Vtv Therapeutics Stock Price, News & Analysis

vTv Therapeutics Inc. (Nasdaq: VTVT) announced the appointment of Rich Nelson as Acting CEO following the resignation of Deepa Prasad. Nelson, a board member since 2020, brings extensive experience in corporate development and mergers. Prasad will remain as a Strategic Advisor for six months. The company is focused on advancing its lead drug, TTP399, which received FDA Breakthrough Therapy Designation after showing a 40% reduction in hypoglycemic episodes in its Phase 2 study. vTv aims to launch pivotal trials for TTP399 in 2022.

vTv Therapeutics (Nasdaq: VTVT) has updated its corporate presentation on TTP399, a novel treatment aimed at reducing hypoglycemic episodes in diabetes patients. The drug may act as an oral adjunctive therapy in the $16B insulin market. Nearly 600 patients have been tested with no diabetic ketoacidosis reported. vTv holds worldwide rights for TTP399 and plans global pivotal trials in 2022 while seeking non-dilutive capital through licensing outside North America and Europe. Additionally, the company explores licensing for HPP737 and other assets.

vTv Therapeutics Inc. (Nasdaq: VTVT) announced a 65% workforce reduction to prioritize its lead program, TTP399, for type 1 diabetes, as it prepares for Phase 3 pivotal trials. TTP399 demonstrated a ~40% reduction in hypoglycemic episodes compared to placebo in Phase 2 studies and has received Breakthrough Therapy Designation from the FDA. The company also suspended development on HPP737, a psoriasis treatment, while supporting partnered programs. vTv aims to focus on improving the quality of life for diabetes patients with TTP399.

vTv Therapeutics Inc. (Nasdaq: VTVT) reported third-quarter 2021 financial results, highlighting a cash position of $19.6 million, up from $10.8 million in Q2 2021. The company generated $3.0 million in revenue, largely from milestones achieved with partners. Net loss attributable to shareholders was $1.09 million, or $(0.02) per share, compared to $(0.01) in Q2 2021. The firm is refocusing on TTP399 for type 1 diabetes, having received FDA Breakthrough Therapy Designation. Upcoming pivotal studies for TTP399 are planned for H1 2022, with cost reduction measures being evaluated.

vTv Therapeutics Inc. (Nasdaq: VTVT) announces the appointment of Deepa Prasad as President and CEO, effective immediately, following the retirement of Stephen L. Holcombe. Under her leadership, the company plans to launch phase 3 studies for TTP399, an oral therapy for type 1 diabetes, which received Breakthrough Therapy Designation from the FDA. Recent phase 2 results showed significant HbA1c improvement and reduced hypoglycemia risk. Prasad brings over 20 years of healthcare experience, having previously led investments in prominent firms.

vTv Therapeutics announced positive results from a mechanistic study of TTP399, a treatment for type 1 diabetes (T1D), indicating it does not increase blood ketone levels during insulin withdrawal, minimizing the risk of ketoacidosis. Patients on TTP399 experienced improved fasting plasma glucose and fewer hypoglycemic events compared to placebo, with no incidents of hypoglycemia reported. The study, involving 23 participants, met its primary endpoint and sets the stage for a Phase 3 program expected to commence in early 2022.

vTv Therapeutics announced positive results from a multiple ascending dose study of HPP737, an orally administered PDE4 inhibitor, in healthy adults. The study showed a favorable safety profile without dose limiting gastrointestinal side effects. With a successful pre-IND meeting with the FDA, vTv plans to submit an IND application for a Phase 2 trial in moderate to severe psoriasis later this year, with the study set to begin in early 2022. These results suggest potential for HPP737 as a safer alternative for treating psoriasis.

vTv Therapeutics Inc. (Nasdaq:VTVT) reported its Q2 2021 financial results, highlighting a net loss of $608,000, significantly improved from a $4.2 million loss in Q1 2021. Cash reserves increased to $10.8 million. The company held a productive FDA meeting regarding its Breakthrough Therapy designation for TTP399, planning two pivotal studies to commence in early 2022. Revenue for Q2 was minimal at $9, with $2.4 million in R&D expenses. vTv announced a $50 million ATM equity program to support ongoing developments.

vTv Therapeutics, a clinical-stage biopharmaceutical company, announced it will present clinical data on HPP737, an orally administered PDE4 inhibitor for psoriasis, at the 6th World Psoriasis & Psoriatic Arthritis Conference from June 30 to July 3, 2021. The poster, titled Pharmacokinetics and Pharmacodynamics of HPP737, will be presented by Aaron Burstein, PharmD. HPP737 has shown strong efficacy and safety in clinical trials, making it a promising treatment option for psoriasis. More details will be available on vTv's website post-presentation.