Welcome to our dedicated page for Twist Bioscience news (Ticker: TWST), a resource for investors and traders seeking the latest updates and insights on Twist Bioscience stock.
Twist Bioscience Corporation (NASDAQ: TWST) is a synthetic biology and biotechnology company whose news flow reflects its focus on synthetic DNA tools, silicon-based DNA synthesis and research-enabling technologies. Company announcements frequently describe Twist as a mid-cap growth and value biotech company serving customers in medicine, agriculture, industrial chemicals and defense, where its DNA-based products support research and development programs.
On this page, readers can follow TWST news related to product launches, collaborations, financial updates and corporate developments. Recent press releases have highlighted the launch of research-grade plasmid DNA preps for nucleic acid therapeutics research, including animal origin-free and transfection-grade options with specific quality attributes and target yields. Other announcements cover expanded collaborations, such as the Trinity Freestyle Fast Hybridization workflow developed with Element Biosciences for the AVITI sequencing platforms.
Investors and researchers can also track earnings-related news, including preliminary revenue updates, quarterly and full-year financial results, and associated conference calls and webcasts. Corporate governance and compensation updates, such as inducement equity grants under Nasdaq Listing Rule 5635(c)(4), appear in Twist’s news stream as well.
In addition, Twist publishes news on biosecurity and policy engagement, including participation in a Science paper examining biosecurity screening practices in AI-assisted protein design. Conference presentations at major healthcare and life science events are also regularly announced. For anyone following TWST stock or the evolution of synthetic DNA technologies, this news page provides a centralized view of Twist Bioscience’s public communications and key milestones.
Twist Bioscience (Nasdaq: TWST) and bitBiome have announced a strategic collaboration, launching a joint Transaminase Enzyme Screening Kit. This kit contains 48 diverse transaminase enzymes for in-house screening and evaluation. The collaboration combines Twist's high-capacity DNA synthesis technology with bitBiome's proprietary database of over two billion microbe sequences.
The kit aims to provide labs and pharmaceutical companies with improved enzymes for biocatalysis, particularly for synthesizing active pharmaceutical ingredients (APIs). Transaminases are important in creating chiral amines, valuable building blocks for the pharmaceutical industry, offering a potential 'green alternative' to conventional synthesis methods.
This partnership leverages bitBiome's diverse sequence database and Twist's large-scale DNA synthesis capabilities to create innovative solutions for the biomanufacturing industry.
Twist Bioscience (NASDAQ: TWST) reported strong fiscal Q3 2024 results, with record revenue of $81.5 million, up 28% year-over-year. The company saw significant improvements in gross margin, reaching 43.3%, a 900 basis point increase from the previous year. Twist raised its FY 2024 revenue guidance to $310-$311 million and expects gross margin to be at the high end of the range at approximately 42%.
Key highlights include:
- SynBio revenue grew to $33.0 million
- NGS revenue increased to $43.4 million
- Biopharma revenue reached $5.1 million
- Shipped products to approximately 2,300 customers
- Launched new products including Multiplexed Gene Fragments and Express Antibodies
Despite the strong revenue growth, Twist reported a net loss of $85.6 million for the quarter, including a $45 million impairment related to Biopharma assets.
Twist Bioscience (NASDAQ: TWST) announced the first patient dosing in Pure Biologics' exploratory Phase 0 clinical study of PBA-0405, a fully human IgG1 antibody discovered using Twist's synthetic antibody phage display libraries. The study aims to evaluate the pharmacodynamic activity of PBA-0405 in solid tumors, including head and neck squamous cell carcinoma, certain soft-tissue sarcomas, and triple-negative breast cancer.
PBA-0405 targets ROR1, a tumor-associated antigen, and is designed to make tumors visible to the immune system and induce an immune response. This marks the first antibody identified using Twist Biopharma Solutions' Library of Libraries to be tested in patients, validating the potential of their synthetic antibody libraries for discovering novel drug candidates for hard-to-treat cancers.
