Zymeworks Inc. develops and manages licensed healthcare assets while advancing a pipeline of novel, multifunctional biotherapeutics for oncology. Company news centers on Ziihera (zanidatamab-hrii) and zanidatamab-related regulatory and clinical updates, including HER2-targeted development, as well as ZW191, a folate receptor alpha-targeting antibody-drug conjugate with Fast Track designation for advanced or metastatic platinum-resistant ovarian cancer.
Recurring updates also cover antibody-drug conjugate platform work, including RAS inhibitor ADC programs and targets such as CLDN18.2, Ly6E and PTK7, along with financial results, cash resources, share repurchase activity, investor conference participation and executive leadership appointments.
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Zymeworks Inc. (Nasdaq: ZYME) presented new data from its clinical and preclinical programs at the 2023 American Association for Cancer Research Annual Meeting. Key highlights include:
- ZW191 showed strong responses in FRα-low expressing patient-derived xenograft models, with positive pharmacokinetic and safety profiles.
- ZW171 effectively killed cancer cells while mitigating risks of toxicity and adverse immune activation.
- ZW251 demonstrated significant anti-tumor activity in various glypican-3-expressing cancer models.
The company aims to advance at least five novel therapeutics into clinical studies by 2027, bolstered by their innovative antibody-drug conjugates and multispecific antibody platforms.
Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company focused on developing innovative biotherapeutics, will report its Q1 2023 financial results on May 8, 2023, after market close. Following this announcement, Zymeworks will host a conference call and webcast at 4:30 p.m. ET on the same day to discuss the results and provide a corporate update. Investors can access the live event and recordings through Zymeworks’ website.
Founded with a mission to address challenging cancers and other serious diseases, Zymeworks specializes in antibody-based therapies using its proprietary Azymetric™ technology. The company is advancing its lead candidate, zanidatamab, and next-generation product zanidatamab zovodotin (ZW49), both targeting HER2-expressing cancers.
Zymeworks Inc. (Nasdaq: ZYME) announced the appointment of Derek J. Miller to its board of directors effective April 10, 2023. Miller brings over 25 years of experience in oncology and corporate development. His expertise is expected to support Zymeworks in its collaboration efforts with Jazz Pharmaceuticals and BeiGene on zanidatamab, a bispecific antibody currently undergoing multiple clinical trials. Kenneth Galbraith, CEO, emphasized Miller's strategic insights will enhance the company's pipeline of drug candidates. Miller's previous roles include leadership positions at Aro Biotherapeutics and Celator Pharmaceuticals, where he contributed to significant collaborations and business strategies that generated substantial revenues. Zymeworks focuses on developing innovative biotherapeutics aimed at improving outcomes for patients with difficult-to-treat cancers.