Company Description
10x Genomics, Inc. (NASDAQ: TXG) is a life science technology company that develops products to help researchers analyze biological systems at high resolution and scale. The company focuses on single cell and spatial biology, providing integrated research solutions that combine instruments, consumables and software. These solutions are used by academic and translational researchers and biopharmaceutical companies to study complex biological systems in areas such as oncology, immunology and neuroscience.
According to its public disclosures, 10x Genomics’ integrated platforms are designed to help users understand biological systems at a resolution and scale that matches the complexity of biology. The company states that its products have been used in research that has led to breakthroughs in oncology, immunology, neuroscience and other fields, contributing to a deeper understanding of health and disease.
Business focus and technology platforms
10x Genomics describes itself as building research products to accelerate the mastery of biology and advance human health. Its integrated research solutions include:
- Instruments for single cell and spatial biology, including Chromium and spatial platforms referenced in company materials.
- Consumables that support these instruments, such as reagents and assays used in single cell and spatial workflows.
- Software that enables analysis of the high-dimensional data generated by these platforms.
The company highlights its Chromium single cell platform and Visium and Xenium spatial platforms in its descriptions and financial disclosures. Chromium instruments and consumables are used for single cell analysis, while Visium and Xenium products are categorized as spatial products in the company’s reported revenue breakdowns. The company also reports that it offers services and license and royalty revenue associated with its technologies.
Single cell biology solutions
10x Genomics positions itself as a leader in single cell biology. Its public statements describe multiple single cell offerings, including:
- Chromium single cell instruments, used to run single cell assays.
- Chromium Flex, described as a next-generation, cost-effective, highly scalable, plate-based single cell analysis solution that enables researchers to explore a broad range of studies.
- GEM-X 3' assay, an assay designed for single cell analysis that the company states can provide high cell capture and higher gene sensitivity compared to alternative non-10x methods.
- Chromium X and Chromium Xo, with Chromium Xo described as a lower-cost single cell instrument that offers an entry point into routine, high-performance single cell analysis and a path to upgrade to Chromium X.
The company states that its Chromium instruments are designed to automate and scale single cell workflows, including automation to partition large numbers of cells in minutes and an interface intended to streamline cell processing. According to company communications, these instrument-powered workflows are intended to improve data quality, sample recovery, reproducibility and scalability compared to manual, instrument-less single cell methods.
Spatial biology solutions
10x Genomics also emphasizes its role in spatial biology. In its financial reporting, it identifies Visium and Xenium as spatial products. The company has announced:
- The Xenium spatial platform, used in initiatives such as the Asia-Pacific Spatial Translational Research Alliance (ASTRA), which plans to build a pan-cancer spatial atlas across thousands of tumor samples.
- Xenium Protein, described as a fully integrated spatial multiomic workflow that enables simultaneous RNA and protein detection on the same tissue section in a single automated run.
These spatial platforms are used in collaborations to generate molecularly detailed maps of tissues and tumors, integrating cellular composition and spatial architecture. Company announcements describe how these platforms can be applied to study tumor microenvironments, immune context and other spatial features relevant to disease and therapy response.
Applications in human health research
Across its public materials, 10x Genomics highlights that its technologies are used in research related to:
- Oncology, including tumor profiling, biomarker discovery and studies of treatment response and resistance.
- Immunology, including immune cell profiling and studies of immune responses in cancer, autoimmune disease and transplantation.
- Neuroscience, where single cell and spatial approaches are applied to understand complex neural systems.
The company describes collaborations with leading academic medical centers and research organizations to apply its platforms in large-scale translational studies. Examples in public announcements include collaborations focused on autoimmune diseases, solid tumors, immuno-oncology and transplant rejection, where 10x Genomics’ single cell and spatial technologies are used to generate high-resolution molecular data.
Customer base and research collaborations
10x Genomics states that its customers include academic and translational researchers and biopharmaceutical companies. The company’s announcements reference collaborations with institutions such as Brigham and Women’s Hospital, Dana-Farber Cancer Institute, the Cancer Research Institute, the Garvan Institute of Medical Research, the University of Tokyo and CareDx. These collaborations are described as using 10x Genomics’ Chromium and Xenium platforms, as well as assays like Chromium Flex, to generate large-scale single cell and spatial datasets in areas such as autoimmune disease, oncology, immuno-oncology and transplantation.
In these collaborations, 10x Genomics’ technologies are used to profile immune cells, tumor microenvironments and tissue-level immune architecture, often combining single cell and spatial data with clinical information. The company states that such efforts aim to identify immune signatures, biomarkers and molecular features associated with disease activity, treatment response, resistance and disease progression, and to inform potential future diagnostic and clinical applications.
Geographic reach and revenue mix
In its financial disclosures, 10x Genomics reports revenue from multiple regions, including the United States, other parts of the Americas, Europe, the Middle East and Africa, China and the broader Asia-Pacific region. The company categorizes revenue into instruments, consumables, services, and license and royalty revenue, and further distinguishes between single cell (Chromium) and spatial (Visium and Xenium) products.