Twist Bioscience (NASDAQ: TWST) announced it will release its fiscal 2024 third quarter financial results on Friday, August 2, 2024, before market opening. The company will host a conference call and live audio webcast at 8:00 a.m. ET to discuss the results and provide business updates. The press release with financial results will be accessible on Twist Bioscience's website under the Investor Relations section. Interested participants can register on the company's website to receive the necessary dial-in information for the call. A webcast replay will be available for two weeks.
Twist Bioscience (NASDAQ: TWST) has expanded its high-throughput antibody portfolio with the launch of the CHO Express Antibodies, complementing their existing HEK293 antibodies. This expansion aims to support biopharma companies by providing customizable, cost-effective, and scalable antibody production solutions. CHO cell lines are pivotal in biotherapeutic drug manufacturing, and Twist's new service can deliver sequence-perfect IgG antibodies in as few as 13 business days. The antibodies range from 15 μg to 3,000 μg and include detailed yield data for screening. This development improves the efficiency and reduces the costs associated with antibody discovery and production.
Twist Bioscience (NASDAQ: TWST) has introduced a synthetic RNA control for H5N1 Influenza A, a key contributor to Highly Pathogenic Avian Influenza (HPAI). The new control covers 99.9% of the hemagglutinin (HA) and neuraminidase (NA) genome regions, facilitating enhanced research without the need for live viruses.
CEO Emily M. Leproust highlighted the importance of providing innovative tools for global monitoring and vaccine development. The synthetic control allows work to be undertaken in BSL-1 labs, speeding up research while maintaining high biosecurity standards.
This launch is part of Twist's broader portfolio of synthetic viral controls and research tools, aimed at supporting next-generation sequencing (NGS) and polymerase chain reaction (PCR) assays. The company also offers products for other viral and respiratory diseases, including a comprehensive viral research panel for detecting H5N1 in wastewater.
Twist Bioscience (NASDAQ: TWST) has announced the discovery of TB206-001, a first-in-class antibody targeting the adenosine A2A receptor (A2AR), which could enhance cancer immunotherapy. The preclinical study, published in PLOS ONE, shows that TB206-001 has high affinity and tumor-suppressing activity, especially in colon tumor-bearing HuCD34-NCG mice, outperforming PD-1 inhibitors. The antibody targets GPCRs, common in immune cells and certain cancers, and works by blocking A2AR, thereby activating immune cells. Twist Bioscience is offering TB206-001 for out-licensing, indicating its potential for further clinical development.
Twist Bioscience (NASDAQ: TWST) announced its participation in the U.S. AI Safety Institute Consortium (AISIC), a group formed by the Department of Commerce’s National Institute of Standards and Technology (NIST). As part of the consortium, Twist Bioscience aims to advance the development and deployment of safe and trustworthy AI. The company emphasizes its commitment to biosecurity, leveraging its high-quality synthetic DNA and silicon platform to support the creation of interoperable safety standards. The consortium comprises over 200 member companies, including industry leaders, academia, government entities, and civil society organizations, all dedicated to ensuring the responsible growth of AI technologies.
Twist Bioscience (NASDAQ: TWST), a biotechnology company specializing in synthetic DNA, has announced its executives' participation in several upcoming investor conferences. Patrick Finn, Ph.D., president and COO, will join a fireside chat at the Leerink Partners Healthcare Crossroads Conference on May 29 in Austin, TX. Emily Leproust, Ph.D., CEO and co-founder, will present at the William Blair Growth Stock Conference on June 4 in Chicago, IL, at the Jefferies Global Healthcare Conference on June 6 in New York, NY, and will participate in a fireside chat at the Goldman Sachs 45th Annual Global Healthcare Conference on June 11 in Miami, FL. The sessions will be webcast live and available on the company's website, with replays accessible for 30 days after the events.
Twist Bioscience (TWST) has launched Twist Multiplexed Gene Fragments (MGFs), pools of directly synthesized double-stranded DNA up to 500 base pairs in length, with no limit on sequence number, enabling high-throughput screening applications. This offering allows for rapid screening of diverse targets for CRISPR and genome engineering, antibody discovery, protein engineering, and more. The customizable fragments have a quick turnaround time, starting at 8 business days, making them versatile for various applications.