Company Description
Hologic, Inc. (Nasdaq: HOLX) is a medical technology company primarily focused on improving women’s health and well-being through early detection and treatment of disease. According to company disclosures and recent press releases, Hologic develops medical technologies that are designed to effectively detect, diagnose and treat health conditions and to raise the standard of care around the world. The company is headquartered in Marlborough, Massachusetts and its common stock is listed on The Nasdaq Stock Market LLC under the symbol HOLX.
Hologic reports that it manufactures proprietary products for the healthcare needs of women and operates through several business areas. Based on its own descriptions and financial reporting, these include diagnostics, breast health, GYN surgical and skeletal health. Historically, the company has highlighted four segments: diagnostics, breast health, surgical and skeletal health. Diagnostics encompasses cytology and perinatal testing, molecular diagnostics and blood screening. Breast health includes breast imaging systems and interventional breast solutions. GYN surgical covers products used in gynecologic procedures, and skeletal health relates to technologies used to assess bone and related conditions.
In its diagnostics business, Hologic emphasizes molecular and cytology-based testing that supports women’s health and infectious disease detection. The company has described a fully automated Panther System and Panther Fusion module as molecular diagnostics platforms that consolidate a menu of assays for women’s health, sexually transmitted infections, respiratory infections, viral load, transplant viruses and infectious gastroenteritis. Hologic has announced FDA clearance and CE marking in the European Union for Panther Fusion Gastrointestinal Bacterial and Expanded Bacterial Assays, which are designed to detect common bacterial pathogens responsible for infectious gastroenteritis and can be run in customizable mini-panel formats.
Hologic’s breast health business includes imaging and interventional technologies for breast cancer screening and diagnosis. The company has publicized digital breast tomosynthesis (3D mammography) systems and AI-powered tools such as its Genius AI Detection solution, which is described as a mammography screening technology designed to locate lesions likely to represent breast cancer and to highlight suspicious areas at radiologists’ workstations. Hologic has also discussed 3DQuorum imaging technology, which uses artificial intelligence to reduce the number of 3D imaging slices radiologists need to review while maintaining cancer detection performance, with the goal of streamlining radiologists’ workflows.
Beyond imaging, Hologic has expanded into digital pathology. The company has announced that its Genius Digital Diagnostics System has achieved expanded CE marking in the European Union, allowing European laboratories to digitize and review both cell and tissue specimens. Hologic states that this system uses volumetric imaging technology to convert glass slides into high-resolution digital images, capturing multiple layers of a specimen and converting them into a single two-dimensional view. The system is intended to support pathology workflows across a variety of specimen types, including those used in cervical and breast cancer diagnosis, and to enable secure storage, distribution and remote review of cases.
In oncology diagnostics, Hologic and its subsidiary Biotheranostics, Inc. have highlighted the Breast Cancer Index (BCI) Test, which is described as a molecular, gene expression-based test for patients with early-stage, hormone receptor–positive breast cancer. According to company communications, the BCI Test is intended to help physicians individualize treatment decisions, particularly around extended endocrine therapy duration. Hologic notes that the test has guideline designation from the American Joint Committee on Cancer for cancer staging based on molecular profile and is acknowledged in certain clinical practice guidelines as a biomarker to help inform extended endocrine treatment decisions.
Hologic also operates in the GYN surgical and skeletal health categories. In its financial reporting, the company identifies GYN surgical revenue and skeletal health revenue separately from diagnostics and breast health, indicating distinct product and service lines in these areas. While individual product names within these segments are referenced in earnings materials, the overarching theme is support for gynecologic procedures and assessment of skeletal conditions as part of the company’s broader focus on women’s health.
Geographically, Hologic has stated that it serves customers in the United States and international markets, with revenue reported for U.S. and international regions. Earlier descriptions note that the United States accounts for the largest portion of the firm’s revenue, followed by Europe, Asia and other international markets. The company characterizes itself as a global leader in women’s health, with technologies and diagnostic solutions used by laboratories and healthcare providers in multiple regions.
Hologic’s activities extend beyond product development to education and awareness. For example, the company has launched the "Ultimate Defense" educational campaign in the United States with professional basketball player Erica Wheeler, focused on encouraging routine cervical cancer screening and conversations between women and their healthcare providers about Pap and HPV testing. This type of initiative reflects Hologic’s stated commitment to combining technology with patient education to support early detection and prevention of cervical cancer.
The company also participates in research collaborations and scientific conferences. It has announced multiple studies of its AI-powered mammography solutions, including retrospective analyses of digital breast tomosynthesis exams using the Genius AI Detection solution and large-scale evaluations of 3DQuorum imaging technology. In addition, Hologic and Biotheranostics have reported numerous investigational studies featuring the Breast Cancer Index Test at the San Antonio Breast Cancer Symposium, covering topics such as recurrence risk, extended endocrine therapy benefit, and performance across different patient populations and sample types.
Hologic’s portfolio includes epigenomics and life sciences services through subsidiaries such as Hologic Diagenode, which is described as a provider in the field of epigenomics with services that can support biomarker discovery and validation by combining epigenomics and bioinformatics. Hologic has also entered into a co-marketing and services agreement with VolitionRx Limited to co-market Nu.Q Discover services to Hologic customers, reflecting the company’s involvement in pharmaco-epigenetics research support.
From a corporate and capital markets perspective, Hologic has reported that it is a Delaware corporation with common stock registered under Section 12(b) of the Securities Exchange Act of 1934 and traded on Nasdaq. In an Agreement and Plan of Merger disclosed in an 8-K filing and accompanying press release, Hologic announced that it entered into a definitive agreement to be acquired by funds managed by Blackstone and TPG. Under the terms described, a merger subsidiary will merge with and into Hologic, with Hologic surviving as a wholly owned subsidiary of a parent entity affiliated with these funds. Upon completion of the transaction, Hologic’s common stock is expected to be delisted from the Nasdaq Stock Market and deregistered under the Exchange Act, while the company maintains its headquarters in Marlborough, Massachusetts and continues to operate under the Hologic name and brand.
Hologic’s financial communications describe revenue contributions from diagnostics, breast health, GYN surgical and skeletal health, and detail organic revenue metrics that exclude certain divested businesses and COVID-19 related revenue. The company also reports non-GAAP financial measures, such as adjusted EBITDA, non-GAAP gross margin and non-GAAP EPS, and explains the adjustments used to derive these metrics. These disclosures are intended to provide additional perspective on operating performance beyond generally accepted accounting principles.
Across its disclosures, Hologic consistently characterizes itself as focused on developing medical technologies that support early detection, diagnosis and treatment, particularly in women’s health. Its activities span imaging, molecular diagnostics, digital pathology, oncology biomarkers, gynecologic surgery and skeletal health, along with educational campaigns and scientific research collaborations. Investors researching HOLX stock can reference the company’s SEC filings, press releases and segment reporting to understand how these areas contribute to Hologic’s overall business.