The company has reported that it has sold thousands of Chromium instruments and a substantial number of spatial instruments, and that single cell consumables reactions have increased compared to prior periods. These disclosures indicate an installed base of instruments and ongoing usage of consumables across its customer base.
Regulatory filings and public communications
10x Genomics’ Class A common stock trades on The Nasdaq Stock Market LLC under the symbol TXG. The company files reports with the U.S. Securities and Exchange Commission (SEC), including Forms 10-K, 10-Q and 8-K. In its press releases, 10x Genomics notes that it uses SEC filings, its website, press releases, public conference calls, public webcasts and social media accounts as channels for disclosing information, including material non-public information, in accordance with Regulation FD.
Recent Form 8-K filings have covered topics such as quarterly financial results and changes in certain executive roles. These filings confirm the company’s status as a Nasdaq-listed issuer and provide additional detail on its financial condition and corporate governance matters.
Sector and industry context
Within the broader economy, 10x Genomics is classified in the Professional, Scientific, and Technical Services sector, in the Testing Laboratories industry. At the same time, the company describes itself as a life science technology company, emphasizing its role in providing research products—rather than clinical services—to laboratories and institutions engaged in biological and medical research.
By focusing on single cell and spatial biology, 10x Genomics operates in a specialized area of life science tools and technologies. Its products are designed to generate high-dimensional molecular data that can be used to study complex biological questions, with the stated goal of accelerating discoveries that may advance human health.
Use cases and research impact
Company communications repeatedly state that 10x Genomics’ products are behind research breakthroughs in oncology, immunology, neuroscience and other fields. Examples described in public materials include:
- Studies of autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and giant cell arteritis, where single cell profiling of blood is used to identify immune signatures of disease activity and treatment response.
- Research in solid tumors, where single cell and spatial profiling of tumor samples is used to study therapeutic targets, tumor microenvironment features and biomarkers associated with treatment response or resistance.
- Large-scale immuno-oncology initiatives that combine single cell and spatial data with artificial intelligence to map immune responses to cancer and inform future immunotherapies and vaccines.
- Transplant research collaborations that use spatial and single cell platforms to study organ rejection, microvascular inflammation and therapeutic response.
In these contexts, 10x Genomics’ technologies are used as research tools to generate detailed molecular maps of cells and tissues, which can then be analyzed to uncover patterns and mechanisms relevant to disease and therapy.
Position within capital markets
As a publicly traded company on Nasdaq under the symbol TXG, 10x Genomics is followed by investors interested in life science technology and research tools. The company provides regular financial updates through earnings releases and conference presentations, and has participated in investor conferences such as the J.P. Morgan Healthcare Conference and the Wolfe Research Healthcare Conference. Its disclosures include information on revenue by product type and geography, gross margin, operating expenses, cash and marketable securities, and other financial metrics.
Frequently Asked Questions (FAQ)
- What does 10x Genomics, Inc. do?
10x Genomics is a life science technology company that develops instruments, consumables and software for single cell and spatial biology. Its products are used by researchers to analyze biological systems at high resolution and scale in fields such as oncology, immunology and neuroscience. - How does 10x Genomics generate revenue?
According to its financial disclosures, 10x Genomics generates revenue from instruments, consumables, services, and license and royalty revenue. It further categorizes products into single cell (Chromium) and spatial (Visium and Xenium) offerings, and reports revenue by these categories. - What are 10x Genomics’ main product platforms?
The company’s public materials highlight the Chromium platform for single cell analysis and the Visium and Xenium platforms for spatial biology. It also references assays and workflows such as Chromium Flex, GEM-X 3' assays and Xenium Protein for spatial multiomic analysis. - In which research areas are 10x Genomics’ products used?
10x Genomics states that its products are used in research leading to breakthroughs in oncology, immunology, neuroscience and other areas. Company announcements describe applications in autoimmune disease research, solid tumor profiling, immuno-oncology and transplantation. - Who uses 10x Genomics’ technologies?
The company indicates that its customers include academic and translational researchers and biopharmaceutical companies. Its collaborations involve institutions such as academic medical centers, cancer institutes, research consortia and organizations focused on immuno-oncology and transplantation. - What is meant by single cell and spatial biology in the context of 10x Genomics?
In 10x Genomics’ descriptions, single cell biology refers to analyzing individual cells to understand their molecular characteristics, while spatial biology refers to studying cells within their spatial context in tissues. The company’s platforms are designed to generate data that capture these dimensions. - On which exchange does 10x Genomics trade and under what symbol?
10x Genomics’ Class A common stock is listed on The Nasdaq Stock Market LLC under the trading symbol TXG, as reported in its SEC filings. - How does 10x Genomics communicate important information to investors?
The company states that it uses SEC filings, its website, press releases, public conference calls, public webcasts and its social media accounts as means of disclosing information, including material non-public information, and for complying with its disclosure obligations under Regulation FD.