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Exagen Inc. Announces Select Preliminary 2025 Financial Results

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Exagen (Nasdaq: XGN) reported select preliminary unaudited results for the quarter and year ended December 31, 2025, consistent with prior guidance. Full-year revenue is projected at $66M–$67M, a 19%–20% increase versus 2024, and Q4 revenue is projected at $16M–$17M (up 17%–24%). The AVISE CTD test volume is 136,000–137,000 (TTM) with an ASP of $441–$445, an increase of at least $30 versus 2024. Year-end cash and cash equivalents were $32M, a $10M increase versus 2024. Results are preliminary and unaudited.

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Positive

  • Full-year revenue $66M–$67M (+19%–20% YoY)
  • Q4 revenue $16M–$17M (17%–24% YoY)
  • AVISE CTD TTM ASP $441–$445 (≥ $30 expansion)
  • AVISE CTD TTM volume 136,000–137,000 (+11% YoY)
  • Year-end cash $32M (+$10M vs 2024)

Negative

  • Results are preliminary unaudited and subject to audit adjustments
  • Company reported unexpected ASP headwinds in the second half of 2025

Key Figures

Q4 2025 revenue: $16M to $17M FY 2025 revenue: $66M to $67M Q4 YoY growth: 17% to 24% +5 more
8 metrics
Q4 2025 revenue $16M to $17M Three months ended Dec 31, 2025 (preliminary, unaudited)
FY 2025 revenue $66M to $67M Twelve months ended Dec 31, 2025 (preliminary, unaudited)
Q4 YoY growth 17% to 24% Revenue growth vs Q4 2024 (preliminary)
FY YoY growth 19% to 20% Revenue growth vs FY 2024 (preliminary)
AVISE CTD volume 136,000 to 137,000 tests Twelve months ended Dec 31, 2025
AVISE CTD TTM ASP $441 to $445 Trailing 12‑month average selling price, FY 2025
Year-end cash $32M Cash and cash equivalents at Dec 31, 2025
Cash increase $10M Increase in year-end cash vs 2024

Market Reality Check

Price: $4.74 Vol: Volume 428,973 is 1.3x th...
normal vol
$4.74 Last Close
Volume Volume 428,973 is 1.3x the 20-day average of 331,058. normal
Technical Price $6.34, trading below 200-day MA at $7.89 and 48.16% under 52-week high.

Peers on Argus

XGN was up 2.76% pre-news while key peers were mixed: MDXH +0.62%, PRE -7.28%, B...

XGN was up 2.76% pre-news while key peers were mixed: MDXH +0.62%, PRE -7.28%, BNR -0.85%, BDSX -4.21%, FONR -0.05%, pointing to a stock-specific setup.

Historical Context

5 past events · Latest: Nov 11 (Neutral)
Pattern 5 events
Date Event Sentiment Move Catalyst
Nov 11 Investor conferences Neutral -2.5% Participation in two November 2025 investor conferences in New York.
Nov 04 Earnings update Positive -9.0% Strong Q3 2025 results with $17.2M revenue and higher ASP and margins.
Oct 23 Scientific updates Positive +1.4% Acceptance of six abstracts and plenary presentation at ACR 2025.
Oct 21 Earnings call notice Neutral +0.5% Announcement of Q3 2025 results release date and conference call details.
Aug 06 Investor conferences Neutral +0.9% Planned participation in August and September 2025 investor conferences.
Pattern Detected

Earnings releases have often produced sizable but mixed reactions, including both strong rallies and selloffs on positive results.

Recent Company History

Over the last six months, Exagen has steadily highlighted growth in AVISE CTD volume, ASP, and revenue. Q4/FY 2024 results showed record revenue of $55.6M and ASP of $411. Through 2025, Q1–Q3 earnings updates reported record quarterly revenues around $15.5M–$17.2M, rising ASPs and higher cash balances. Today’s preliminary 2025 figures, including total revenue of $66M–$67M and year-end cash of $32M, connect directly to that earlier guidance of at least $65M in 2025 revenue.

