Company Description
Alphatec Holdings, Inc. (Nasdaq: ATEC) is a medical device company focused on the surgical treatment of spinal disorders. According to the company, ATEC is dedicated to revolutionizing the approach to spine surgery through clinical distinction, with a spine-only focus and a vision "to be the Standard Bearer in Spine." Through its wholly owned subsidiaries Alphatec Spine, Inc., EOS imaging S.A.S., and SafeOp Surgical, Inc., the company develops and commercializes technologies intended to make spine surgery more informed, reproducible, and outcome-driven.
Alphatec is described as a spine-focused provider of solutions that support procedures addressing complex pathologies of the thoracolumbar spine and other spinal conditions associated with disease, degeneration, deformity, trauma, tumor, infection, and related indications. Earlier descriptions also note that the company designs, develops, and advances products for the surgical treatment of spinal disorders, including approaches such as Posterior Cervical Fusion, Anterior Cervical Discectomy and Fusion, Lateral Interbody Fusion, and Posterior Lumbar Interbody Fusion.
Spine-focused procedural ecosystems
ATEC emphasizes a procedural, ecosystem-based approach to spine surgery. Management frequently refers to an "end-to-end procedural ecosystem" and "procedural spine solutions" that integrate data, informatics, imaging, navigation, and instrumentation. The company highlights that its solutions are architected to drive clinical distinction and more predictable surgical outcomes, with particular attention to complex spine surgeries.
A core element of this strategy is the Organic Innovation Machine™, which the company describes as its engine for developing new approaches that integrate seamlessly with its expanding informatics platforms. These platforms are referenced as InformatiX™ and AlphaInformatiX in company communications and are intended to better inform surgery and more safely and reproducibly achieve the goals of spine surgery.
Key platforms, technologies, and subsidiaries
Alphatec operates through several specialized subsidiaries and technology platforms:
- Alphatec Spine, Inc. – The primary spine business, focused on procedural spine solutions and surgical technologies.
- EOS imaging S.A.S. – Referenced as contributing EOS revenue and associated with EOS Insight®, which the company notes is seeing increased adoption. EOS-related offerings are integrated into ATEC’s spine ecosystem and reported as a distinct revenue component.
- SafeOp Surgical, Inc. – Associated with the SafeOp™ Neural InformatiX™ System, which is described as delivering objective and actionable information through neurophysiologic monitoring capabilities such as motor evoked potentials (MEPs), surgeon-directed Delta™ tEMG for lumbar plexus localization, and real-time femoral nerve health monitoring with automated SSEPs.
ATEC also highlights proprietary approaches and systems within its procedural portfolio. For example, its Prone TransPsoas (PTP™) and Lateral TransPsoas (LTP™) approaches are cited as key drivers of surgical revenue growth and surgeon adoption. The company describes PTP as part of a fully integrated offering that includes positioning, access, implants, and neuro-monitoring.
PTP™ Corpectomy and complex spine solutions
Alphatec has announced the commercial launch of its PTP™ Corpectomy system, which it characterizes as the next evolution of lateral approach surgery. This system extends the PTP approach to deformity and corpectomy procedures for complex thoracolumbar pathologies, including cases involving tumor, trauma, infection, and deformity.
The PTP Corpectomy solution, as described by the company, includes:
- Sigma™ LIF Corpectomy Access System – Designed to optimize lateral corpectomy exposure of the thoracolumbar spine, with retractor versatility and customizable exposure in prone (PTP) and lateral decubitus (LTP™) positions.
- Ascend™ NanoTec™ Vertebral Body Replacement (VBR) System – An expandable, anatomy-driven vertebral body replacement system with NanoTec surface treatment technology intended to enhance bone growth in complex spinal reconstruction.
- SafeOp™ Neural InformatiX™ System – Providing intraoperative neurophysiologic information to support safer lateral corpectomy and other spine procedures.
These systems are presented as working together within ATEC’s integrated PTP offering, with the goal of improving access, minimizing risk, and supporting better patient outcomes in complex spine surgeries.
Biologics and regenerative medicine partnership
Alphatec has entered into a definitive strategic partnership with Theradaptive, Inc., a clinical-stage regenerative medicine company. Under this agreement, ATEC gains exclusive U.S. commercial rights to market and distribute OsteoAdapt®, an osteoinductive bone graft for spinal fusion that is built on Theradaptive’s proprietary AMP2™ protein technology. The companies describe OsteoAdapt as being evaluated in clinical trials in spine and dental applications and subject to FDA PMA approval, with three FDA Breakthrough Device Designations.
ATEC characterizes this partnership as an important milestone in the evolution of its procedural ecosystem, adding a biologic solution intended to enhance fusion outcomes. Company communications describe OsteoAdapt as a next-generation rhBMP-2 solution designed to deliver potent bone formation with greater precision at the fusion site, enabling lower doses, simpler handling, and an improved safety profile versus legacy biologics, and to address market concentration in the rhBMP-2 segment.
Revenue mix and growth drivers (structural, not numeric)
While specific financial figures change over time, ATEC’s public disclosures provide insight into how its business is structured. The company reports revenue in at least two primary categories: surgical revenue and EOS revenue. Surgical revenue is associated with spine procedures and related technologies, while EOS revenue is tied to EOS imaging-related offerings.
