process updates, FDA interactions, financial results, healthcare conference participation, and portfolio priorities. The company also describes early work in in vivo engineering for solid tumors and target discovery in T cell-mediated autoimmune disorders.
TScan Therapeutics (TCRX) announced significant advancements in its liquid tumor candidates TSC-100 and TSC-101 at the ASH Annual Meeting. These T-cell receptor therapies aim to address hematologic malignancies and prevent relapse post-hematopoietic cell transplant. The company plans to file investigational new drug applications for both therapies by the end of 2021. A Phase 1 clinical trial is expected to commence in H1 2021. TScan will host a virtual KOL event on December 15, 2021, to discuss the posters and clinical trial design.
TScan Therapeutics (Nasdaq: TCRX) announced a virtual event on December 15, 2021, featuring Dr. Yi-Bin Chen from MGH and Harvard Medical School. The session will focus on key insights from the company’s two poster presentations on lead T-cell receptor engineered therapies, TSC-100 and TSC-101, at the 63rd American Society of Hematology Annual Meeting. Attendees will gain insights into hematopoietic cell transplant and relapse prevention strategies. A live Q&A will follow the presentations, which will be archived on the company’s website.
TScan Therapeutics has completed the construction of a GMP manufacturing facility in Waltham, Massachusetts, aiming to support upcoming clinical milestones, including multiple IND filings for its TCR-engineered therapies TSC-100 and TSC-101 for liquid tumors. The 7,000 square-foot facility is operational and will provide early-stage production capacity. Additionally, TScan signed a ten-year lease for an extra 115,000 square feet to accommodate future growth. The company is expected to treat its first patient in the first half of 2022.
TScan Therapeutics, a biopharmaceutical company specializing in T-cell receptor engineered therapies for cancer, will participate in two upcoming investor conferences. These include the Jefferies London Healthcare Conference on November 18, 2021, and the Evercore ISI 4th Annual HealthCONx Conference on December 2, 2021. Webcasts of each fireside chat will be accessible for on-demand listening on the company’s website. TScan's lead therapies, TSC-100 and TSC-101, target hematologic malignancies and aim to prevent leukemia relapse.
TScan Therapeutics (TCRX) reported third-quarter 2021 financial results, highlighting progress in its TCR-T therapy pipeline. The company expects to file IND applications for lead liquid tumor therapies TSC-100 and TSC-101 by year-end. The newly launched TSC-204 solid tumor program targets MAGE-A1 and aims for IND submission in 2022. Financially, TScan recorded a net loss of $15.8 million, with cash reserves of $182.3 million projected to sustain operations into 2024. R&D expenses rose to $14.2 million from $5.8 million year-over-year.
TScan Therapeutics (Nasdaq: TCRX) announced two abstracts for its TCR-engineered therapies, TSC-100 and TSC-101, accepted for presentation at the ASH Annual Meeting from December 11-14, 2021. Targeted at preventing relapse post-hematopoietic cell transplant (HCT) in myeloid leukemia, these therapies focus on minor histocompatibility antigens HA-1 and HA-2. TScan plans to submit investigational new drug applications by year-end 2021. The company aims to begin a Phase 1/2 trial in Q1 2022, exploring safety and efficacy, with about 40% of patients potentially qualifying for these treatments.
TScan Therapeutics (Nasdaq: TCRX) has appointed Heather Savelle as Vice President of Investor Relations, bringing over 20 years of experience in corporate communications and investor relations, especially within the life sciences sector. David Southwell, CEO, emphasized the importance of her expertise as TScan approaches significant development milestones. Ms. Savelle expressed excitement in advancing the company's mission and plans to support the pipeline for TCR-T therapies TSC-100 and TSC-101, targeting FDA submissions in Q4 2021.
TScan Therapeutics, focusing on T-cell receptor therapies for cancer, will have CEO David Southwell join a virtual fireside chat at the Chardan 5th Annual Genetic Medicines Conference on October 5, 2021, at 2:00 p.m. ET. The chat will be accessible via live webcast on the company's website, with an archived replay available afterward. TScan is developing innovative treatments, including TSC-100 and TSC-101, targeting hematologic malignancies and various solid tumors.
TScan Therapeutics, Inc. (Nasdaq: TCRX) has appointed Zoran Zdraveski, J.D., Ph.D., as Chief Legal Officer. With over 20 years of experience in corporate law and business operations in the biopharmaceutical sector, Zdraveski is expected to significantly contribute to TScan’s efforts in advancing their T-cell receptor engineered therapies for cancer treatment. His expertise includes building intellectual property portfolios, which is crucial as TScan develops therapies targeting novel cancer antigens.
WALTHAM, Mass., Sept. 02, 2021 – TScan Therapeutics (Nasdaq: TCRX) announced that its CEO, David Southwell, will participate in a virtual fireside chat at the Morgan Stanley 19th Annual Global Healthcare Conference on September 10, 2021, at 4:15 p.m. ET. A live webcast of the event will be accessible on the company’s website, with an archived replay available post-event.
TScan Therapeutics focuses on developing T-cell receptor engineered therapies for cancer treatment, including TSC-100 and TSC-101 for hematologic malignancies.