Welcome to our dedicated page for Vir Biotechnology news (Ticker: VIR), a resource for investors and traders seeking the latest updates and insights on Vir Biotechnology stock.
Vir Biotechnology, Inc. (Nasdaq: VIR) is a clinical-stage biopharmaceutical company developing immune-based medicines for serious infectious diseases and cancer, and its news flow reflects active clinical and corporate development. Company announcements highlight progress in chronic hepatitis delta (CHD), where Vir Biotechnology is advancing a combination of tobevibart, an investigational broadly neutralizing monoclonal antibody targeting hepatitis B surface antigen, and elebsiran, an investigational hepatitis B virus-targeting siRNA, through the ECLIPSE registrational program.
News updates frequently cover clinical data readouts and milestones, such as Phase 2 SOLSTICE trial results in CHD showing rates of undetectable hepatitis delta virus RNA and safety findings for the tobevibart and elebsiran combination. Additional releases describe enrollment status and timelines for the ECLIPSE 1, 2 and 3 trials, which are designed to provide efficacy and safety data for potential regulatory submissions and to support access and reimbursement in key markets.
Vir Biotechnology also issues news on its oncology portfolio of PRO-XTEN dual-masked T-cell engagers, including VIR-5500 in metastatic castration-resistant prostate cancer, VIR-5818 in HER2-expressing tumors and VIR-5525 in EGFR-expressing solid tumors. These updates may include first-patient-dosed announcements, Phase 1 dose escalation progress, and plans to present safety and efficacy data at scientific meetings.
Corporate and financial communications, such as quarterly results, conference presentations and licensing agreements, also feature prominently. For example, the company has reported on a license agreement with Norgine for CHD commercial rights in Europe, Australia and New Zealand and has provided guidance on its cash runway. Investors and followers of VIR news can use this page to monitor clinical milestones, regulatory-related updates, partnering activity and financial disclosures as the company advances its infectious disease and oncology programs.
Vir Biotechnology is advancing its collaboration with GlaxoSmithKline to evaluate VIR-7832, a monoclonal antibody aimed at treating COVID-19. The Phase 1b/2a clinical trial, which starts in Q1 2021, will assess VIR-7832's ability to clear infected cells and enhance T cell function. This trial will be conducted through the AGILE initiative across multiple UK sites. This study builds on the first antibody, VIR-7831, which is already in Phase 3 trials, highlighting a robust pipeline focused on addressing the pandemic.
Vir Biotechnology announced the initiation of a Phase 1 clinical trial for VIR-1111, an investigational HIV T cell vaccine, in late December 2020. This trial is a result of a decade-long collaboration with Oregon Health & Science University and the Bill & Melinda Gates Foundation. The trial aims to assess the safety and immunogenicity of VIR-1111, which is designed to elicit a strong immune response by generating CD4 and CD8 T cells to attack HIV-infected cells. The study involves healthy adults previously infected with human cytomegalovirus.
Vir Biotechnology, a clinical-stage immunology company, announced that CEO George Scangos, Ph.D., will present virtually at the 39th Annual J.P. Morgan Healthcare Conference on January 12th at 11:00 am PT/2:00 pm ET. The presentation will be accessible through a live webcast on the Vir website and will be archived for 30 days. Vir focuses on treating and preventing infectious diseases through innovative immunology technologies, with a pipeline targeting SARS-CoV-2, hepatitis B, influenza A, HIV, and tuberculosis.
Vir Biotechnology and GlaxoSmithKline announced the initiation of a Phase 3 clinical trial for VIR-7831, an investigational monoclonal antibody aimed at treating hospitalized adults with COVID-19. The trial, part of the NIH’s ACTIV program, will assess safety and efficacy against standard care. A total of 300 participants will receive either VIR-7831 or a placebo, with follow-ups for clinical status. This therapy has shown potential in neutralizing SARS-CoV-2, which could contribute significantly to treatment options as cases surge globally.
Vir Biotechnology announced the appointment of Jeffrey Hatfield to its Board of Directors. Hatfield brings over 30 years of experience in the pharmaceutical industry, having previously led Vitae Pharmaceuticals and held executive positions at Bristol Myers Squibb. His expertise in commercial programs and platform-based companies is expected to drive Vir's growth, especially as the company tackles serious infectious diseases, including COVID-19. Hatfield's past successes, including the $640 million acquisition of Vitae by Allergan, position him as a valuable asset for Vir's future endeavors.
Vir Biotechnology reported third-quarter financial results for the period ending September 30, 2020, with total revenues increasing to $1.9 million from $1.4 million year-over-year, driven by research activities under HIV and TB grants. However, research and development expenses surged to $70.7 million, leading to a net loss of $84.6 million, or $0.67 per share, compared to a loss of $48.3 million, or $4.60 per share, in Q3 2019. The company is advancing its SARS-CoV-2 programs, including the Phase 3 trial of VIR-7831, expecting initial results in January 2021.
Vir Biotechnology has published a comprehensive study on the SARS-CoV-2 receptor binding motif (RBM), revealing high mutation rates that enhance immune evasion. Notably, the N439K variant has shown resistance to several monoclonal antibodies, indicating ongoing challenges in vaccine development. Analyzing over 130,000 viral sequences, the research emphasizes the necessity for continuous monitoring of emerging variants. The findings suggest that VIR-7831 aims to target conserved epitopes to mitigate resistance, enhancing long-term immunity against COVID-19.
Vir Biotechnology, Inc. (Nasdaq: VIR) will announce its third-quarter financial results for the period ended September 30, 2020, on November 10, 2020. The corporate update will be released after market close and made available on their website. Vir focuses on treating serious infectious diseases using innovative immunology technologies. Their development pipeline includes candidates for various diseases such as hepatitis B, influenza A, SARS-CoV-2, HIV, and tuberculosis.
Vir Biotechnology has released data on VIR-2482, a monoclonal antibody aimed at preventing influenza A. The preclinical and Phase 1 studies reveal promising results, including broad neutralizing capability against historical strains and a prolonged half-life that supports potential once-per-season dosing. Notably, elderly patients with comorbidities are at high risk for severe influenza complications, with hospitalization rates between 19%-44% and associated costs of $4,122-$8,181 per patient. This underscores the need for effective prevention strategies, which VIR-2482 may fulfill.
Vir Biotechnology and Alnylam Pharmaceuticals will participate in a virtual fireside chat at the H.C. Wainwright Hepatitis B Virus Mini-Conference on October 20, 2020, at 9:30 am PT/12:30 pm ET. Phil Pang, M.D., Chief Medical Officer of Vir, and Vasant Jadhav, Ph.D., Vice President of Research at Alnylam, will lead the discussion. The event will be accessible via live webcast on both companies' investor websites, with archives available for 30 days post-event.
Vir focuses on treating serious infectious diseases, while Alnylam specializes in RNA interference therapeutics.