Regulatory & Risk Context

Active S-3 Shelf · ≈ $8.5 million
Shelf Active
Active S-3 Shelf Registration 2025-06-20
≈ $8.5 million registered capacity

An effective Form S-3 dated Jun 20, 2025 registers up to 1,150,000 warrant-linked shares for resale, tied to a $75 million Perceptive term loan. The company receives no proceeds from stockholder resales, but cash only if the warrant is exercised, implying up to roughly 6.3% dilution alongside higher leverage.

Market Pulse Summary

This announcement outlines record preliminary 2025 revenue of $66M–$67M, year-over-year growth of 19...
Analysis

This announcement outlines record preliminary 2025 revenue of $66M–$67M, year-over-year growth of 19%–20%, AVISE CTD volume of 136,000–137,000 tests, and a trailing 12‑month ASP of $441–$445. Year-end cash of $32M marks a $10M increase over 2024, following prior guidance for at least $65M in 2025 revenue. Investors may monitor final audited results, ASP trends, test volume momentum, and any future use of the warrant-linked S-3 registration and term loan facility.

Key Terms

trailing 12-month (TTM)
1 terms
trailing 12-month (TTM) financial
"AVISE CTD Trailing 12-month (TTM) average selling price | $441 to $445"
Trailing 12-month (TTM) measures a company’s performance over the most recent 12 months by adding together the last four quarterly results or the most recent full-year plus interim reports. Investors use TTM to get an up-to-date view of revenue, profit or cash flow that smooths short-term swings — like looking back over the past year on a rolling window — which helps compare companies and value shares more accurately.

AI-generated analysis. Not financial advice.

CARLSBAD, Calif., Jan. 11, 2026 (GLOBE NEWSWIRE) -- Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing, today announced select preliminary unaudited financial results for the fourth quarter and year ended December 31, 2025, in line with prior financial guidance.

Select Preliminary Unaudited 2025 Results

 Revenue
 Three Months Ended
December 31, 2025
 Twelve Months Ended
December 31, 2025
Total Revenue$16M to $17M $66M to $67M
Year-Over-Year Growth17% to 24% 19% to 20%


 Other
 Twelve Months Ended
December 31, 2025
AVISE CTD Volume136,000 to 137,000
AVISE CTD Trailing 12-month (TTM) average selling price$441 to $445
Year-end cash and cash equivalents$32M
  

The select preliminary unaudited financial results reported today represent:

  • Record full year 2025 revenue, an increase of at least 19% over 2024
  • AVISE CTD trailing 12-month (TTM) ASP expansion by at least $30 compared to 2024
  • AVISE CTD test volume growth of at least 13,000, an 11% increase over 2024
  • Year-end cash and cash equivalents of $32 million, a $10 million increase over 2024

“I am pleased to report the completion of another strong year for Exagen in which we’ve continued to make substantial progress in building a great company; a testament to continued execution across our commercial, scientific, and operational teams,” said John Aballi, President and CEO. “Based upon our preliminary results, we delivered significant topline growth, driven by both volume and ASP expansion, despite unexpected ASP headwinds in the second half of the year. We also strengthened our scientific and commercial teams and subsequently launched our first enhancements to the AVISE platform in several years, with more on the horizon. Our strong cash position and disciplined approach provide the flexibility to continue to invest in innovation and advance our strategy to change the standard of care in autoimmune disease while pursuing our goal of operating a profitable company.”

Cautionary Note Regarding Select Preliminary Unaudited Financial Results

Exagen is providing the above select preliminary unaudited financial information and results of operations as of and for the three months and year ended December 31, 2025, based on currently available information. The company’s financial closing procedures with respect to the estimated financial data provided above are not yet complete. These procedures often result in changes to accounts. The company’s independent registered public accounting firm has not audited, reviewed, compiled or performed any procedures with respect to the select preliminary unaudited financial information and, accordingly, our independent registered public accounting firm does not express an opinion or any other form of assurance with respect thereto. As a result, the company’s final results may vary from the preliminary results presented above. Management undertakes no obligation to update or supplement the information provided above until it releases its audited financial statements prepared in accordance with U.S. Generally Accepted Accounting Principles (GAAP) for the year ended December 31, 2025.

