Welcome to our dedicated page for Voyager Therapeutics news (Ticker: VYGR), a resource for investors and traders seeking the latest updates and insights on Voyager Therapeutics stock.
Voyager Therapeutics Inc (VYGR) is a leader in developing gene therapies for central nervous system disorders through its proprietary TRACER™ platform. This page provides investors and researchers with essential updates on clinical developments, strategic partnerships, and scientific breakthroughs in AAV-based treatments.
Access curated press releases and news articles covering key milestones in Voyager’s pipeline, including therapies for Parkinson’s disease, ALS, and Friedreich’s ataxia. Stay informed about advancements in blood-brain barrier penetration technology and preclinical validation studies across multiple species.
Our repository features updates on clinical trial progress, regulatory developments, and collaborative research initiatives. Discover analysis of vector optimization achievements and manufacturing scalability efforts critical to gene therapy commercialization.
Bookmark this page for consolidated access to verified information about Voyager’s neurogenetic innovations. Check regularly for objective reporting on therapeutic candidate progression and industry leadership in CNS-targeted gene delivery solutions.
Voyager Therapeutics (VYGR) has announced positive topline data from its single ascending dose (SAD) trial of VY7523, an anti-tau antibody designed to inhibit pathological tau spread in Alzheimer's disease. The trial, involving 48 healthy volunteers across six dose cohorts, demonstrated safety, tolerability, and dose-proportional pharmacokinetics.
Key findings include:
- No serious adverse events or infusion reactions reported
- Dose-proportionate increase in serum concentrations
- Cerebrospinal fluid-to-serum ratio of 0.3%, aligning with other approved AD antibodies
The company has initiated a multiple ascending dose (MAD) trial involving 52 patients with early Alzheimer's disease. This study will evaluate safety, tolerability, and VY7523's ability to prevent pathologic tau spread through PET imaging. Initial tau PET imaging data is expected in H2 2026.
Voyager Therapeutics (Nasdaq: VYGR), a biotechnology company focused on neurogenetic medicines, has announced its participation in two upcoming investor conferences in March 2025.
The company will attend the TD Cowen 45th Annual Health Care Conference in Boston, with a fireside chat scheduled for March 3, 2025, at 1:50 p.m. ET. Additionally, Voyager will participate in the Stifel 2025 Virtual CNS Forum, featuring a fireside chat on March 19, 2025, at 11:00 a.m. ET.
Webcasts of both presentations will be available through the Investors section of Voyager's website at ir.voyagertherapeutics.com. Interested parties can access replays of the webcasts, which will remain archived on the company's website for a minimum of 30 days after the events.
Voyager Therapeutics (VYGR) announced a setback in its SOD1 ALS gene therapy program, as three-month non-human primate data revealed the need to assess alternate payloads for VY9323. The siRNA payload component showed off-target effects, resulting in a narrowed therapeutic window. While the novel capsid component remains unchanged, the company will no longer file its planned IND application in mid-2025.
This development extends the company's cash runway into mid-2027, excluding potential milestone payments from partnerships. Despite this setback, Voyager maintains its timeline for other programs, including expected IND filings in 2025 for GBA1 Parkinson's and Friedreich's ataxia programs, and in 2026 for VY1706 (tau silencing) gene therapy program.
Voyager Therapeutics (Nasdaq: VYGR), a biotechnology company focused on neurogenetic medicines, has announced its participation in the Oppenheimer 25th Annual Healthcare Life Sciences Conference. The company will engage in a fireside chat scheduled for February 11, 2025, at 2:40 p.m. ET.
The presentation will be accessible via webcast through the Investors section of Voyager's website at ir.voyagertherapeutics.com. Interested parties can access a replay of the webcast, which will remain available on the company's website for a minimum of 30 days following the presentation.
Voyager Therapeutics (VYGR) has selected VY1706 as its lead development candidate for tau silencing gene therapy in Alzheimer's disease. The company plans to file IND and CTA applications in 2026. VY1706 combines siRNA technology to reduce tau expression with an IV-delivered TRACER capsid that can penetrate the blood-brain barrier. In non-human primate studies, a single VY1706 dose achieved 50% to 73% reduction in tau mRNA levels across the cerebral cortex, particularly in areas where tau accumulates during Alzheimer's progression. This marks the fifth neuro gene therapy development candidate using Voyager's TRACER capsids.
Voyager Therapeutics (VYGR) reported Q3 2024 financial results with collaboration revenue of $24.6 million, up from $4.6 million in Q3 2023. Net loss decreased to $9.0 million from $25.9 million year-over-year. The company completed enrollment in its VY7523 anti-tau antibody trial for Alzheimer's, with top-line data expected H1 2025. Voyager secured a new $15 million upfront payment from Novartis for a TRACER capsid license and received a $3 million milestone payment from Neurocrine. Cash position stands at $345.4 million, providing runway into 2027.
Voyager Therapeutics (VYGR) has announced its participation in four upcoming investor conferences in November 2024. The company will be present at the Truist Securities BioPharma Symposium in New York City (Nov 7), the Guggenheim Inaugural Healthcare Innovation Conference in Boston (Nov 13), the B. Riley Securities' Next-Gen Tissue Delivery Modalities Virtual Summit (Nov 14), and the Stifel 2024 Healthcare Conference in New York City (Nov 18).
Webcasts will be available for select conferences and can be accessed through Voyager's investor relations website, with replays available for at least 30 days.
Voyager Therapeutics (Nasdaq: VYGR), a biotechnology company focused on neurogenetic medicines, has scheduled its third quarter 2024 financial results announcement for Tuesday, November 12, 2024, after market close. The company will host a conference call and webcast at 4:30 p.m. ET on the same day. Investors can access the live webcast through the company's investor relations website, with a replay available for at least 30 days after the event.
Voyager Therapeutics (Nasdaq: VYGR) has announced the selection of a third gene therapy development candidate in collaboration with Neurocrine Biosciences. This candidate, targeting an undisclosed neurological disease, utilizes Voyager's TRACER™ capsid discovery platform for intravenous administration and blood-brain barrier penetration.
The selection triggers a $3 million milestone payment to Voyager, expected in Q4 2024. This follows previous nominations for Friedreich's ataxia and GBA1 Parkinson's disease. Voyager is eligible for additional development and commercialization milestone payments, plus royalties on potential future sales.
The collaboration, established in 2023, covers multiple neurological programs. For each undisclosed program, Voyager can receive up to $175 million in development milestones, commercial milestone payments, and tiered royalties on global net sales.
Voyager Therapeutics (Nasdaq: VYGR) has announced a new license agreement with Novartis AG (NYSE: NVS) for a novel capsid from Voyager's TRACER™ capsid discovery platform. The capsid will be used in a gene therapy program targeting an undisclosed rare neurologic disease. This agreement expands Voyager's partnered portfolio of TRACER-enabled gene therapies to 14 programs.
Key financial terms include:
- $15 million upfront payment to Voyager
- Up to $305 million in potential milestone payments
- Tiered mid- to high-single digit royalties on potential products
This marks the fifth gene therapy program in collaboration with Novartis, including Huntington's disease, spinal muscular atrophy, and three undisclosed indications.
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