Welcome to our dedicated page for 2Seventy Bio news (Ticker: TSVT), a resource for investors and traders seeking the latest updates and insights on 2Seventy Bio stock.
2seventy bio, Inc. (Nasdaq: TSVT) is an immuno-oncology cell therapy company centered on Abecma (idecabtagene vicleucel; ide-cel), a BCMA-directed autologous CAR T cell therapy for adult patients with relapsed or refractory multiple myeloma after at least two prior lines of therapy. The TSVT news stream features company announcements that combine scientific, commercial, and corporate developments related to this program and its broader collaboration with Bristol Myers Squibb (BMS).
Investors and observers following TSVT news will find regular updates on Abecma’s U.S. commercial performance, including quarterly and full-year revenues as reported by BMS, trends in demand such as patients undergoing apheresis, and commentary on Abecma’s role in the multiple myeloma treatment landscape. Releases also discuss regulatory milestones, label expansions into earlier-line settings, and decisions around clinical studies such as the discontinuation of enrollment in the Phase 3 KarMMa-9 trial in newly diagnosed multiple myeloma.
Corporate and financial news for 2seventy bio includes quarterly earnings reports, changes in operating expenses, net cash spend, and cash, cash equivalents, and marketable securities. The company has reported transactions such as the sale of its oncology R&D business to Regeneron and the sale of its Hemophilia A program and gene editing technology to Novo Nordisk, which it characterizes as supporting an exclusive focus on Abecma. Conference participation and investor events, including healthcare conferences and fireside chats, are also covered in TSVT news items.
A key current theme in 2seventy bio’s news is its definitive merger agreement with Bristol Myers Squibb. News releases describe the agreed all-cash acquisition, the tender offer structure, the Hart-Scott-Rodino review process, and the expectation that, following completion of the transaction and a second-step merger, 2seventy bio’s common stock will no longer trade on Nasdaq. For readers tracking TSVT, the news page provides an evolving record of Abecma’s commercial trajectory, strategic partnerships, and the company’s pending transition into BMS.
2seventy bio reported first-quarter 2022 results, achieving $56 million in U.S. commercial revenue from ABECMA. The company remains on track to meet its revenue guidance of $250-$300 million for the year. The firm ended the quarter with $452.5 million in cash, projecting a runway into 2025. Key milestones include the enrollment of first patients in vital clinical studies for SC-DARIC33 and bbT369, with potential advancements in treatment for AML and B-NHL. The company reported a net loss of $85.7 million, reflecting ongoing investments in its operations.
2seventy bio (NASDAQ: TSVT) announced promising preclinical data for bbT369, a novel CAR T cell therapy targeting CD79a and CD20, showing enhanced efficacy against B cell non-Hodgkin lymphoma (B-NHL). bbT369 aims to address limitations of existing CAR T therapies by overcoming known mechanisms of treatment failure. Currently, the CRC-403 Phase 1/2 study is enrolling patients to assess its safety and efficacy, with initial results expected in 2022. This innovative approach could offer new hope for patients with relapsed or refractory B-NHL.
2seventy bio (Nasdaq: TSVT) will present at the CG Horizons in Oncology Virtual Conference on April 14, 2022, at 1:30 PM ET. The focus will be on new approaches to attacking AML. Live webcasts of the presentations will be accessible in the Investors and Media section of the company's website, with replays available for 30 days afterward. 2seventy bio aims to revolutionize cancer therapies through innovative cell treatments, emphasizing speed and efficacy in research and development.
2seventy bio (Nasdaq: TSVT) closed a $170 million private placement and reported 2021 financial results, with ABECMA generating $158 million in U.S. revenue. The company anticipates 2022 U.S. ABECMA revenues of $250-$300 million, tracking towards the high end due to strong patient demand. Cost reduction measures decreased net cash spend guidance to $190-$220 million for 2022, extending cash runway into 2025.
Positive developments include increased ABECMA manufacturing capacity planned for 2022, and key management appointments to drive growth.
2seventy bio, Inc. (NASDAQ: TSVT) has announced a private placement sale of approximately 13.9 million shares at $12.20 per share, raising around
2seventy bio, Inc. (NASDAQ: TSVT) announced key leadership appointments, welcoming
2seventy bio (NASDAQ: TSVT) announced its participation in two upcoming investor conferences. The first is the SVB Leerink 10th Annual Global Healthcare Conference on
2seventy bio provided a strong outlook for 2022, predicting
2seventy bio has entered an option and license agreement with Novo Nordisk for developing an in vivo gene editing treatment for hemophilia A, leveraging its megaTAL™ technology. The agreement includes an upfront payment of
2seventy bio (NASDAQ: TSVT) announced new clinical data from its oncology cell therapy portfolio at the American Society of Hematology Annual Meeting. Key highlights include updates from the Phase 1 CRB-402 study of bb21217 for multiple myeloma and analyses from the pivotal KarMMa study of ABECMA, the first CAR T cell therapy for this condition. Patients treated with ABECMA showed improved quality of life and durable responses, with 69% overall response rates and a 23.8-month median duration of response. Preclinical data for SC-DARIC33 were also presented, indicating its potential to treat pediatric AML.
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