About Exagen

Exagen Inc. (Nasdaq: XGN) is a leading provider of autoimmune diagnostics, committed to transforming care for patients with chronic and debilitating autoimmune conditions. Based in San Diego County, California, Exagen’s mission is to provide clarity in autoimmune disease decision making and improve clinical outcomes through its innovative testing portfolio. The company’s flagship product, AVISE® CTD, enables clinicians to more effectively diagnose complex autoimmune conditions such as lupus, rheumatoid arthritis, and Sjögren’s syndrome earlier and with greater accuracy. Exagen’s laboratory specializes in the testing of rheumatic diseases, delivering precise and timely results, supported by a full suite of AVISE-branded tests for disease diagnosis, prognosis, and monitoring. With a focus on research, innovation, education, and patient-centered care, Exagen is dedicated to addressing the ongoing challenges of autoimmune disease management.

For more information, please visit Exagen.com or follow @ExagenInc on X (formerly known as Twitter).

Forward Looking Statements

Exagen cautions you that statements contained in this press release regarding matters that are not historical facts are forward-looking statements. These statements are based on Exagen’s current beliefs and expectations. Such forward-looking statements include, but are not limited to, statements regarding: Exagen’s goals, strategies and ambitions; the potential utility and effectiveness of Exagen’s services and testing solutions, additional enhancements to the AVISE platform; potential shareholder value and growth and profitability; preliminary financial information for 2025. The inclusion of forward-looking statements should not be regarded as a representation by Exagen that any of its plans will be achieved. Actual results may differ from those set forth in this press release due to the risks and uncertainties inherent in Exagen’s business, including, without limitation: delays in reimbursement and coverage decisions from Medicare and third-party payors and in interactions with regulatory authorities, and delays in ongoing and planned clinical trials involving its tests; Exagen’s commercial success depends upon attaining and maintaining significant market acceptance of its testing products among rheumatologists, patients, third-party payors and others in the medical community; Exagen’s ability to successfully execute on its business strategies; third-party payors not providing coverage and adequate reimbursement for Exagen’s testing products, including Exagen’s ability to collect on funds due; Exagen’s ability to obtain and maintain intellectual property protection for its testing products; regulatory developments affecting Exagen’s business; and other risks described in Exagen’s prior press releases and Exagen’s filings with the Securities and Exchange Commission (SEC), including under the heading “Risk Factors” in Exagen’s Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on March 11, 2025, Quarterly Report on Form 10-Q for the quarter ended September 30, 2025 filed with the SEC on November 4, 2025 and any subsequent filings with the SEC. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and Exagen undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.

Contact:
Jeff Black, Chief Financial Officer
Exagen Inc.
ir@exagen.com


FAQ

What revenue did Exagen (XGN) preliminarily report for full-year 2025?

Exagen preliminarily reported $66M–$67M in total revenue for 2025, a 19%–20% increase versus 2024.

How much cash did Exagen (XGN) have at year-end 2025?

Year-end cash and cash equivalents were reported at $32 million, a $10 million increase versus 2024.

What were Exagen's (XGN) AVISE CTD volume and ASP for trailing 12 months 2025?

AVISE CTD TTM volume was 136,000–137,000 tests with a TTM ASP of $441–$445.

Did Exagen (XGN) meet its prior financial guidance for 2025?

The company said the select preliminary unaudited results are in line with prior financial guidance.

What Q4 2025 revenue range did Exagen (XGN) announce?

Exagen announced preliminary Q4 2025 revenue of $16M–$17M.

Are Exagen's 2025 results final and audited?

No, the figures announced are select preliminary unaudited results and may be adjusted upon audit.
Exagen Inc.

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