Company Description
Revium Rx (trading under the symbol RVRC and formerly known as Revium Recovery Inc.) is a preclinical-stage biotechnology company that focuses on lipid-based and nanoparticle-formulated therapeutics. According to company disclosures, Revium Rx is developing medicines for high-need indications, with an emphasis on antimicrobial resistance and solid tumors. Its common stock is quoted and traded on an OTC Markets tier under the symbol RVRC.
Business focus and therapeutic areas
Revium Rx describes itself as a biotechnology company advancing lipid-based and nanoparticle-formulated therapeutics. The company states that it focuses on treatments for antimicrobial resistance and solid tumors, aiming to improve how medicines behave in the body. Its approach is based on encapsulated therapeutics that use lipid-based carriers and nanoparticle technologies to influence drug delivery, stability, and exposure.
Following its acquisition of LipoVation Ltd., an Israeli development-stage company specializing in lipid-based nano/micro particle medicines, Revium Rx shifted its focus toward nanoparticle-based therapeutics. LipoVation’s core technology was conceptualized by Prof. Yehezkel Barenholz, who is identified as the inventor of Doxil, an FDA‑approved liposomal chemotherapy drug. After the transaction, LipoVation became a wholly owned subsidiary of Revium Rx, and the combined company emphasized drug delivery innovation using lipid and nanoparticle platforms.
Pipeline and lead programs
Revium Rx reports that it is building a portfolio of development-stage therapeutics intended to expand the potential of existing treatments. Public information highlights several key programs:
- A novel systemic formulation of a highly potent antibiotic that was previously limited to topical use, designed to address antibiotic-resistant bacterial infections.
- An adjuvant program intended to enhance immune checkpoint inhibitors and improve the performance of cancer immunotherapies.
- An immunization approach that uses novel peptides and lipid-based technology for emerging infectious diseases.
The company’s lead product candidate is identified as Nano‑Mupirocin, described as a systemic formulation of the well-known antibiotic mupirocin. Revium Rx states that Nano‑Mupirocin is designed to overcome mupirocin’s instability in blood and to extend its use from topical applications to systemic treatment for severe bacterial infections. The formulation is intended to maintain therapeutic concentrations in the bloodstream and to target deep-tissue infections caused by multidrug-resistant pathogens such as Methicillin‑Resistant Staphylococcus aureus (MRSA), Vancomycin‑Resistant Enterococci (VRE), and Ceftriaxone‑Resistant Neisseria gonorrhoeae.
According to company announcements, Revium Rx has advanced regulatory and manufacturing work in support of a planned Phase 1 clinical trial of Nano‑Mupirocin. The company has reported submitting a clinical trial application to the Israeli Ministry of Health and working with WuXi AppTec on scale‑up and production of a GMP clinical batch.
Technology platform
Revium Rx attributes its programs to three core proprietary technology areas described in its public communications:
- Clinically validated nanoparticles for targeted drug delivery.
- Advanced drug-loading and release systems intended to optimize bioavailability.
- Specialized lipid-based carriers designed for enhanced stability and controlled release.
These technologies are used to create encapsulated therapeutics that the company positions as smarter and more targeted treatments. Revium Rx states that its goal is to increase the effectiveness of medicines while reducing side effects by improving how drugs are delivered and distributed in the body.
Corporate evolution and listing
The company’s SEC registration statements describe Revium Rx as a Nevada corporation and note that it was formerly known as Revium Recovery Inc. The filings also indicate that Revium Rx is an emerging growth company and a smaller reporting company under U.S. securities regulations. The company has filed an S‑1 registration statement and subsequent amendments for an initial public offering of units consisting of common stock and warrants, along with a resale registration for existing stockholders.
In these filings, Revium Rx explains that it is conducting a self‑underwritten public offering of units and registering additional shares for resale by selling stockholders. The company notes that its common stock is quoted and traded on an OTC Markets tier under the symbol RVRC and that it has used an alternative reporting standard permitted by OTC Markets prior to the S‑1 registration process.
Position within healthcare and biotechnology
Although external industry classifications may place the legacy entity in health information services, Revium Rx’s own descriptions present it as a biotechnology and biopharmaceutical company. Its focus is on lipid-based and nanoparticle-formulated therapeutics, antimicrobial resistance, solid tumors, cancer immunotherapy enhancement, and emerging infectious disease immunization approaches. The acquisition of LipoVation and the emphasis on liposomal and nanoparticle technologies reflect a concentration on drug delivery science within the broader healthcare and pharmaceutical sector.
Investment and regulatory profile
Through its S‑1/A filings, Revium Rx has outlined a capital-raising structure that includes units of common stock and warrants in a best‑efforts offering, alongside a resale registration for existing shareholders. The company highlights risks typical for early-stage biotechnology issuers, including the possibility of losing an entire investment, and directs readers to risk factor discussions in its prospectus. As an emerging growth company and smaller reporting company, it indicates that it is subject to specific reporting and accounting standards defined by U.S. securities law.
Summary
In summary, Revium Rx (RVRC) is a Nevada-incorporated, preclinical-stage biotechnology company that has transitioned from its prior Revium Recovery identity into a business centered on lipid-based and nanoparticle-formulated therapeutics. With a lead systemic antibiotic candidate, Nano‑Mupirocin, and additional programs in cancer immunotherapy support and immunization technologies, the company positions its pipeline around antimicrobial resistance, solid tumors, and emerging infectious diseases. Its shares trade on an OTC Markets tier, and it has pursued an initial public offering and resale registration through S‑1/A filings with the SEC.