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Trevi Therapeutics to Participate in Upcoming March Events

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Trevi Therapeutics, Inc. (TRVI) announces senior management's participation in upcoming healthcare conferences in March 2024 to discuss the investigational therapy Haduvio™ for chronic cough in IPF and RCC. Events include TD Cowen 44th Annual Health Care Conference, Connecticut Rare Disease Forum, Leerink Partners Global Biopharma Conference, and BIO-Europe Spring.
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NEW HAVEN, Conn., Feb. 28, 2024 /PRNewswire/ -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for patients with chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC), today announced that senior management will attend and participate in the following events in March.

TD Cowen 44th Annual Health Care Conference
March 4-6, 2024, Boston, MA
Corporate Presentation: Tuesday, March 5 at 2:50 PM ET
Presenter: Jennifer Good, President and CEO

A live webcast of the TD Cowen corporate presentation will be accessible from the 'Investors & News' section on the Company's website at www.TreviTherapeutics.com. An archived replay of the webcast will also be available for 30 days on the Company's website following the event.

Connecticut Rare Disease Forum
March 7, 2024, JAX Genomic Medicine, Farmington, CT
Panel Discussion: Research & Innovation, Treatments from 1:30 – 4:30 PM ET
Trevi Panelist: Jennifer Good, President and CEO
Register here to attend.

Leerink Partners Global Biopharma Conference
March 11-13, 2024, Miami Beach, FL

BIO-Europe Spring
March 18-20, 2024, Barcelona, Spain

About Trevi Therapeutics, Inc.
Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for patients with chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC). Trevi also is evaluating Haduvio for prurigo nodularis. Haduvio is a dual ĸ-opioid receptor agonist and µ-opioid receptor antagonist that works both centrally in the brain as well as peripherally in the lungs and has the potential for a synergistic antitussive effect to treat chronic cough.

The impact of chronic cough is significant and often leads to a decline in patients' social, physical, and psychological quality of life. In IPF, chronic cough may lead to worsening disease and may be associated with a higher risk of progression, death, or need for lung transplant. There are no approved therapies for the treatment of chronic cough in IPF and current treatment options provide minimal relief to patients. RCC affects up to 10% of the adult population, and Haduvio's expansion into RCC has the potential to reach patients suffering from moderate to severe chronic cough. There are also no approved therapies for RCC in the US.

Parenteral nalbuphine is not scheduled by the U.S. Drug Enforcement Agency. Trevi intends to propose Haduvio as the trade name for oral nalbuphine ER. Its safety and efficacy have not been evaluated by any regulatory authority.

For more information, visit www.TreviTherapeutics.com and follow Trevi on X (formerly Twitter) and LinkedIn.

Investor Contact
Katie McManus
Trevi Therapeutics, Inc.
203-304-2499
k.mcmanus@trevitherapeutics.com

Media Contact
Rosalia Scampoli
914-815-1465
rscampoli@marketcompr.com

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/trevi-therapeutics-to-participate-in-upcoming-march-events-302073494.html

SOURCE Trevi Therapeutics, Inc.

Trevi Therapeutics is developing Haduvio™ (oral nalbuphine ER) for patients with chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC).

The TD Cowen 44th Annual Health Care Conference will be held on March 4-6, 2024, in Boston, MA.

Jennifer Good, President and CEO of Trevi Therapeutics, will be presenting at the TD Cowen corporate presentation on Tuesday, March 5 at 2:50 PM ET.

The live webcast of the TD Cowen corporate presentation can be accessed from the 'Investors & News' section on Trevi Therapeutics' website at www.TreviTherapeutics.com.

The panel discussion at the Connecticut Rare Disease Forum will focus on Research & Innovation, Treatments.

The BIO-Europe Spring conference will be held on March 18-20, 2024, in Barcelona, Spain.
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About TRVI

trevi therapeutics, inc. is a late-stage biopharmaceutical company focused on developing nalbuphine® er for chronic pruritic conditions. pruritus develops in various dermatologic, metabolic, hematologic and neuropathic conditions. the company is pursuing several pruritic conditions for clinical development, including its lead indication of prurigo nodularis. prurigo nodularis is a chronic pruritic dermatologic condition characterized by the presence of pruriginous lesions (excoriative/ulcerative papules and nodules) on the skin. there are no approved therapies in the us or eu for this condition. nalbuphine® er is an oral extended release synthetic opioid with a dual mechanism of action, mu receptor antagonist and kappa receptor agonist, both of which have been shown in research to be effective in abolishing itch. because of nalbuphine® er’s unique dual mechanism of action, which has shown efficacy in addressing pruritus in human clinical trials, the company believes nalbuphine® er can