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Whitehawk Therapeutics (Nasdaq: WHWK) announced on December 1, 2025 the appointment of Margaret Dugan, MD, as Chief Medical Officer.
Dr. Dugan brings more than 30 years of global oncology drug development experience, leadership in early-stage development, oversight of more than 12 Phase 1 programs, and involvement in regulatory approvals for multiple oncology drugs. She previously led early development at Novartis, served as CMO at Dracen Pharmaceuticals and Schrödinger, and advanced programs from proof-of-concept into clinical stages, including delivering three Phase 1 assets and moving a program to Phase 2 readiness in under 18 months. Whitehawk said the hire supports its plan to advance ADC programs toward clinical development.
Whitehawk Therapeutics (Nasdaq: WHWK) announced that Dave Lennon, PhD, President and CEO, will participate in a fireside discussion at the Piper Sandler 37th Annual Healthcare Conference in New York City on December 3, 2025 at 12:30 PM ET. A live webcast will be available on the company's investor relations website and will be replayable for approximately 30 days after the event.
Whitehawk Therapeutics (Nasdaq: WHWK) announced that Dave Lennon, PhD, President and CEO, will present at the Jefferies Global Healthcare Conference in London on November 18, 2025 at 11:30 AM GMT.
A live webcast of the presentation will be available via the company's investor relations website and will be available for replay for approximately 30 days following the event.
Whitehawk Therapeutics (Nasdaq: WHWK) reported Q3 2025 results and operational progress on Nov 6, 2025. Cash, cash equivalents and short-term investments were $162.6M as of Sept 30, 2025 versus $47.2M on Dec 31, 2024. The company reported a net loss of $17.7M for Q3 2025 vs. $12.5M for Q3 2024.
Whitehawk reaffirmed planned IND submissions for HWK-007 and HWK-016 by year-end 2025 and an IND for HWK-206 by mid-2026, stated runway into 2028, and presented PTK7 expression data at AACR-NCI-EORTC.
Whitehawk Therapeutics (Nasdaq: WHWK) presented a large real-world RNA analysis of PTK7 at AACR‑NCI‑EORTC on Oct 24, 2025. The study evaluated >157,000 tumor samples and found PTK7 expressed in ~70% of solid tumors, ranking PTK7 as the third most highly expressed ADC target after HER2 and HER3. Highest median PTK7 mRNA levels were reported in endometrial (7.4), ovarian (7.2), head and neck (7.1), NSCLC (6.9) and breast (6.7).
Expression was stable across histologic subtypes, disease stage and metastatic status. Whitehawk plans an IND filing for HWK‑007 (a PTK7‑directed ADC with a TOPO1 payload) by year‑end, targeting initial trials in NSCLC, ovarian and endometrial cancers.
Tempus (NASDAQ: TEM) announced a multi-year collaboration with Whitehawk Therapeutics (NASDAQ: WHWK) to use Tempus’ de-identified multimodal real-world dataset and AI platform to advance biomarker-driven oncology research.
The agreement will support Whitehawk’s clinical trial design and indication prioritization for its antibody drug conjugate (ADC) portfolio targeting PTK7, MUC16, and SEZ6, with a focus on cancers such as lung and gynecological indications. The partnership will evaluate concordance between RNA and IHC expression to explore RNA testing as an objective, reproducible, scalable alternative for patient identification.
Date announced: October 16, 2025.
Whitehawk Therapeutics (Nasdaq: WHWK), an oncology therapeutics company focused on ADC cancer treatments, has announced its upcoming participation in two major investor conferences. CEO Dave Lennon will engage in fireside chats at the Morgan Stanley Global Healthcare Conference on September 8, 2025 at 4:50 PM ET and the H.C. Wainwright Global Investment Conference on September 9, 2025 at 3:30 PM ET.
Both events will be held in New York City and will feature live webcasts accessible through Whitehawk's IR website, with replays available for approximately 30 days after the events.
Whitehawk Therapeutics (Nasdaq: WHWK), an oncology therapeutics company, reported Q2 2025 financial results and corporate updates. The company maintains a strong cash position of $177.2 million as of June 30, 2025, compared to $47.2 million at the end of 2024. The company reported a net loss of $52.6 million for Q2 2025.
Whitehawk is advancing its ADC portfolio with plans to file INDs for HWK-007 and HWK-016 by end of 2025, followed by HWK-206 in mid-2026. The current cash runway is expected to fund operations into 2028, supporting initial clinical data readouts across the portfolio.
Whitehawk Therapeutics (Nasdaq: WHWK), a company focused on developing advanced ADC cancer treatments, has announced its participation in the upcoming BTIG Virtual Biotechnology Conference. The conference is scheduled for July 29-30, 2025, where the company's management will present their developments in oncology therapeutics and ADC technology.