Management commentary emphasizes several recurring growth drivers:
- Surgical volume growth and average revenue per procedure, reflecting adoption of ATEC’s procedural solutions.
- New surgeon adoption and growth in net new surgeon users, cited as key leading indicators of future growth.
- Expansion of procedural ecosystems such as PTP and LTP, and increased adoption of EOS Insight®.
- Integration of biologics like OsteoAdapt into the company’s procedural offerings.
The company also regularly discusses non-GAAP measures such as adjusted EBITDA, non-GAAP gross margin, and free cash flow, which it presents as tools for evaluating core operating performance and capital efficiency.
Capital markets presence and communications
Alphatec’s common stock trades on the Nasdaq exchange under the ticker symbol ATEC. The company frequently participates in healthcare and medical technology conferences, including events hosted by organizations such as J.P. Morgan, North American Spine Society, and various investment banks. It also regularly hosts webcasts to discuss quarterly financial results and outlook.
ATEC uses current reports on Form 8-K to furnish press releases related to financial results and other material events, including quarterly earnings announcements and board-related matters. For example, Form 8-K filings reference press releases announcing financial results for periods ended June 30 and September 30, 2025, and a separate filing notes a press release regarding the passing of a board member.
Corporate focus and vision
Across its communications, Alphatec consistently describes itself as a spine-only company with a singular focus on spine surgery. Management commentary highlights the company’s intent to architect procedural solutions that integrate data, informatics, imaging, navigation, instrumentation, and biologics to improve predictability and outcomes in spine care. The company positions its culture and operations around this focus, referring to itself as "spine’s most relentless, deeply committed stewards" and emphasizing a long-term commitment to shaping standards in spine surgery.
FAQs about Alphatec Holdings, Inc. (ATEC)
- What does Alphatec Holdings, Inc. do?
Alphatec Holdings, Inc. is a medical device company focused on spine surgery. Through subsidiaries such as Alphatec Spine, Inc., EOS imaging S.A.S., and SafeOp Surgical, Inc., it develops and commercializes procedural spine solutions, imaging technologies, neuro-monitoring systems, and related offerings intended to improve the safety, reproducibility, and outcomes of spinal procedures.
- What is ATEC’s primary industry and sector?
ATEC operates in the medical device space with a focus on spinal surgery technologies. It is associated with surgical and medical instrument manufacturing within the broader manufacturing sector.
- How does Alphatec describe its business strategy?
The company describes its strategy as building an end-to-end procedural ecosystem for spine surgery, driven by its Organic Innovation Machine™ and integrated with its InformatiX™ and AlphaInformatiX platforms. This strategy emphasizes clinical distinction, data and informatics integration, and spine-only focus.
- What are PTP™ and LTP™ in ATEC’s product ecosystem?
PTP™ (Prone TransPsoas) and LTP™ (Lateral TransPsoas) are spine surgical approaches referenced by ATEC as important components of its procedural ecosystem. The company notes that PTP and LTP are driving surgical revenue growth and surgeon adoption, and that PTP Corpectomy extends these approaches to complex thoracolumbar pathologies.
- What is the PTP™ Corpectomy system?
The PTP Corpectomy system is a commercial offering that ATEC describes as the next evolution of its lateral approach surgery. It includes the Sigma™ LIF Corpectomy Access System, the Ascend™ NanoTec™ Vertebral Body Replacement System, and the SafeOp™ Neural InformatiX™ System, all designed to work together to support lateral corpectomy and complex thoracolumbar procedures.
- What role does EOS imaging play in ATEC’s business?
EOS imaging S.A.S. is a wholly owned subsidiary of ATEC. The company reports EOS revenue as a distinct category and notes that EOS Insight® adoption is increasing. EOS-related technologies are integrated into ATEC’s spine ecosystem and contribute to its overall revenue mix.
- What is the significance of the Theradaptive partnership?
ATEC has entered into a strategic partnership with Theradaptive, Inc. that grants ATEC exclusive U.S. commercial rights to OsteoAdapt®, an osteoinductive bone graft for spinal fusion built on AMP2™ protein technology. The partnership is described as a landmark regenerative medicine collaboration for the spine industry and is intended to integrate a next-generation rhBMP-2 biologic into ATEC’s procedural offerings.
- How does Alphatec use data and informatics in spine surgery?
ATEC’s communications emphasize that its procedural solutions are supported by data and informatics, integrated through platforms such as InformatiX™ and AlphaInformatiX. The goal is to better inform surgical decision-making and more safely and reproducibly achieve the objectives of spine surgery.
- On which exchange does ATEC stock trade and under what symbol?
Alphatec Holdings, Inc. common stock trades on the Nasdaq exchange under the ticker symbol ATEC.
- How does Alphatec present its financial performance?
The company reports GAAP financial results and also provides non-GAAP measures such as non-GAAP gross margin, non-GAAP operating expenses, adjusted EBITDA, and free cash flow. It explains that these non-GAAP metrics are used by management to evaluate core performance and capital efficiency, and it provides definitions and reconciliations in its public disclosures.