Company Description
Hansa Biopharma AB is a pioneer in immunoglobulin G (IgG)-cleaving enzyme technology, developing innovative treatments for rare immunological conditions. With conditional marketing approval in Europe, their unique antibody-cleaving enzyme, imlifidase, targets IgG and inhibits IgG-mediated immune response. The recent 16-HMedIdeS-12 phase 2 trial demonstrated that imlifidase significantly reduced donor-specific antibodies (DSAs) in patients with antibody-mediated rejection (AMR) episodes following a kidney transplant. The trial showcased a 94.4% reduction in DSAs compared to standard of care, highlighting the potential of imlifidase in improving patient outcomes. In addition to kidney transplants, Hansa Biopharma is exploring the use of imlifidase in autoimmune diseases such as anti-glomerular basement membrane (anti-GBM) disease, Guillain-Barré Syndrome, and ANCA-associated vasculitis.
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